Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
Antibacterial Agent 255 is a selective inhibitor of 4-diphosphocytidyl-2-C-methyl-D-erythritol (IspE), demonstrating potent antibacterial activity with IC50 values of 13.0 µM for E. coli IspE, 8.0 µM for K. pneumoniae IspE, and 20 µM for A. baumannii IspE. This compound is instrumental in the study of bacterial biosynthesis pathways and can be utilized in antibacterial drug development research. -
Bacterial Inhibitor
Ethionamide hydrochloride is an antituberculosis agent that acts as a bacterial inhibitor. It disrupts mycobacterial cell wall synthesis by inhibiting fatty acid synthesis, leading to potential bacteriostatic or bactericidal effects based on concentration and microorganism susceptibility. Ethionamide hydrochloride forms an adduct with NAD+, which is crucial for its antimicrobial activity. This compound is primarily utilized in research for understanding tuberculosis treatment and the mechanisms of drug resistance in Mycobacterium tuberculosis. -
Antibacterial Agent
5-Hydroxymethyl flucloxacillin is an active metabolite of Flucloxacillin, targeting bacterial infections. This compound demonstrates notable antibacterial activity, making it useful for research applications focused on antimicrobial resistance and bacterial pathogenesis studies. Its efficacy in inhibiting bacterial growth supports investigations into therapeutic strategies for treating infections caused by resistant strains. -
Antibiotic
Andrimid is a lipoacyl peptide that functions as an antibiotic through its action on bacterial cell envelope synthesis. It demonstrates significant antimicrobial activity, making it a valuable compound for researching antibiotic mechanisms and resistance. Additionally, Andrimid has potential applications in both biomedical research and agricultural biotechnology, particularly in developing strategies for disease control. -
Anti-Bacterial Agent
Saquayamycin C is an anti-bacterial agent with significant antimicrobial activity, though it exhibits a weaker efficacy against Gram-negative bacteria. This compound also demonstrates cytotoxic effects against leukemia P388 cells, including those resistant to Adriamycin. Its applications extend to research in cancer biology and microbial resistance, making it valuable for studies focused on therapeutic development and resistance mechanisms. -
Bacterial Inhibitor
Allergen Gal d 4 (46-61), chicken is a peptide derived from hen egg white lysozyme, exhibiting bacterial inhibitory activity. This compound is utilized in research related to allergenic responses and microbial interactions, making it significant in studies of food allergies and immunological reactions. Its targeted application in bacterial inhibition aids in understanding the role of allergens in various biological systems. -
Antibacterial Agent
Maniladiol is a triterpenoid that serves as an antibacterial agent targeting Mycobacterium tuberculosis. It demonstrates significant antitubercular activity, exhibiting a minimum inhibitory concentration (MIC) of 4 mg/mL against the H37Rv strain of M. tuberculosis. This compound is valuable for research focused on tuberculosis infection mechanisms and potential therapeutic applications. -
Antibacterial Agent
8-Desmethyleleutherin is an antibacterial agent derived from the bulbs of Eleutherine americana. It exhibits potent antibacterial activity with minimal inhibitory concentration (MIC) values of 62.5 µg/mL against Staphylococcus aureus strains ATCC27664 and ATCC25923. This compound is valuable for research applications focusing on bacterial resistance and the development of new antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 80 is an antibacterial compound that targets bacterial cell wall synthesis. It exhibits significant inhibitory activity against a wide range of gram-positive and gram-negative bacteria. This reagent is valuable for research applications aimed at investigating bacterial resistance mechanisms and developing novel antimicrobial therapies. -
Antibacterial Agent
Xanthoascin is a natural phenolic metabolite that exhibits strong antibacterial activity. Derived from the fermentation products of the endophytic fungus Aspergillus sp. IFB-YXS found in Ginkgo biloba leaves, Xanthoascin demonstrates a minimum inhibitory concentration (MIC) of 0.3125 µg/mL against Clavibacter michiganense subsp. sepedonicus, along with moderate activity against other bacterial pathogens (MIC = 5-20 µg/mL). Its mechanism involves disrupting bacterial cell membrane permeability, resulting in the leakage of nucleic acids. This compound holds potential for research applications in antimicrobial development and the study of plant pathogen interactions. -
Antibacterial Agent
Penamecillin is an acetoxymethyl ester of Penicillin G designed as an orally active antibacterial agent. It acts by inhibiting bacterial cell wall synthesis, rendering it effective against a range of gram-positive bacteria. This compound is primarily utilized in research applications focused on understanding bacterial resistance and the pharmacodynamics of antibiotic treatments. -
Antibacterial Agent
Anti-MRSA agent 8 is a DAPG derivative that exhibits potent antibacterial activity. This compound targets bacterial cell membranes, disrupting their integrity and function. It is particularly valuable for research focused on methicillin-resistant Staphylococcus aureus (MRSA), making it an essential tool for studies on antibiotic resistance and bacterial infection. -
Antibacterial Agent
Antibacterial Agent 57 is an antibacterial compound that exhibits potent activity against a variety of bacterial strains. Its primary mechanism involves the inhibition of bacterial growth, making it a valuable tool for research applications focused on antimicrobial resistance and the development of new therapeutic agents. This compound is essential for studies investigating the efficacy of novel antibacterial therapies and understanding bacterial pathogenesis. -
Bacterial Inhibitor
Levonadifloxacin arginine is a potent bacterial inhibitor targeting both methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MSSA and MRSA). This broad-spectrum antistaphylococcal agent exhibits significant antimicrobial activity and has been shown to reduce the phagocytosis of MRSA and MSSA strains by monocytic THP-1 cells. Its applications in research include studies focused on bacterial resistance mechanisms and potential therapeutic interventions for staphylococcal infections. -
VIM-Type Metallo-β-lactamase Inhibitor
Metallo-β-lactamase-IN-7 is a specific inhibitor of VIM-type metallo-β-lactamases, demonstrating potent inhibition with IC50 values of 0.019 μM for VIM-2, 13.64 μM for VIM-1, and 0.38 μM for VIM-5. This compound enhances the antibacterial efficacy of Meropenem against Gram-negative bacterial strains, making it a valuable tool in combating antibiotic resistance in microbial research. Its application is crucial for studies focused on understanding and overcoming metallo-β-lactamase mediated resistance mechanisms. -
Antibacterial Agent
WU-FA-01 is a hydrogenated derivative of WU-FA-00, functioning primarily as an antibacterial agent. It demonstrates potent antibacterial activity against Gram-positive bacterial strains, making it a valuable compound for research into antimicrobial therapies. Additionally, WU-FA-01 exhibits some anti-inflammatory properties, suggesting potential applications in studies focused on the interplay between bacterial infections and inflammation. -
Antibacterial Agent
Isomagnolol is a lignan known for its antibacterial properties. Isolated from the roots of the tea plant, it exhibits significant antimicrobial activity, making it a valuable reagent for research focused on combating bacterial infections. This compound can be utilized in studies investigating the mechanisms of action behind antibacterial agents and in the development of novel therapeutic strategies. -
Bacterial Inhibitor
Antibacterial Agent 53 is a potent bacterial inhibitor that targets specific bacterial pathways to disrupt cell function. Demonstrating significant antibacterial activity, this compound is primarily utilized in research focusing on the development of novel antimicrobial agents and therapeutic strategies against bacterial infections. Its effectiveness makes it a valuable reagent for studies aimed at understanding bacterial resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 109 is an effective antibacterial compound that targets protein synthesis by inhibiting the elongation of peptide chains. It demonstrates strong activity against both gram-positive and gram-negative bacteria while exhibiting non-mutagenic properties. This compound is suitable for research applications focused on bacterial resistance and the mechanisms of antibiotic action. -
Bacterial Inhibitor
Anti Gram-Positive/Negative Bacteria Agent 1 is a bacterial inhibitor that functions through the mechanism of an antibiotic conjugate linked to an artificial MECAM-based siderophore. This compound exhibits significant antibacterial activity against both Gram-positive and Gram-negative bacteria. It is suitable for research applications aimed at studying bacterial infections and developing new antimicrobial strategies. -
Antibacterial Agent
Antibacterial Agent 117 is a triazole derivative that functions as an effective antibacterial agent targeting MetAP1 in Rickettsia prowazekii, exhibiting an IC50 value of 15 μM. This compound demonstrates the ability to inhibit rickettsial growth, making it valuable for research focused on infectious diseases. Its potential applications include investigating mechanisms of bacterial resistance and developing therapeutic strategies against rickettsial infections. -
Antibacterial Agent
ST166 free acid is an inhibitor of the PhoP-DNA complex formation, exhibiting IC50 values of 18 µM and 24 µM against PhoP and MtrAC binding to DNA, respectively. This compound demonstrates significant antibacterial activity against Macrobacterium marinum, making it a valuable tool for studying bacterial infections and pathways. Its application in research contributes to the understanding of bacterial resistance mechanisms and the development of novel antibacterial strategies. -
Bacterial Inhibitor
Antitubercular agent-9 is a bacterial inhibitor that demonstrates effective antitubercular activity, with a minimum inhibitory concentration (MIC) ranging from 1.03 to 2.32 μM. This compound is suitable for research focused on tuberculosis treatment mechanisms and the development of new antitubercular therapies. It serves as a valuable tool for understanding bacterial resistance and evaluating potential drug candidates in infectious disease research. -
Antibacterial Agent
Antibacterial Agent 143 (Compound 5a) is a synthetic antibacterial agent that demonstrates effective antimicrobial activity with minimum inhibitory concentrations (MICs) of 25 μg/mL against Bacillus subtilis ATCC 6633 and Staphylococcus aureus ATCC 6538, and 50 μg/mL against Pseudomonas aeruginosa ATCC 13525 and Escherichia coli ATCC 35218. Its potency against a range of Gram-positive and Gram-negative bacteria makes it a valuable tool in antibacterial research and the development of novel therapeutic strategies. This compound is suitable for studies focusing on bacterial resistance mechanisms and the evaluation of new antibacterial formulations. -
Bacterial Inhibitor
Antibacterial Agent 62 is a novel redox cycling compound that targets bacterial cells, demonstrating potent bactericidal activity against both growing and nutrient-starved phenotypically drug-resistant nongrowing bacteria. This reagent is particularly useful in research applications focused on tuberculosis and the development of new antibacterial therapies. Its unique mechanism of action may also aid in understanding resistance mechanisms in various bacterial strains. -
Antibacterial Agent
D-K6L9 is an antibacterial agent that exhibits significant antimicrobial and antibiofilm activities against Pseudomonas aeruginosa strains isolated from cystic fibrosis patients. This compound demonstrates stability and resistance to degradation by proteases found in cystic fibrosis sputum, which contributes to its effective performance. Importantly, D-K6L9 does not promote bacterial resistance, making it a valuable tool for research in infectious diseases associated with cystic fibrosis. -
Antibacterial Agent
c[Arg-Arg-Arg-Arg-Nal-Nal-Nal] is a cyclic peptide exhibiting potent antibacterial properties, effective against both drug-resistant Gram-positive and Gram-negative bacteria. It demonstrates minimum inhibitory concentrations (MICs) of 3.1 µg/mL against MRSA (ATCC BAA-1556) and S. aureus (ATCC 29213), and 12.5 µg/mL and 25 µg/mL against P. aeruginosa (ATCC 27883) and E. coli (ATCC 25922), respectively. This compound serves as a crucial tool for researchers exploring novel antibacterial strategies and understanding resistance mechanisms in pathogenic bacteria. -
Antibacterial Agent
Antibacterial Agent 46 is a potent antibacterial agent, specifically developed for targeting bacterial infections. It demonstrates significant inhibitory activity against a range of pathogenic bacteria, making it a valuable tool for research in the field of microbiology. This compound can be utilized in studies aimed at understanding bacterial resistance mechanisms and developing new antibacterial therapies. -
Bacterial Inhibitor
Antibacterial Agent 30 is a potent bacterial inhibitor, exhibiting significant in vitro activity against Xanthomonas oryzae pv. oryzae with an EC50 value of 1.9 μg/mL. This compound is suitable for research applications aimed at understanding bacterial pathogenesis and developing new antibacterial strategies. -
Bacterial Inhibitor
NDM-1 inhibitor-2 is a selective inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) that effectively inhibits NDM-1 enzymatic activity. This compound demonstrates significant antibacterial activity against drug-resistant bacterial strains that overexpress NDM-1, providing insights into overcoming resistance mechanisms. Additionally, NDM-1 inhibitor-2 can enhance the efficacy of the carbapenem antibiotic meropenem, resulting in a synergistic effect that supports research in antimicrobial therapy and resistance management. -
Antibacterial Drug
1,3,7-Trihydroxy-2-prenylxanthone is a xanthone derivative with antibacterial properties primarily targeting vancomycin-resistant enterococci (VRE). It demonstrates a minimum inhibitory concentration (MIC) of 6.25 mg/ml against strains including Enterococcus faecalis, Enterococcus faecium, and Enterococcus gallinarum. This compound is valuable for research applications focused on antibiotic resistance and the development of novel antibacterial agents. -
Antibacterial Drug
(±)-ε-Viniferin is a racemic mixture known for its antibacterial properties, primarily targeting Gram-positive bacteria. It demonstrates antimicrobial activity against Streptococcus pneumoniae, with a minimum inhibitory concentration (MIC) of 20 μM. Additionally, (±)-ε-Viniferin exhibits P450 inhibitory effects and protective properties for hepatocytes, making it a valuable compound in research on antibacterial agents and hepatoprotection. -
Bacterial Inhibitor
1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial agent targeting a range of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). Its significant antibacterial activity makes it a valuable candidate for addressing drug-resistant bacterial infections. Research applications may include investigations into its efficacy as a therapeutic tool against prevalent multidrug-resistant pathogens in clinical settings. -
Antibacterial Peptide
LDKA is a helical membrane-active antibacterial peptide that primarily disrupts bacterial membranes. This compound demonstrates significant antibacterial activity against both Gram-positive bacteria, such as Staphylococcus aureus, and Gram-negative bacteria, including Escherichia coli and Pseudomonas aeruginosa, in nutrient-rich environments. The minimum inhibitory concentrations (MICs) for LDKA range from 10 to 70 μM, making it a valuable tool for research in antibacterial therapeutic development. -
Antibacterial Drug
Galbinic acid (α-Acetylsalazinic acid) is an antibacterial compound that targets and inhibits the growth of various bacterial strains. It demonstrates significant activity against Gram-positive bacteria such as Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus, with minimum inhibitory concentrations (MICs) of 62.5 μg/ml and 250 μg/ml, respectively. Additionally, Galbinic acid exhibits antibacterial effects on the Gram-negative bacterium Escherichia coli, with an MIC of 125 μg/ml. This compound is valuable for research applications focused on developing new antibacterial agents. -
Antibacterial Agent
Corianin is a sesquiterpene lactone extracted from the fruits of Coriaria ruscifolia, exhibiting potent antibacterial properties. It demonstrates effectiveness against Staphylococcus aureus and Staphylococcus epidermidis, making it a valuable compound for research into antibacterial mechanisms and potential therapeutic applications. This compound may serve as a candidate in the development of new antimicrobial agents. -
Bacterial Inhibitor
Altertoxin III is a bacterial inhibitor known for its mutagenic effects on Salmonella typhimurium strains TA98, TA100, and TA1537. Derived from an extract of the A. alternata isolate, this compound exhibits significant mutagenicity as demonstrated in the Ames assay. It is valuable for studies focused on mutagenesis and the mechanisms of bacterial resistance. -
Antibacterial Agent
Antibacterial Agent 33 functions primarily as an antibacterial agent, exhibiting enhanced efficacy by significantly lowering the minimum inhibitory concentration (MIC) of Ceftazidime. This compound demonstrates potent antibacterial activity against a range of pathogenic bacteria, making it a valuable tool for research in antibiotic synergy and resistance mechanisms. Its applications include studies in microbiology and pharmacology, particularly in the development of novel antibacterial therapies. -
Bacterial Inhibitor
Heraclenol is a coumarin compound that targets bacterial pathogens. Isolated from the fruits of Angelica lucida, Heraclenol demonstrates notable antibacterial activity, making it valuable for research applications focused on combatting bacterial infections. Its mechanism of action contributes to the understanding of antimicrobial resistance and the development of new therapeutic strategies. -
Antibacterial Agent
Antibacterial Agent 74 is a potent anti-Salmonella compound that demonstrates significant antibacterial activity against Salmonella spp. This reagent is essential for research applications focused on understanding bacterial infections and developing novel therapeutic strategies to combat Salmonella-related diseases. -
Bacterial Inhibitor
L-689065 is a potent bacterial inhibitor that acts by targeting essential bacterial processes. It exhibits significant antimicrobial activity against a range of bacterial strains, making it a valuable reagent for studies on bacterial resistance and infection mechanisms. This compound is applicable in microbiological research focused on identifying new antibacterial agents and understanding the pathways of bacterial growth inhibition. -
Antibiotic Agent
Sulfadimethoxypyrimidine-d4 is a deuterium-labeled derivative of Sulfadimethoxypyrimidine, a sulfonamide antibiotic known for its broad-spectrum antibacterial activity. This compound acts by inhibiting bacterial dihydropteroate synthase, a key enzyme in folate biosynthesis, thereby disrupting DNA synthesis and bacterial growth. It is valuable for pharmacokinetic studies and metabolic research concerning sulfonamide antibiotics. -
Bacterial Inhibitor
FK-518 is a potent inhibitor of AmpC β-lactamase, targeting resistance mechanisms in bacteria. This compound exhibits strong antimicrobial activity against Pseudomonas aeruginosa strains that overexpress AmpC β-lactamase, making it a valuable tool in the study of bacterial infections. FK-518 is particularly useful for research investigating therapeutic strategies against resistant bacterial strains. -
Antibacterial Agent
Antibacterial Agent 197 (compound 1-deAA) functions as a termination inhibitor of non-classical anhydroglycosyl receptors and anhydrowall peptide-type peptidoglycan in bacterial TGase. This compound exhibits notable antibacterial activity against Staphylococcus aureus and can enhance the efficacy of Vancomycin, serving as an effective antibacterial adjuvant. It is suitable for research applications focused on antibiotic resistance and the development of novel antibacterial strategies. -
Antibacterial Agent
Isobavachromene is an antibacterial agent that exhibits potent activity against various bacterial strains. Its primary mechanism involves the disruption of bacterial cell wall synthesis, leading to cell lysis and death. This compound is valuable for research applications focused on exploring novel antibacterial therapies and understanding microbial resistance mechanisms. -
Antibacterial Agent
MAC173979 is an inhibitor of para-aminobenzoic acid (PABA) synthesis in Escherichia coli. This compound exhibits significant antibacterial activity, making it a valuable tool for the exploration of antibacterial drug development and mechanisms of resistance. Researchers can utilize MAC173979 to study the efficacy of novel antibacterial agents and develop therapeutic strategies targeting bacterial infections. -
Antibacterial Agent
Antibacterial Agent 43 is a potent antibacterial compound targeting bacterial strains implicated in various infections. This agent exhibits significant antimicrobial activity, making it suitable for investigating the mechanisms of bacterial resistance and the development of new therapeutic strategies. Its applications extend to research focused on treating bacterial infections and understanding the pharmacodynamics of antibacterial therapies. -
Antibacterial agent
PuroA is an antibacterial agent derived from the tryptophan-rich domain of Puroindoline a. It exerts its antibacterial activity by interacting with bacterial membranes, disrupting their integrity. This compound is valuable for research applications focused on understanding bacterial resistance and developing novel antimicrobial strategies. -
Antibacterial Agent
Tetrahydrobostrycin is a secondary metabolite derived from Aspergillus species, functioning primarily as an antibacterial agent. It demonstrates mild inhibitory activity against pathogens such as Staphylococcus aureus and Escherichia coli, with observed inhibition zones measuring 15 mm and 9.2 mm in diameter, respectively, at a concentration of 100 mg/disc. This compound may be useful in microbiological research and investigations into antibacterial mechanisms. -
Bacterial Inhibitor
RO7075573 is a bacterial inhibitor that targets the lipopolysaccharide (LPS) transport machinery in Acinetobacter species. This compound has demonstrated protective effects in preclinical models against Acinetobacter baumannii infections, highlighting its potential for therapeutic applications in combating antibiotic-resistant bacterial pathogens. Research applications may include studying bacterial pathogenesis and developing new antibiotic strategies.
