Microbiology

Items 6201-6250 of 6342

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  1. Antibacterial Agent, Antiviral Agent, Mutagenic Agent, Antiparasitic Agent

    Diiodohydroxyquinoline is an antibacterial, antiviral, mutagenic, and antiparasitic agent targeting various pathogens. It demonstrates significant anti-SARS-CoV-2 activity, with an EC50 value of 1.38 μM in VeroE6 cells, and shows effective antiparasitic properties. This compound is of particular interest for research applications involving inflammation, intestinal amebiasis, amebic liver abscess, and chronic nonspecific diarrhea. Additionally, Diiodohydroxyquinoline's mutagenic effects in animal models warrant further investigation in toxicological studies.
  2. Antibiotic

    Dirithromycin is a semi-synthetic macrolide antibiotic that functions by inhibiting bacterial protein synthesis. This compound exhibits potent activity against gram-positive bacteria, as well as various pathogens including Legionella spp., Helicobacter pylori, and Chlamydia trachomatis. Dirithromycin is primarily used in research applications related to antibiotic resistance and the mechanisms of microbial infections.
  3. Bacterial Inhibitor

    Enrofloxacin is a potent bacterial inhibitor belonging to the fluoroquinolone class. It exhibits an MIC90 value of 0.312 μg/mL against Mycoplasma bovis, demonstrating its effectiveness in combating bacterial infections. This compound is widely utilized in research applications focused on antibiotic resistance, microbiology, and the study of bacterial pathogens.
  4. Bacterial Inhibitor

    Florfenicol is a broad-spectrum antibacterial agent that exerts its effects primarily through inhibition of bacterial protein synthesis. This orally active compound demonstrates additional properties, including anti-inflammatory, pro-apoptotic, and immunomodulatory functions. Florfenicol is commonly utilized in research focused on bacterial infections and the modulation of immune responses.
  5. Bacterial Inhibitor

    Furaltadone hydrochloride is an orally active antibacterial agent targeting bacterial infections. It exhibits in vitro inhibitory effects on Staphylococcus and can be utilized in the study of intestinal Salmonella infections. Additionally, Furaltadone demonstrates potential inhibitory effects on allergic reactions, making it a valuable tool for research in microbiology and immunology.
  6. Fungicide

    8-Hydroxyquinoline is a lipophilic metal chelator primarily utilized as a fungicide. It demonstrates antimicrobial activity with a minimum inhibitory concentration (MIC) range of 27.56-55.11 μM against clinical isolates of Neisseria gonorrhoeae. The compound is capable of binding copper, facilitating its transport into cells, and has been observed to induce an increase in micronucleated polychromatic erythrocytes, with additional effects on hair depigmentation in murine models. This reagent is valuable for research in metal ion interactions and fungal pathology.
  7. Antibiotic

    Isepamicin sulfate is a broad-spectrum aminoglycoside antibiotic that targets bacterial protein synthesis. It demonstrates significant antimicrobial activity against Gram-negative non-fermenting bacteria, particularly those exhibiting high resistance to other antibiotics. In addition to its primary role as an antibiotic, Isepamicin sulfate has been shown to inhibit writhing responses induced by acetic acid, regulate vascular blood flow and pressure, and reduce spontaneous uterine contractions. Its diverse biological activities make Isepamicin sulfate a valuable reagent in studies of seizure mechanisms and other related physiological processes.
  8. β-lactam Antibiotic

    Mezlocillin sodium is a β-lactam antibiotic with a semisynthetic structure and extended-spectrum activity. It exhibits efficacy against a broad range of both gram-negative and gram-positive bacteria. Mezlocillin sodium is employed in research related to bacterial infections, making it a valuable tool for studying bacterial resistance and antibiotic efficacy.
  9. Antibiotic

    Nafcillin sodium monohydrate is an antibiotic that acts as a reversible inhibitor of β-lactamase. It is primarily utilized in the study of staphylococcal infections, demonstrating effective activity against penicillin-resistant strains. This compound is valuable for researchers investigating antibiotic resistance mechanisms and therapeutic options for bacterial infections.
  10. Antibiotic

    Netilmicin sulfate is a semisynthetic aminoglycoside antibiotic that targets bacterial ribosomes to inhibit protein synthesis. It demonstrates broad-spectrum antibacterial activity against various gram-negative bacteria, including aminoglycoside-susceptible and resistant strains such as Escherichia coli, Pseudomonas aeruginosa, and Enterobacter, as well as gram-positive strains like Staphylococcus aureus. With minimum inhibitory concentrations (MIC) ranging from 0.125 to 8 μg/mL, netilmicin sulfate is utilized in research related to antibiotic resistance and antimicrobial susceptibility testing.
  11. Veterinary Antibiotic

    Nithiamide is a veterinary antibiotic that functions by inhibiting bacterial growth. It is effective against a range of pathogenic microorganisms, making it valuable for treating infections in livestock and companion animals. Its unique mechanism of action positions it as an important tool in veterinary medicine, aiding in the management of bacterial diseases.
  12. Antibiotic

    Orbifloxacin is a fluoroquinolone antibiotic that targets bacterial DNA replication and proliferation. It exhibits bactericidal activity by inhibiting the growth of various bacterial strains, including canine-derived E. coli and Pseudomonas aeruginosa isolates. This compound is utilized in research applications focused on bacterial infections and the development of antimicrobial therapies.
  13. Antibiotic Agent

    Oxytetracycline dihydrate is a broad-spectrum antibiotic that functions primarily as a protein synthesis inhibitor. It effectively targets both Gram-negative and Gram-positive bacteria by preventing the binding of aminoacyl-tRNA to the ribosomal mRNA complex. Additionally, Oxytetracycline dihydrate exhibits anti-HSV-1 activity, making it relevant for research applications in microbiology and virology.
  14. Antibiotic

    Paromomycin sulfate is a broad-spectrum aminoglycoside antibiotic that acts primarily by binding to the RNA oligonucleotide at the A site of bacterial 30S ribosomes, leading to premature termination of mRNA translation and inhibition of protein synthesis. It exhibits both amebicidal and bactericidal properties, making it relevant in the study of bacterial and parasitic infections. Paromomycin sulfate serves as a valuable tool for researchers investigating antimicrobial resistance and the mechanisms of action of antibiotics.
  15. Bacterial Inhibitor

    Penicillin G sodium salt is a β-lactam antibiotic that inhibits bacterial cell wall synthesis by targeting penicillin-binding proteins. It demonstrates broad-spectrum antibacterial activity against various Gram-positive and some Gram-negative organisms. This reagent is commonly used in microbiological studies to evaluate susceptibility patterns and in the development of antibiotic resistance models.
  16. Bacterial Inhibitor

    Piperacillin sodium is a semisynthetic β-lactam antibiotic that targets penicillin-binding proteins, exhibiting potent bactericidal activity against a broad range of Gram-negative bacteria and select Gram-positive strains. This compound is widely utilized in pharmaceutical research to study bacterial infections and antibiotic resistance. Piperacillin sodium is frequently employed in combination with the β-lactamase inhibitor Tazobactam to enhance its efficacy against resistant bacterial strains.
  17. Bacterial Inhibitor

    Ribostamycin sulfate is a broad-spectrum bacterial inhibitor that targets protein synthesis by binding to the 30S and 50S ribosomal subunits. Additionally, it inhibits the chaperone activity of protein disulfide isomerase (PDI). This reagent is primarily utilized in pharmacokinetic studies and investigations of nephrotoxicity, making it valuable in the evaluation of antimicrobial efficacy and safety profiles.
  18. Antiprotozoal/Antibacterial Agent

    Ronidazole is a potent antiprotozoal and antibacterial agent that targets various protozoan infections. It is particularly effective against Tritrichomonas foetus in cat models, making it a valuable tool for veterinary research. Additionally, Ronidazole is utilized in the study of histomoniasis and swine dysentery, contributing to advancements in understanding these diseases in livestock and companion animals.
  19. HIV Inhibitor

    Salicylanilide is a known HIV inhibitor that targets HIV-1 integrase and reverse transcriptase. This compound exhibits significant antiviral potency, making it an important tool in the study of HIV biology and potential therapeutic strategies. Its multifaceted biological activities render it suitable for various research applications in the field of virology and antiviral drug development.
  20. Bacterial Inhibitor

    Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic that targets bacterial protein synthesis. It exhibits strong antibacterial activity, particularly against Gram-positive bacteria, making it an effective choice in studies of bacterial inhibition. This compound is useful for research applications involving the characterization of bacterial resistance and the development of new antimicrobial strategies.
  21. Antibiotic

    Sitafloxacin hydrate is a fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA replication. It exhibits broad-spectrum in vitro activity against various Gram-positive and Gram-negative bacteria, including anaerobic and atypical pathogens. Sitafloxacin hydrate is primarily utilized in research focusing on respiratory and urinary tract infections, making it a valuable tool for studying antibiotic resistance and bacterial pathogenesis.
  22. Bacterial Inhibitor

    Sodium 4-aminosalicylate dihydrate serves as an inhibitor of dihydrofolate reductase (DHFR) and is recognized for its antituberculous properties. This compound exhibits anti-inflammatory effects, making it a valuable tool in the study of inflammatory bowel disease (IBD). Moreover, it is characterized by its oral bioavailability, enhancing its applicability in various research settings.
  23. Bacterial Inhibitor

    Sparfloxacin is a fluoroquinolone antibiotic that primarily targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA replication. It exhibits broad-spectrum antibacterial activity, making it effective against a variety of Gram-positive and Gram-negative pathogens. Sparfloxacin is commonly used in research applications to study bacterial resistance mechanisms and evaluate new antibacterial strategies.
  24. Bacterial Inhibitor

    Streptomycin sulfate is an aminoglycoside antibiotic that inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. It exhibits potent antibacterial activity against a range of Gram-negative and some Gram-positive bacteria, making it useful in both clinical and research settings. This reagent is commonly employed in studies involving microbial resistance, antibiotic efficacy, and protein synthesis mechanisms.
  25. Antibiotic

    Sulfamerazine is a sulfonamide antibiotic that functions by inhibiting bacterial dihydropteroate synthase, thereby interfering with folate synthesis necessary for DNA replication. This compound demonstrates broad-spectrum antibacterial activity, making it valuable in the treatment of various bacterial infections. Sulfamerazine is commonly utilized in microbiological research to study resistance mechanisms and the pharmacodynamics of sulfonamide antibiotics.
  26. Bacterial Inhibitor

    Sulfamethazine is an antimicrobial agent that acts as a bacterial inhibitor, demonstrating permeability across the blood-brain barrier. It is commonly utilized in veterinary medicine to treat and prevent a variety of animal diseases, including gastrointestinal and respiratory tract infections. Regulatory standards set by China and the European Commission establish a maximum residue level of 100 μg/kg for Sulfamethazine in animal products, underscoring its significance in both therapeutic and safety assessments.
  27. Antibiotic Agent

    Sulfapyridine is a sulfonamide antibiotic agent primarily targeting dihydropteroate synthetase (DHPS) in Pneumocystis carinii, exhibiting an IC50 of 0.18 μM. It demonstrates significant antibacterial, anti-inflammatory, and anti-rheumatic properties, making it valuable for various research applications focused on infectious diseases and inflammatory conditions. This compound serves as an important tool in studies of bacterial resistance and therapeutic interventions.
  28. Antibiotics

    Sulfathiazole is an antibiotic with notable activity as an endocrine disruptor, primarily targeting the steroidogenic pathway by enhancing CYP19 activity in human adrenal cancer cells (H295R). This compound also upregulates the mRNA expression of CYP17, CYP19, and 3β-HSD, leading to increased production of 17-estradiol (E2). Additionally, sulfathiazole demonstrates endocrine-disrupting effects in aquatic organisms, such as the Japanese medaka fish, making it relevant for studies in environmental toxicology and endocrine disruption research.
  29. Sulfonamide Antibiotic

    Sulfadimethoxine is a sulfonamide antibiotic that inhibits bacterial growth by interfering with folic acid synthesis. This compound exhibits broad-spectrum antibacterial activity, making it effective against a variety of Gram-positive and Gram-negative pathogens. It is commonly utilized in research applications related to microbiology and pharmacology, particularly in the study of antibiotic resistance and the development of novel antimicrobial agents.
  30. Antibiotic Agent

    Thiamphenicol is a broad-spectrum antibiotic that operates by binding to the 50S ribosomal subunit, thereby inhibiting protein synthesis and exerting a bacteriostatic effect. This compound is effective against a wide range of Gram-negative and Gram-positive aerobic and anaerobic bacteria. It is commonly utilized in research applications related to antimicrobial resistance and the study of bacterial protein synthesis mechanisms.
  31. Antibacterial Agent

    Tinidazole is an orally available antibacterial agent belonging to the 5-nitroimidazole class, with selective activity against anaerobic bacteria and protozoa. This compound exhibits potent antimicrobial properties, making it useful in treating infections caused by susceptible organisms. Tinidazole is commonly employed in research focused on bacterial resistance mechanisms and the development of antiparasitic therapies.
  32. Antibiotic

    Toltrazuril is an antiprotozoal agent primarily targeting Coccidia parasites. It demonstrates effective inhibition of parasite growth and replication, making it a valuable tool for research involving coccidiosis and related infectious diseases. This compound is frequently utilized in studies assessing therapeutic approaches and drug efficacy against Coccidia infections in various organisms.
  33. Bacteriostatic Antibiotic

    Trimethoprim is a bacteriostatic antibiotic that primarily targets dihydrofolate reductase, inhibiting folate synthesis in bacteria. It exhibits activity against a broad spectrum of Gram-positive and Gram-negative aerobic organisms, making it valuable in the study of urinary tract infections, Shigellosis, and Pneumocystis pneumonia. Additionally, Trimethoprim has demonstrated potential in inhibiting Influenza A virus infection in chick embryos when used in combination with zinc.
  34. Antibiotic for Poultry

    Tylosin tartrate is a macrolide antibiotic derived from the fermentation of Streptomyces fradiae, primarily targeting Gram-positive bacteria. It exhibits strong antimicrobial activity, making it effective in veterinary applications, particularly for the treatment of bacterial dysentery and respiratory diseases in poultry, pigs, and cattle. Additionally, Tylosin tartrate is utilized as a feed additive to promote growth in livestock.
  35. Bacterial Inhibitor

    Urethane, also known as ethyl carbamate, is an ethyl ester of carbamic acid that acts as a bacterial inhibitor. It demonstrates the ability to suppress the growth of bacteria, protozoa, sea urchin eggs, and plant tissues in vitro. This compound is primarily utilized in studies examining microbial inhibition and growth regulation in various biological systems.
  36. Anti-bacterial Agent

    Valnemulin hydrochloride is an orally active truncated pleuromutilin antibiotic that inhibits bacterial protein synthesis by binding to peptidyl transferase in the 50S ribosomal subunit. This compound demonstrates significant antibacterial activity against Mycobacterium bovis, effectively reducing infection in experimental bovine models of Mycoplasma bovis. Additionally, Valnemulin hydrochloride reduces mortality associated with epidemic rabbit enteropathy while maintaining growth performance in rabbits, making it a valuable reagent for research in veterinary microbiology.
  37. Macrolide Antibiotic

    Acetylspiramycin is a macrolide antibiotic that demonstrates potent antibacterial activity against gram-positive bacteria. Its primary mechanism involves inhibition of splenic lymphocyte transformation induced by phytohemagglutinin (PHA) and lipopolysaccharide (LPS), while also reducing the procoagulant activity of macrophages. This compound is particularly valuable in research applications focused on combating parasitic infections and studying immune response modulation.
  38. Dianionic Cephem Antibiotic

    Ceftibuten dihydrate is a dianionic cephem antibiotic primarily targeting bacterial cell wall synthesis. It exhibits potent in vitro activity against a broad spectrum of gram-negative bacteria and select gram-positive pathogens. This compound is valuable for research applications involving antibiotic resistance studies and the investigation of bacterial infections.
  39. Cephalosporin Antibiotic

    Cefpirome sulfate is a cephalosporin antibiotic that targets penicillin-binding proteins, effectively inhibiting bacterial cell wall synthesis. This compound demonstrates bactericidal and growth-inhibitory activities against a broad spectrum of pathogens, including Gram-negative and Gram-positive bacteria, as well as certain anaerobic bacteria, including some strains that produce β-lactamase. Its ability to traverse cell membranes and the blood-brain barrier enhances its utility in various microbiological research applications.
  40. Bacterial Inhibitor

    Carbadox is a quinoxaline-di-N-oxide antibiotic that functions as a bacterial inhibitor. It is primarily used in veterinary medicine to control enteric infections in nursery-age pigs, enhancing feed efficiency and promoting overall health. Its antibacterial properties make it valuable for research applications focused on veterinary pharmacology and microbiology in the study of antibiotic efficacy and resistance mechanisms.
  41. Bacterial Inhibitor

    Meclocycline Sulfosalicylate Salt is a tetracycline antibiotic that acts as a bacterial inhibitor through the inhibition of protein synthesis. It exhibits broad-spectrum antibacterial activity, making it effective against various skin infections, including acne vulgaris. This reagent is valuable for research into antibiotic resistance and the mechanisms of bacterial infection.
  42. Antibiotic

    Fosfomycin tromethamine is a broad-spectrum antibiotic that acts by irreversibly inhibiting an early stage of bacterial cell wall synthesis. This compound effectively penetrates the blood-brain barrier and demonstrates significant antibacterial activity against various strains, including multidrug-resistant (MDR), extensively drug-resistant (XDR), and pan-drug-resistant (PDR) bacteria. It is utilized in research applications aimed at understanding bacterial resistance mechanisms and evaluating novel therapeutic strategies.
  43. Antibacterial Agent

    Pasiniazid is a complex formed by the combination of isoniazid and para-aminosalicylic acid in a 1:1 molar ratio, acting primarily as an antibacterial agent targeting Mycobacterium tuberculosis. Upon administration, Pasiniazid decomposes rapidly in the gastrointestinal tract, releasing isoniazid, which exhibits a bactericidal effect, while para-aminosalicylic acid prolongs the acetylation of isoniazid. This compound is valuable for research applications related to tuberculosis and the development of effective treatment regimens.
  44. D2R Antagonist

    Prochlorperazine dimaleate is an orally active dopamine D2 receptor (D2R) antagonist. It demonstrates notable anti-cancer activity in vitro against a range of cancer cell lines, with IC50 values of 6.4 μM for NOX1, 4.5 μM for NOX2, and 2.3 μM for NOX5. Additionally, prochlorperazine dimaleate exhibits antedesmosidic activity against the dengue virus (DENV). This compound is valuable for research aimed at understanding and treating conditions such as nausea, vomiting, migraine, and schizophrenia.
  45. Bacterial Inhibitor

    Saccharin is a non-caloric artificial sweetener that primarily exhibits bacteriostatic properties. It is recognized for its ability to inhibit bacterial growth and modulate the microbiome. This compound is utilized in various research applications aimed at studying microbial dynamics and the effects of sweeteners on bacterial populations.
  46. Cephem Antibiotic

    Cefcapene pivoxil hydrochloride hydrate is a cephalosporin antibiotic, primarily acting on bacterial cell wall synthesis. This orally active third-generation compound exhibits a broad spectrum of antibacterial activity, making it suitable for various microbiological research applications. Additionally, Cefcapene pivoxil hydrochloride hydrate shows potential as a therapeutic candidate in the study of palmoplantar pustulosis (PPP).
  47. Antibacterial Agent

    Flucloxacillin sodium is a beta-lactam antibiotic that primarily targets bacterial cell wall synthesis. It exhibits strong antibacterial activity against a range of gram-positive bacteria, including staphylococci, and is effective against some gram-negative strains. Flucloxacillin sodium is commonly utilized in research to investigate antibacterial resistance mechanisms, as well as in studies focused on the efficacy of antibiotic treatments.
  48. Antibiotic

    Cefetamet pivoxil hydrochloride is an oral third-generation cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits broad-spectrum antibacterial activity against various gram-positive and gram-negative pathogens. This compound is utilized in research applications focused on evaluating antibiotic efficacy and resistance mechanisms.
  49. Antibacterial Agent

    Cefathiamidine is a first-generation cephalosporin antibacterial agent targeting bacterial cell wall synthesis. It demonstrates a broad spectrum of antimicrobial activity against various susceptible bacterial strains. This reagent is utilized in the treatment of a range of infections, including respiratory, liver, sensory organ infections, urinary tract infections, endocarditis, and sepsis, making it valuable in both clinical settings and microbiological research.
  50. Anti-bacterial Agent

    Nonanoic acid is a naturally occurring saturated fatty acid that exerts its biological effects primarily through its antibacterial properties. It has been shown to significantly reduce bacterial translocation and enhance antibacterial activity, as well as notably increase the secretion of porcine β-defensins 1 (pBD-1) and pBD-2. This compound serves as a valuable tool in research focusing on bacterial resistance and host defense mechanisms.

Items 6201-6250 of 6342

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