PF-4136309

Catalog No.: A15127
CCR2 antagonist
PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.
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Product Name Price Stock Qty
PF-4136309 5mg
$72.00
In stock
PF-4136309 10mg
$124.00
In stock
PF-4136309 50mg
$368.00
In stock
PF-4136309 100mg
$736.00
In stock
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Biological Activity
Discription PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.
Targets
Target Value
Product Information
Catalog Num A15127
Formula C29H31F3N6O3
Molecular Weight 568.59
CAS Number 1341224-83-6
SMILES O[C@]1(CC[C@](CC1)([H])N[C@@H]2CN(CC2)C(CNC(C3=CC=CC(C(F)(F)F)=C3)=O)=O)C4=NC=C(C=C4)C5=NC=CC=N5
Synonyms INCB8761
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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