Beclabuvir

Catalog No.: A21511

HCV NS5B RNA-dependent RNA polymerase inhibitor

Beclabuvir

Beclabuvir Chemical Structure

CAS NO. 958002-33-0

Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.

Availability: In stock

Package Price Qty
1 mg
$151.00
5 mg
$454.00
10 mg
$773.00
50 mg
$2,318.00
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Biological Activity

Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.16 mL 75.78 mL 151.55 mL
0.5 mM 3.03 mL 15.16 mL 30.31 mL
1 mM 1.52 mL 7.58 mL 15.16 mL
5 mM 0.3 mL 1.52 mL 3.03 mL

*The above data is based on the productmolecular weight 659.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21511
Actions Inhibitor
CAS No. 958002-33-0
Formula C36H45N5O5S
M. Wt 659.84
Purity >98%
Synonyms BMS-791325, BMS791325, BMS 791325
SMILES O=C(N1C2CCC1CN(C)C2)[[email protected]@]3(CN4C5=C(C6CCCCC6)C7=CC=C(C(NS(N(C)C)(=O)=O)=O)C=C47)[[email protected]](C8=CC(OC)=CC=C85)C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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