Narasin is a cationic ionophore antibiotic that effectively targets various microbial pathogens and acts as a coccidiostat agent. Its biological activity includes the inhibition of NF-κB signaling, leading to the induction of apoptosis in tumor cells. Narasin also exhibits antimicrobial, antiviral, and anticancer properties, specifically inhibiting tumor metastasis and the growth of ERα-positive breast cancer cells by inactivating the TGF-β/SMAD3 and IL-6/STAT3 signaling pathways, making it a valuable tool for cancer research and therapeutic applications.
Narasin is a cationic ionophore antibiotic that effectively targets various microbial pathogens and acts as a coccidiostat agent. Its biological activity includes the inhibition of NF-κB signaling, leading to the induction of apoptosis in tumor cells. Narasin also exhibits antimicrobial, antiviral, and anticancer properties, specifically inhibiting tumor metastasis and the growth of ERα-positive breast cancer cells by inactivating the TGF-β/SMAD3 and IL-6/STAT3 signaling pathways, making it a valuable tool for cancer research and therapeutic applications.
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