PF-4136309

Catalog No.: A15127

CCR2 antagonist

PF-4136309

PF-4136309 Chemical Structure

CAS NO. 1341224-83-6

PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.

Availability: In stock

Package Price Qty
5 mg
$72.00
10 mg
$124.00
50 mg
$368.00
100 mg
$736.00
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Biological Activity

PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.59 mL 87.94 mL 175.87 mL
0.5 mM 3.52 mL 17.59 mL 35.17 mL
1 mM 1.76 mL 8.79 mL 17.59 mL
5 mM 0.35 mL 1.76 mL 3.52 mL

*The above data is based on the productmolecular weight 568.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15127
Actions Antagonist
M. Wt 568.59
Formula C29H31F3N6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1341224-83-6
Synonyms INCB8761
SMILES O[[email protected]]1(CC[[email protected]](CC1)([H])N[[email protected]@H]2CN(CC2)C(CNC(C3=CC=CC(C(F)(F)F)=C3)=O)=O)C4=NC=C(C=C4)C5=NC=CC=N5

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