Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
1-Methyl-4-nitroimidazole is an antibacterial agent that functions primarily through reduction by bacterial nitroreductases, leading to the generation of toxic derivatives. These derivatives induce DNA damage and inhibit bacterial nucleic acid synthesis, while also producing toxic superoxides that promote bacterial cell death. This compound demonstrates moderate in vitro activity against both bacterial and fungal pathogens and is applicable in research focused on skin infections, purulent infections, and urinary tract infections. -
Antifungal Agent
SPK-843 is a potent antifungal agent that demonstrates significant inhibitory activity against Aspergillus fumigatus (MIC 0.5 μg/mL), Aspergillus flavus (MIC 0.25 μg/mL), and Aspergillus niger (MIC 0.0625 μg/mL). This compound exhibits dose-dependent efficacy in murine models of pulmonary aspergillosis, making it valuable for studying therapeutic strategies for fungal infections. SPK-843 can be employed in various research applications related to antifungal drug development and fungal pathogenesis. -
Anti-Fungal Agent
1,6-Dihydroxy-2-chlorophenazine is a compound that exhibits weak anti-fungal and anti-yeast activity. Its mechanism involves interference with cellular processes in fungi, making it a candidate for research in antifungal drug development. This compound may be utilized in studies investigating the mechanisms of fungal infection and resistance, as well as in screening assays for new therapeutic agents. -
Antitumor Antibiotic
Glidobactin C is an antitumor antibiotic that exhibits significant antifungal activity against pathogenic fungi and yeast, particularly Candida albicans and Aspergillus fumigatus, with a minimum inhibitory concentration (MIC) of 0.8 μg/mL. This compound has demonstrated the potential to extend survival in murine models inoculated with leukemia P388 cells. Research applications include investigating its therapeutic efficacy in cancer and fungal infections, contributing to the development of novel treatments in these areas. -
Antifungal Agent
O-Acetylbenzeneamidinocarboxylic acid serves as an antifungal agent targeting various plant pathogenic fungi. This compound exhibits notable inhibitory activity, making it suited for research applications focused on understanding fungal infections and developing antifungal strategies in agricultural settings. Its effectiveness as a fungal metabolite positions it as a valuable tool in the study of plant pathology. -
Antifungal Agent
Eulicin is an antifungal agent primarily targeting fungal pathogens. It exhibits significant activity against both Gram-positive and Gram-negative bacteria and has demonstrated the ability to inhibit human immunodeficiency virus (HIV) infection and replication. Eulicin is derived from the genus Streptomyces, making it a valuable compound for research in microbial resistance and antiviral therapeutics. -
Antifungal Activity
4-Methyl-6,7-methylenedioxycoumarin is a coumarin derivative that displays significant antifungal activity. It demonstrates effectiveness against Pythium species, making it a valuable tool for research in antifungal applications. This compound is suitable for studies aiming to explore the mechanisms of antifungal resistance and the development of new antifungal agents. -
Antibiotic
2-Hydroxymethylclavam is a β-lactam antibiotic with a primary mechanism of inhibiting bacterial cell wall synthesis. This compound exhibits antifungal activity, particularly against plant pathogenic fungi. It can be utilized in research studies focused on antibiotic resistance and the development of antifungal therapies. -
Antimicrobial Agent
Streptothricin E is a potent antimicrobial agent with broad-spectrum antibacterial and antifungal properties. It exhibits effective inhibitory activity against various bacterial and fungal strains, making it valuable in microbiological research and therapeutic applications. Additionally, Streptothricin E has been shown to inhibit the PR-8 strain of influenza virus in tissue culture, highlighting its potential utility in virology studies. -
Diffusion Signaling Factor
Cis-11-Methyl-2-dodecenoic acid is a diffusion signaling factor (DSF) involved in quorum sensing (QS) within microbial and fungal communication systems. This compound plays a crucial role in regulating virulence and biofilm formation in several bacterial pathogens, making it a valuable tool for research on microbial interactions and pathogenesis. Its application extends to studies aimed at understanding the mechanisms of bacterial communication and the development of strategies to combat bacterial infections. -
Anti-Fungal Agent
Neosordarin is an effective antifungal agent that targets fungal pathogens, including Saccharomyces cerevisiae. It demonstrates potent inhibitory activity with an IC50 value ranging from 0.2 to 0.3 μg/mL. This compound is particularly valuable in research applications focused on understanding fungal resistance and developing antifungal therapies. -
Antifungal Antibiotic
PF-1163B is a potent antifungal antibiotic that targets fungal cell wall synthesis. It exhibits strong inhibitory activity against a range of pathogenic fungi, making it valuable for research into antifungal therapies and mechanisms of resistance. This compound can be utilized in studies aimed at understanding fungal pathogenesis and developing novel treatments for fungal infections. -
Antifungal Agent
Antifungal Agent 113 (compound 9a) is a potent compound targeting fungal and bacterial pathogens. It exhibits significant antifungal and antibacterial activity, specifically against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). This compound is valuable for research applications focused on combating resistant infections and exploring antifungal mechanisms. -
Antifungal Agent
Ascochitine is a polyketide-derived secondary metabolite that serves as a selective antifungal agent. It demonstrates broad-spectrum phytotoxicity and antimicrobial properties, making it a valuable tool in agricultural and chemical research applications focused on combating fungal pathogens. This compound can be utilized for studies investigating plant-fungal interactions and the development of antifungal strategies. -
Fungal Inhibitor
Kayahope is a potent fungal inhibitor that targets key enzymes involved in fungal cell wall biosynthesis. This compound demonstrates significant antifungal activity against various fungal pathogens, making it a valuable tool in the study of fungal infections and their treatment. Kayahope's utility extends to research applications in microbiology and pharmacology, aiding in the development of new antifungal therapies. -
Antibiotic
Lepiochlorin is an antibiotic metabolite derived from the Lepiota species of fungus, commonly associated with ant cultivation. This compound exhibits potent antifungal activity, making it an effective agent for preventing fungal contamination in various biological systems. Its unique mode of action and natural origin position Lepiochlorin as a valuable tool for research in microbial interactions and antifungal drug development. -
Anti-Fungal Agent
Haliangicin A is an anti-fungal agent targeting filamentous fungi and oomycetes. It demonstrates significant activity against a range of fungal pathogens, making it a valuable tool for studying fungal biology and developing antifungal strategies. Notably, Haliangicin A exhibits no antibacterial activity, which underscores its specificity in targeting fungal organisms. This compound is suitable for research applications focused on mycology and antifungal pharmacology. -
Staphylococcus aureus Inhibitor, Candida albicans Inhibitor
5,6,7,8-Tetramethoxyflavone is a flavonoid that acts as an inhibitor of *Staphylococcus aureus* and *Candida albicans*. This compound exhibits significant antibacterial and antifungal activities, making it valuable for research focused on microbial infections. Its ability to impede the growth of these pathogens supports its use in studies investigating therapeutic strategies against bacterial and fungal infections. -
Antibiotic
Polyoxin K is a nucleoside antifungal antibiotic that targets chitin synthesis in fungal cell walls. It exhibits potent activity against various fungal pathogens, making it particularly effective in managing rice sheath blight. This compound is valuable for research in fungal biology and exploring antifungal mechanisms for agricultural applications. -
Antifungal Agent
(E)-Isoeugenol acetate is a derivative of Eugenol known for its antifungal properties. This compound has demonstrated efficacy against various fungal strains, making it a valuable tool in mycology research and antifungal studies. Its applications include investigating mechanisms of action against fungal pathogens and exploring potential therapeutic uses in antimicrobial formulations. -
Anti-Fungal Agent
Phosmidosine is an anti-fungal agent that primarily targets the cell cycle mechanisms in eukaryotic cells. It has been shown to inhibit cell cycle progression and prevent morphological recovery in srcts-NRK cells, demonstrating its potential efficacy in fungal pathogenesis research. This compound is valuable for studying antifungal properties and elucidating the underlying biological processes in fungal cell growth and division. -
Fungal Inhibitor
Dactylfungin A is an α-pyrone-containing compound that functions as a potent antifungal agent, primarily targeting fungal cell processes. Isolated from Dactylaria parvispora, it exhibits significant inhibitory activity against various fungal strains. This compound is valuable for research applications focused on understanding fungal biology and developing antifungal therapies. -
Antibiotic
Mycoversilin is an antibiotic that primarily targets protein synthesis. Its biological activity includes the inhibition of skin fungi and phytopathogenic fungi, making it useful in research related to fungal infections. Mycoversilin is not effective against yeast or bacterial strains, focusing its action on specific fungal pathogens. This compound is suitable for studies investigating antifungal mechanisms and the development of novel treatments. -
Anti-Fungal Agent
Chivosazol A is an antifungal agent exhibiting potent activity against yeast and filamentous fungi. This compound demonstrates significant toxicity towards mammalian cells, making it a valuable tool for researchers investigating fungal infections and cellular responses to antifungal agents. Its efficacy in targeting diverse fungal species positions Chivosazol A for applications in pharmaceutical studies and the development of novel antifungal therapies. -
Anti-Fungal Agent
Enactin Ib is an anti-fungal agent derived from the strain of Streptomyces roseoviridis. It exhibits limited antifungal activity and can be used for research focused on the mechanisms of fungal resistance and the development of new antifungal therapies. Its unique structural properties may provide insights into the modification of antifungal compounds for enhanced efficacy. -
Antibiotic
Glidobactin A is an acyl peptide antibiotic that exhibits antifungal activity. It demonstrates effectiveness against Candida species, Aspergillus fumigatus, and Trichophyton, making it of interest in the study of fungal infections. This compound can be utilized in research applications focusing on antibiotic resistance and the development of antifungal therapies. However, it is noteworthy that Glidobactin A shows limited efficacy against Candida albicans M-9 infections in murine models. -
Polyene Macrolide Antibiotic
Trichomycin B is a polyene macrolide antibiotic derived from the fermentation products of Streptomyces hachijoensis. This compound demonstrates significant antibacterial efficacy against a range of fungi, yeasts, and the protozoan Trichomonas. Trichomycin B is valuable in research focused on antifungal mechanisms and the treatment of trichomoniasis infections, contributing to the understanding of antibiotic activity and resistance. -
Anti-Invasive Fungal Infection Compound
Fosmanogepix (tautomerism) is an orally active broad-spectrum anti-invasive fungal compound that targets the Gwt1 enzyme, essential for the proper localization of glycosylphosphatidylinositol-anchored mannoproteins in fungi. By inhibiting Gwt1, Fosmanogepix disrupts the localization of cell wall mannoproteins, leading to impaired cell wall integrity, inhibited biofilm and germ tube formation, and reduced fungal growth. This compound is valuable for researching invasive fungal infections and evaluating potential therapeutic interventions. -
Antibiotic
Bagougeramine B is an orally active nucleoside antibiotic that targets bacterial and fungal pathogens. It demonstrates significant antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as certain fungi. This compound is valuable for research in antibiotic efficacy and resistance mechanisms in microbial populations. -
Antimicrobial Agent
Epelmycin D is a potent antimicrobial agent with activity against both Gram-positive and Gram-negative bacteria, as well as Candida albicans. In addition to its antifungal and antibacterial properties, Epelmycin D demonstrates significant antileukemic activity against the L1210 cell line, surpassing the efficacy of Aclacinomycin. This compound is valuable for research applications focused on infectious disease and cancer therapeutics. -
Antifungal
(+)-β-Pinene is a natural enantiomer with demonstrated antifungal properties. Its primary mechanism involves disrupting the integrity of fungal cell walls, leading to compromised cellular function and viability. This compound is utilized in various biological research applications, particularly in studies focused on fungal pathogenesis and the development of antifungal agents. -
Pesticide/Fungicide
Triticonazole is a triazole fungicide that inhibits the biosynthesis of ergosterol by targeting the cytochrome P450 enzyme system in fungi. This compound exhibits broad-spectrum antifungal activity, making it effective in controlling various fungal pathogens in agricultural applications. Additionally, Triticonazole has been studied for its potential endocrine-disrupting effects, contributing to research in environmental toxicology and pesticide safety. -
CYP51 Inhibitor
Pipercroside A is a potent CYP51 inhibitor derived from Piper crocatum Ruiz & Pav. This compound exhibits significant antifungal activity, making it a valuable tool in studies of fungal infections and drug resistance mechanisms. Its role in inhibiting sterol biosynthesis positions Pipercroside A as a candidate for further investigation in antifungal therapeutic development. -
Antibiotic
Dehydrogriseofulvin is an antibiotic compound derived from Penicillium species, exhibiting inhibitory activity against Colletotrichum musae. It is characterized by a minimum inhibitory concentration (MIC) greater than 1 µg/mL, indicating its potency in combating fungal pathogens. Dehydrogriseofulvin is valuable for research applications focused on antifungal mechanisms and the study of mycological infections. -
Anti-Fungal Agent
Cystothiazole A is an antifungal agent that exhibits potent inhibitory activity against various fungal pathogens, including Candida albicans, Saccharomyces cerevisiae, and Aspergillus species, with minimum inhibitory concentrations (MIC) of 0.4 μg/mL, 0.1 μg/mL, and 1.6 μg/mL, respectively. Additionally, this compound demonstrates cytotoxic effects against human tumor cell lines, such as HPT-116 and K562, with MIC values of 130 ng/mL and 110 ng/mL, respectively. Cystothiazole A does not exhibit antibacterial activity. -
Anti-Fungal Agent
Fumifungin is an antifungal agent that demonstrates potent activity against a variety of fungal pathogens, including Cercospora, Cladosporium, Aspergillus niger, Penicillium digitatum, Trichophyton mentagrophytes, Alternaria, and Candida albicans. Its broad-spectrum efficacy makes it valuable for research applications focused on the treatment of fungal infections and understanding fungal biology. Fumifungin is essential for investigations aimed at elucidating mechanisms of antifungal resistance and developing new therapeutic strategies against fungal diseases. -
Fungal Inhibitor
Hyalodendrin is a fungal growth inhibitor that targets wood decay fungi, demonstrating significant inhibitory activity. This compound exhibits low phytotoxicity and has an acute toxicity (LD50) value of 75 mg/kg in mice, making it suitable for research applications in the study of fungal inhibition and plant health. Its unique properties make it an important reagent for investigating fungal resistance and developing environmentally friendly agricultural solutions. -
Fungal Inhibitor
Iodiconazole is a potent antifungal agent that targets fungal cell membrane synthesis. It exhibits significant inhibitory activity against a broad spectrum of pathogenic fungi, making it a valuable tool in antifungal research. This compound is particularly useful for studying fungal resistance mechanisms and the development of new therapeutic strategies against fungal infections. -
Antifungal Compound
Amycolatopsin B is a glycosylated polyketide macrolide with potent antifungal activity. Isolated from the soil isolate Amycolatopsis sp. MST-108494, it acts by inhibiting key cellular functions in fungal pathogens. This compound is valuable for research applications in mycology and the study of antifungal resistance mechanisms. -
Anti-Fungal Agent
Neoenactin A is a potent anti-fungal agent that demonstrates significant activity against both yeast-like and filamentous fungi. Its mechanism involves the disruption of fungal cell membrane integrity, leading to cell death. This compound is useful for researchers studying fungal pathogenesis, treatment strategies for fungal infections, and the development of novel antifungal therapeutics. -
Antibiotic
Merulidial is an antibiotic and cytotoxic agent characterized by its sesquiterpene dialdehyde structure. It effectively inhibits the germination of spores and hyphal growth in the wood-rotting basidiomycete Heterobasidion annosum and the saprophytic mold Cladosporium cucumerinum. Additionally, Merulidial demonstrates antibacterial and algicidal properties, along with the ability to inhibit DNA synthesis in ECA cells. Notably, it exhibits potent anticancer activity, with IC50 values of 20 μg/mL for ECA cells and 10 μg/mL for L1210 cells, making it a valuable candidate for further research in cancer and microbial therapeutics. -
Antifungal Antibiotic
BE-31405 is an antifungal antibiotic that targets pathogenic fungi. It demonstrates potent growth inhibition against various fungal strains, including Candida albicans, Candida glabrata, and Cryptococcus neoformans. Derived from the culture broth of Penicillium minioluteum and related fungal species, BE-31405 is notable for its selectivity, displaying no cytotoxicity towards mammalian cells. This compound is valuable for research applications focusing on antifungal therapies and the study of fungal pathogenicity. -
Antifungal Antibiotic
Pinselin is a nitrogen-containing heterocyclic antibiotic that demonstrates significant antifungal activity. It is particularly effective against yeast, making it valuable for research focused on fungal infections and antibiotic efficacy. This compound can be utilized in studies investigating mechanisms of resistance and in the development of novel antifungal therapies. -
Aflatoxin Production Inhibitor
Cyclo(L-leucyl-L-valyl) is an aflatoxin production inhibitor that targets the transcription of specific Aflatoxin-related genes in Aspergillus parasiticus, including aflR, hexB, pksL1, and dmtA. This compound is used to study the regulation of aflatoxin biosynthesis and its impact on fungal pathogenicity. It serves as an important tool in mycology and food safety research, particularly in understanding the molecular mechanisms behind mycotoxin production. -
Anti-Fungal Agent
Fulvoferruginin is an anti-fungal agent that demonstrates significant cytotoxicity against various fungal strains, particularly Paecilomyces varioti. This compound is of interest for research applications focused on fungal infections and the development of new antifungal therapies. Its unique properties make it a valuable tool in studying fungal pathogenesis and evaluating therapeutic efficacy. -
Antibiotic
Maltophilin is a broad-spectrum antifungal antibiotic that primarily targets fungal cell membranes, inhibiting their growth and viability. While effective against various fungal species, it has no antibacterial activity against Gram-positive and Gram-negative bacteria. This compound is suitable for research applications focused on understanding fungal infections and developing antifungal therapies. -
Anti-Fungal Agent
Formamicin is an antifungal agent that demonstrates broad-spectrum activity against plant pathogenic fungi. It effectively inhibits fungal growth, making it valuable for research applications focused on plant health and disease management. This compound may be utilized in studies examining fungal resistance mechanisms and strategies for crop protection. -
Wheat Fungicide
Silthiofam is a fungicide specifically targeting Gaeumannomyces graminis, the pathogen responsible for take-all disease in wheat. It exhibits strong efficacy in inhibiting fungal growth, thereby protecting wheat crops from significant yield loss. This compound is valuable for agricultural research focused on disease management and the development of effective crop protection strategies. -
SDH Inhibitor
SDH-IN-44 is a succinate dehydrogenase (SDH) inhibitor that demonstrates an IC50 of 12.5 μg/mL against Alternaria solani. This compound exhibits significant antifungal activity by inhibiting fungal mycelial growth, making it a valuable tool in the study of fungal infections. Research applications include understanding mechanisms of fungal pathogenicity and exploring therapeutic strategies for fungal diseases. -
Antimicrobial Agent
Piroctone is a potent hydroxypyridone antimicrobial agent primarily targeting fungal pathogens, particularly effective against Candida species. It inhibits hyphal induction in Candida albicans, contributing to its antifungal properties. Additionally, Piroctone efficiently chelates intracellular iron, inducing cytotoxic effects in neuroblastoma cells. This compound is applicable in antimicrobial research and studies focusing on neuroblastoma.
