Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Drug
Thalrugosaminine is a benzylisoquinoline alkaloid that exhibits antibacterial activity through its action on bacterial cell walls. It demonstrates effective antibacterial properties, with minimum inhibitory concentration (MIC) values ranging from 64 to 128 µg/ml. This compound is valuable in research focused on antibiotic development and understanding antibacterial mechanisms. -
Antibacterial Agent
Ianthelliformisamine B diTFA is a bromotyrosine-derived antibacterial agent that targets bacterial strains. It exhibits potent activity against Escherichia coli and Staphylococcus aureus, with minimum inhibitory concentrations (MICs) of 14.5 μM and 144.7 μM, respectively. This compound is valuable for research applications focused on antibacterial mechanisms and the development of new antimicrobial therapies. -
Antibacterial Agent
Lithooxazoline is a potent antibacterial agent that targets a range of bacterial strains. This compound exhibits significant antimicrobial activity, making it valuable for research in infectious diseases and antibiotic resistance. Its effectiveness in inhibiting bacterial growth positions it as a useful tool for investigating new antibacterial therapies. -
Antibacterial Agent
Olanexidine gluconate is an antibacterial agent with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. As an effective antiseptic, it demonstrates utility in the research of infection and inflammatory processes. Its diverse antimicrobial properties make it a valuable tool for studies focused on infection control and related therapeutic applications. -
Antimycobacterial Agents
B 746 is a clofazimine analog that targets Mycobacterium avium complex (MAC), exhibiting significant antimycobacterial activity. This compound is particularly noteworthy for its effectiveness in studies examining alternative treatment regimens for MAC infections. Its unique properties make it a valuable reagent in research focused on combating mycobacterial diseases. -
Antibiofilm Agent
1,3-β-Glucanase targets the β-1,3-glucan component of the biofilm matrix in Candida albicans. By degrading this polysaccharide, it effectively disrupts the biofilm structure, thereby enhancing the efficacy of antimicrobial treatments. This enzyme is utilized as an antibiofilm agent in various research applications focused on fungal infections and biofilm-related challenges. -
Anti-bacterial agent
S 3578 sulfate is a broad-spectrum antibacterial agent targeting various bacterial pathogens, including methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. With minimum inhibitory concentrations (MIC) of 0.78-3.13 μg/mL for MRSA and 1.56-6.25 μg/mL for Pseudomonas aeruginosa, S 3578 sulfate demonstrates potent antimicrobial activity. This compound is utilized in research related to infectious diseases, particularly in the study of antibiotic resistance and bacterial infections. -
Bacterial Inhibitor
NBTIs-IN-4 is a potent bacterial inhibitor targeting DNA gyrase and topoisomerase IV in Gram-positive pathogens. It exhibits significant antibacterial activity while maintaining a low frequency of resistance. This compound is valuable for research applications aimed at understanding bacterial resistance mechanisms and developing new antibacterial therapies. -
Antibacterial Agent
Antibacterial Agent 141 (Compound B14) targets bacterial cell membranes and exhibits noteworthy antibacterial activity against four plant pathogens: Xanthomonas oryzae pv. oryzae (Xoo), Xanthomonas campestris pv. campestris (Xac), Pseudomonas syringae pv. actinidiae (Psa), and Clavibacter michiganensis subsp. michiganensis (Cmm), with an EC50 value of 1.28 μM. This compound effectively inhibits cell membrane formation and alters cell permeability, making it a valuable tool for research on plant pathogen control and resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 142 is an aromatic hydrazide that exhibits significant antibacterial activity. This compound functions as a bacteriostatic agent and is capable of inhibiting biofilm formation, making it valuable in studies focused on bacterial growth and infection control. Its properties support research into novel antibacterial therapies and the development of interventions against biofilm-associated infections. -
Bacterial Inhibitor
BPH-1358 free base is a potent inhibitor of human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS), exhibiting IC50 values of 1.8 μM and 110 nM, respectively. This compound demonstrates significant antibacterial activity against Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of approximately 250 ng/mL. BPH-1358 free base is suitable for research applications aimed at understanding bacterial resistance mechanisms and developing novel antibacterial strategies. -
Bacterial Inhibitor
Lankacidin C 8-acetate is an antibiotic that targets bacterial pathogens through its antibacterial activity. This compound, part of the Lankacidin antibiotic group, exhibits significant inhibitory effects against specific bacterial strains. Additionally, Lankacidin C 8-acetate can react with various acyl donors to generate ester derivatives, highlighting its relevance in antibiotic synthesis and development for research applications. -
Antimicrobial Agent
Lapyrium chloride is a broad-spectrum antimicrobial agent that targets a variety of microorganisms. It exhibits potent antiseptic and disinfectant properties, making it suitable for use in both clinical and laboratory settings. This reagent is ideal for applications involving the control of bacterial and fungal contamination. -
Bacterial Inhibitor
Macranthoside A is a triterpene glycoside that acts as a bacterial inhibitor. It demonstrates significant antimicrobial activity, making it a useful compound for research applications aimed at studying bacterial infections and evaluating potential therapeutic agents against microbial resistance. -
Bacterial Inhibitor
I-A09 is a bacterial inhibitor that demonstrates significant antitubercular activity against Mycobacterium tuberculosis H37Rv. This compound and its derivatives, particularly the 1,2,3-triazole-adamantylacetamide hybrids synthesized via copper-catalyzed click chemistry, display enhanced efficacy with a minimum inhibitory concentration (MIC) as low as 3.12 μg/mL. These novel analogues, particularly N-(1-adamantan-1-yl)-2-(4-(phenanthren-2-yl)-1H-1,2,3-triazol-1-yl)acetamide (5t), have applications in research focused on tuberculosis treatment and the development of new antitubercular agents. -
Antibacterial Agent
Antibacterial Agent 76 functions by inhibiting bacterial cell wall synthesis, thereby exerting its antibacterial activity. This compound demonstrates effectiveness against a variety of Gram-positive and Gram-negative bacteria, making it suitable for research in antimicrobial resistance and the development of new antibacterial therapies. Antibacterial Agent 76 is ideal for studies focused on bacterial infections and the mechanisms of action of antibacterial compounds. -
Anti-Bacterial Agent
Paulomycin A is an anti-bacterial agent that demonstrates potent activity against Gram-positive bacteria. It effectively inhibits the growth of Staphylococcus aureus, including strains resistant to penicillin, streptomycin, neomycin, and macrolide antibiotics. This compound is valuable for research applications focused on antibiotic resistance and the development of new therapeutic strategies against bacterial infections. -
Bacterial Inhibitor
Antibacterial Agent 95 is a potent bacterial inhibitor with a primary target of Mycobacterium tuberculosis. Demonstrating a minimum inhibitory concentration (MIC) as low as 0.3 μM against the reference strain H37Rv, this 2-(quinoline-4-methoxy)acetamide compound effectively inhibits the growth of Mycobacterium tuberculosis in macrophage models of tuberculosis infection. Its exceptional activity makes it a valuable tool for research in antitubercular drug development. -
β-lactamase Inhibitor
Brobactam is a potent synthetic β-lactamase inhibitor designed to combat antibiotic resistance by inhibiting β-lactamase enzymes. It exhibits broad-spectrum antibacterial activity, making it valuable in the study and treatment of β-lactamase-mediated resistance in various bacterial infections. Research applications include the evaluation of combination therapies and the development of novel antibacterial agents. -
Antibacterial Agent
Obtusalin is a triterpenoid compound with identified antibacterial properties. Isolated from Rhaponticum dauricum, it exhibits UV absorption at 210 nm. This compound serves as a valuable tool in microbiological research to study bacterial inhibition and could potentially contribute to the development of new antibacterial agents. -
Antibacterial Agent
22-((4-Methoxyphenyl)urea-1-yl)-22-deoxypleuromutilin is an antibacterial agent that targets Gram-positive pathogens (GPPs) and Mycoplasma pneumoniae. This pleuromutilin derivative exhibits potent antibacterial activity, making it suitable for research focused on combating infections caused by resistant bacterial strains. Its unique mechanism of action allows for exploration in various applications within antibiotic development and microbiological studies. -
Dihydroisocoumarin Derivative
Aspergillumarin B is a dihydroisocoumarin derivative isolated from the endophytic fungus Aspergillus sp. It exhibits weak antibacterial activity against Staphylococcus aureus and Bacillus subtilis. This compound is of interest in biological research for its potential applications in studying antibacterial mechanisms and fungal metabolites. -
Antibacterial agent
1-Methyl-2-(8E)-8-tridecenyl-4(1H)-quinolinone functions as a potent antibacterial agent targeting Helicobacter pylori. It demonstrates notable antibacterial activity, with an MIC50 value of 22 µM and an MIC90 value of 50 µM against H. pylori Strain 51. This compound is valuable for research focused on the treatment of gastric and duodenal ulcers. -
Bacterial Inhibitor
Pelagiomicin A is a phenazine antibiotic with a primary mechanism targeting bacterial cell functions. This compound demonstrates significant antibacterial activity against both Gram-positive and Gram-negative bacteria, making it a valuable tool for research in microbial resistance. Additionally, Pelagiomicin A has shown promising antitumor effects in vitro and in vivo, underscoring its potential applications in cancer research. Its structure has been elucidated through a combination of spectroscopic data and synthesis techniques, contributing to the understanding of its biological properties. -
Antibacterial Agent
Antibacterial Agent 42 is a potent antibacterial compound that enhances the efficacy of Ceftazidime by significantly lowering its minimum inhibitory concentration (MIC). This agent exhibits strong activity against a range of bacterial pathogens, making it valuable in the development of combination therapies. Its applications extend to research focusing on antibiotic resistance and the optimization of existing antibacterial treatments. -
DHPS Inhibitor
Dihydropteroate synthase-IN-1 is a potent inhibitor of dihydropteroate synthase (DHPS), primarily targeting the folate biosynthesis pathway. This compound exhibits significant antimicrobial and antifungal properties, making it valuable for research in microbial resistance and pathogenicity studies. Additionally, Dihydropteroate synthase-IN-1 has implications in diagnostics as a potential radio imaging agent, advancing the exploration of therapeutic interventions. -
Anti-bacterial Agent
Macatrichocarpin A is a flavanone exhibiting notable anti-bacterial activity. It demonstrates inhibitory effects against Bacillus subtilis, with a minimum inhibitory concentration (MIC) of 26.5 μM. This compound can be isolated from the leaves of Macaranga trichocarpa, making it a valuable candidate for research into antimicrobial agents. -
Non-beta-lactam Antibiotic
Lactivicin is a non-beta-lactam antibiotic that exhibits beta-lactam-like activity by binding to penicillin-binding proteins (PBPs). It demonstrates moderate efficacy against a broad spectrum of Gram-negative bacteria and high effectiveness against Gram-positive bacteria. This compound is valuable for research in antibiotic resistance and the mechanisms of bacterial cell wall synthesis. -
Antibacterial Agent
Decarboxy ciprofloxacin is an antibacterial agent primarily targeting bacterial pathogens. It exhibits significant antibacterial activity against various strains, including Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Bacillus subtilis, Enterobacter cloacae, Serratia marcescens, and shows particularly strong efficacy against Escherichia coli. This compound is valuable for research in the development of new antibacterial therapies and understanding antibiotic resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 78 is a potent antibacterial compound that targets bacterial cell wall synthesis. It exhibits significant activity against a variety of gram-positive and gram-negative bacteria, making it a valuable tool for investigating bacterial resistance mechanisms. This compound is suitable for research applications related to antibiotic development and microbiological studies. -
Antibacterial Agent
Antibacterial Agent 131 is a quinoline derivative that targets bacterial cell integrity. It exerts antimicrobial activity by inhibiting ergosterol production, leading to disruption of fungal cell membranes. This compound is suitable for research applications focused on evaluating antibacterial and antifungal activities, contributing to the development of new antimicrobial therapies. -
Antibacterial Agent
Antibacterial Agent 262 is a potent inhibitor of Xanthomonas oryzae pv oryzae, targeting bacterial growth and biofilm formation. This compound disrupts the integrity of bacterial cell membranes, leading to impaired viability and enhanced susceptibility to treatment. It is valuable for research applications focusing on bacterial pathogenicity, biofilm dynamics, and the development of novel antibacterial strategies. -
Antimycobacterial Agent
Antimycobacterial Agent-3 is an effective antimycobacterial compound targeting Mycobacterium tuberculosis (MTB), demonstrating activity against both sensitive strain H37Rv and drug-resistant clinical isolates, with a minimum inhibitory concentration (MIC) ranging from < 0.029 to 0.110 μM. This agent exhibits low cytotoxicity in cell-based assays, making it a valuable tool for research into tuberculosis treatment and resistance mechanisms. -
Antibacterial Agent
Antibacterial agent 278 (compound B1) is a potent antibacterial compound targeting Gram-positive bacteria. It demonstrates significant bactericidal activity, making it a valuable tool for research in the development of new antibacterial therapies. This agent is useful in studying mechanisms of bacterial resistance and evaluating antimicrobial efficacy. -
Antibacterial Agent
Furaltadone L-tartrate is a nitrofuran antibacterial agent primarily used in the study of infections, particularly in chickens infected with Salmonella enteritidis. This compound exhibits both inhibitory and bactericidal effects against Staphylococci in vitro. Its applications extend to various research contexts involving bacterial infections and treatment efficacy assessment. -
β-Lactamase Inhibitor
KSP-1007 is a bicyclic boronate compound functioning as a broad-spectrum β-lactamase inhibitor. It effectively targets class A, B, C, and D β-lactamases, including serine-type and metallo-type enzymes such as NDM, VIM, and IMP, in addition to Acinetobacter baumannii OXA-type enzymes. KSP-1007 enhances the antibacterial activity of Meropenem, decreasing its minimum inhibitory concentration (MIC) against carbapenemase-producing Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa. This reagent is suitable for research on bacterial infections and antibiotic resistance mechanisms. -
Antibacterial Agent
NLCQ-1 (NSC 709257) is an orally active antibacterial agent that specifically targets dormant Mycobacterium tuberculosis. This compound exhibits significant potential for research into tuberculosis treatment, particularly in addressing latent infections. Its ability to act on dormant bacteria makes it a valuable tool in the study of mycobacterial resistance and the development of novel therapeutic strategies. -
Antibacterial Agent
LY 215890 is an orally active antibacterial agent targeting Escherichia coli EC14 and Klebsiella pneumoniae X26. This compound demonstrates effective antibacterial activity, making it suitable for research applications aimed at studying bacterial infections and resistance mechanisms. Its efficacy in selective bacterial inhibition supports investigations into novel therapeutic strategies in infectious disease management. -
Bacterial Inhibitor
2'-Hydroxy-2-methoxychalcone acts as a bacterial inhibitor, demonstrating significant antimicrobial activity against various bacterial strains. This synthetic chalcone derivative is valuable for research in understanding bacterial resistance mechanisms and developing new antimicrobial agents. Its structural properties facilitate the exploration of structure-activity relationships in the field of medicinal chemistry. -
Antibacterial Agent
Cefcanel is an orally active cephalosporin antibiotic targeting bacterial cell wall synthesis. It exhibits effective antibacterial activity against methicillin-susceptible strains of Staphylococcus aureus and Staphylococcus epidermidis, as well as Haemophilus influenzae and Moraxella catarrhalis. Cefcanel serves as a substrate for hydrolysis by various beta-lactamases, including TEM-1, TEM-3, and Moraxella Bro-1, making it a valuable tool for research on antibiotic resistance mechanisms and bacterial susceptibility testing. -
Antibacterial Agent
Antibacterial Agent 123 is a potent membrane-disrupting compound that targets antibiotic-resistant Gram-positive bacteria. This reagent demonstrates significant antibacterial activity, making it a valuable tool for research focused on developing novel therapeutic strategies against multi-drug resistant infections. Its ability to disrupt bacterial membranes positions it as an important candidate for studies aimed at understanding bacterial resistance mechanisms and evaluating new antibacterial therapies. -
Antibiotic
Griseolic acid C, an antibiotic compound, is identified as a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase (EC 3.1.4.17) with an IC50 of 0.12 μM, as demonstrated in studies utilizing rat brain extracts. Isolated from Streptomyces griseoaurantiacus SANK43894, Griseolic acid C exhibits significant biological activity that may be beneficial in various research applications related to cellular signaling and microbial resistance. -
Bacterial Inhibitor
Chinfloxacin is a bacterial inhibitor that exerts antibacterial activity against a range of clinical isolates in vitro. Demonstrating a concentration-dependent bactericidal effect, Chinfloxacin shares antibacterial efficacy comparable to that of moxifloxacin. This compound is suitable for research applications focused on bacterial pathogenicity and the development of new antimicrobial agents. -
Bacterial Inhibitor
Phenethicillin potassium is a β-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting penicillin-binding proteins. It demonstrates significant antibacterial activity against a range of Gram-positive bacteria, making it valuable in research applications focused on antimicrobial resistance and the mechanistic understanding of bacterial susceptibility. Its characteristic action profile facilitates studies in microbiology and pharmacology, providing insights into antibiotic efficacy and resistance mechanisms. -
Antibacterial Agent
Antibacterial Agent 58 functions as an antibacterial agent, exhibiting a significant reduction in the minimum inhibitory concentration (MIC) of Ceftazidime. This compound enhances the efficacy of existing antibiotics, making it a valuable tool for researchers studying antibiotic resistance and developing combination therapies. Its biological activity is pivotal for investigations into bacterial infections and the optimization of antibacterial strategies. -
Bacterial Inhibitor
Hikizimycin is a potent antibacterial agent that targets bacterial cell growth and division. This natural product exhibits significant antibacterial activity, making it a valuable tool for research focused on bacterial infections and their treatment. Its unique mechanism of action offers insights into new therapeutic strategies for combating antibiotic resistance. -
Bacterial Inhibitor
Antibacterial Agent 28 is a bacterial inhibitor with a mechanism targeting the growth and proliferation of pathogens such as Methicillin-resistant Staphylococcus aureus (MRSA). It exhibits antimicrobial activity with minimum inhibitory concentrations (MICs) ranging from 0.5 to 2 μg/mL. This reagent holds promise for research applications aimed at developing new treatments against resistant bacterial infections. -
Antibacterial Agent
Antibacterial Agent 55 is a potent antibacterial compound with demonstrated efficacy against a wide range of bacterial strains. This agent operates by disrupting vital cellular processes, leading to the inhibition of bacterial growth and replication. It is suitable for various research applications, including the study of bacterial resistance mechanisms and the development of novel antimicrobial therapies. -
MabA (FabG1) Inhibitor
FabG1-IN-1 is a selective inhibitor of MabA (FabG1), exhibiting an IC50 of 38 µM. This compound effectively impedes the enzymatic activity of FabG1, playing a crucial role in fatty acid biosynthesis. FabG1-IN-1 is applicable in research focusing on metabolic pathways and the development of antifungal therapies targeting lipid synthesis. -
Antibacterial Agent
ABT-255 hydrochloride is an orally active antibacterial agent targeting Mycobacterium tuberculosis. It demonstrates potent in vitro activity with a minimum inhibitory concentration (MIC) ranging from 0.016 to 0.031 μg/mL against both drug-susceptible and resistant strains, including those resistant to Rifampin and Ethambutol. Additionally, ABT-255 hydrochloride exhibits efficacy against Gram-positive and Gram-negative bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coli, effectively reducing viable counts of drug-resistant Mycobacterium tuberculosis in CF-1 mice. This compound is valuable for research applications focused on pulmonary tuberculosis.
