Afabicin

Catalog No.: A19501
Afabicin (Debio 1450) is the prodrug of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
Grouped product items
Product Name Price Stock Qty
Afabicin 1mg
$320.00
In stock
Afabicin 5mg
$960.00
In stock
Afabicin 10mg
$1,600.00
In stock
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Biological Activity
Discription Afabicin (Debio 1450) is the prodrug of Debio1452, specifically targeting staphylococci without significant activity against other Gram-positive or Gram-negative species. Debio1452 is an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci.
Product Information
Catalog Num A19501
Formula C23H24N3O7P
Molecular Weight 485.43
CAS Number 1518800-35-5
SMILES O=P(O)(O)OCN1C2=NC=C(/C=C/C(N(C)CC(OC3=CC=CC=C43)=C4C)=O)C=C2CCC1=O
Synonyms Debio 1450, Debio1450, Debio-1450; AFN-1720, AFN1720, AFN 1720
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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