Loratadine-d5-1 is a deuterated analog of Loratadine, which serves as a selective inverse agonist of peripheral histamine H1 receptors. It exhibits an IC50 of greater than 32 μM and has been shown to possess anti-dengue virus (DENV) activity. Additionally, Loratadine is capable of inhibiting the immunologic release of inflammatory mediators, making it a valuable tool for research in allergy and inflammation studies.
Loratadine-d5-1 is a deuterated analog of Loratadine, which serves as a selective inverse agonist of peripheral histamine H1 receptors. It exhibits an IC50 of greater than 32 μM and has been shown to possess anti-dengue virus (DENV) activity. Additionally, Loratadine is capable of inhibiting the immunologic release of inflammatory mediators, making it a valuable tool for research in allergy and inflammation studies.
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