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Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Licoflavonol is a minor flavone derived from the roots of Glycyrrhiza uralensis, functioning as an inhibitor of the Salmonella type III secretion system (T3SS). This compound exhibits notable antibacterial activity, making it a valuable tool for researching Salmonella pathogenesis and the mechanisms of bacterial infection. Its targeted inhibition of T3SS offers potential applications in the development of antimicrobial strategies and the study of host-pathogen interactions. -
Bacterial Inhibitor
Glucuronic acid sodium functions primarily as a bacterial inhibitor, demonstrating notable anti-inflammatory properties. It supports the healing of ulcerative colitis by enhancing the intestinal barrier through the upregulation of tight junction proteins such as ZO-1 and Occludin. Additionally, Glucuronic acid sodium modulates gut microbiota composition by promoting beneficial bacterial populations while inhibiting pathogenic microbes, making it a valuable tool for research in gastrointestinal health and microbiome studies. -
Bacterial Inhibitor
Pinocembrin chalcone, known as 2',4',6'-Trihydroxychalcone, is a bacterial inhibitor derived from Helichrysum trilineatum. It activates AMP-activated protein kinase (AMPK), enhancing glucose tolerance while promoting fatty acid oxidation and reducing fat accumulation in the liver and skeletal muscles of high-fat diet-induced diabetic mice. This compound shows potential for research applications in gastric ulcer and diabetes studies, contributing to the understanding of metabolic regulation and bacterial infections. -
Bacterial Inhibitor
Guaijaverin is a bacterial inhibitor that functions as a urease inhibitor with an IC50 of 120 μM. Demonstrating antioxidant properties, it exhibits significant anti-Streptococcus mutans activity. This compound is valuable for research focused on bacterial inhibition and potential therapeutic applications in treating infections caused by Streptococcus species. -
Bacterial Inhibitor
Medicagenic acid, a potent bacterial inhibitor derived from the roots of Herniaria glabra, demonstrates significant fungistatic activity against various plant pathogens and human dermatophytes. This compound exhibits low enzyme inhibitory activity, specifically targeting xanthine oxidase, collagenase, elastase, tyrosinase, and cholinesterase. Medicagenic acid is valuable for research applications in studying antifungal resistance mechanisms and exploring potential therapeutic avenues for dermatological conditions. -
Bacterial Inhibitor
Tosylchloramide sodium trihydrate is a bacterial inhibitor that acts as a potent disinfectant. This reagent exhibits broad-spectrum antimicrobial activity, making it suitable for applications in laboratories, healthcare settings, and sanitation in commercial environments. Additionally, Tosylchloramide sodium trihydrate serves as a biocide in personal care products, including air fresheners and deodorants. -
Bacterial Inhibitor
Tolclofos-methyl is a bacterial inhibitor that functions as a broad-spectrum aromatic hydrocarbon fungicide. It exhibits potent activity against soil-borne and seed-borne fungal pathogens, effectively preventing seed decay and seedling blights. This compound is valuable in agricultural research for its ability to enhance seed treatment efficacy and promote plant health by mitigating fungal diseases. -
Bacterial Inhibitor
Fumagillol is a bacterial inhibitor with a primary role as a precursor to fumagillin. It exhibits significant antimicrobial activity and selectively inhibits angiogenesis, making it a valuable reagent for research in vascular biology and microbial pathology. Its utility extends to studies focused on the mechanisms of angiogenesis and the development of novel therapeutic strategies against microbial infections. -
Bacterial Inhibitor
Olanexidine hydrochloride is a monobiguanide compound with potent bactericidal activity, targeting bacterial cell membranes to disrupt membrane integrity. It demonstrates efficacy against a broad spectrum of both Gram-positive and Gram-negative bacteria. Notably, Olanexidine exhibits a bactericidal concentration of 109 μg/mL for Gram-positive bacilli, making it valuable in microbiological research and applications involving antimicrobial susceptibility testing. -
Penem β-Lactamase Inhibitor
BLI-489 hydrate is a penem β-lactamase inhibitor that effectively targets class A, class C, and certain class D β-lactamases. This compound demonstrates notable biological activity when used in combination with Piperacillin, showing efficacy against murine infections caused by pathogens expressing extended-spectrum β-lactamases, AmpC β-lactamases, and class D β-lactamases. BLI-489 hydrate is a valuable reagent for research into antibiotic resistance and the development of combination therapies. -
Bacterial Inhibitor
RPW-24 is a bacterial inhibitor that enhances the immune response of Caenorhabditis elegans, providing protection against bacterial infections. This compound demonstrates significant antibacterial activity, making it a valuable tool for studying host-pathogen interactions and immune modulation in nematodes. RPW-24 is applicable in research focusing on innate immunity and antimicrobial strategies in model organisms. -
Bacterial Inhibitor
(±)-Leucine, also known as DL-Leucine, is a stereoisomer of the amino acid leucine that acts as a bacterial growth inhibitor. It demonstrates significant antibacterial activity, inhibiting the growth of Escherichia coli HfrH by 92.08%. This compound is utilized in biochemical research for its potential applications in microbial control and as a dietary additive in various studies. -
β-lactamase Inhibitor
WCK-4234 is a potent β-lactamase inhibitor that effectively targets class A, C, and D β-lactamases. While lacking direct antibacterial activity, WCK-4234 enhances the efficacy of carbapenems such as imipenem and meropenem against Enterobacteriaceae possessing OXA-48/OXA-181 or KPC enzymes, as well as those exhibiting combinations of impermeability and AmpC or ESBL activity. This compound is particularly noteworthy for its ability to overcome resistance conferred by OXA-type carbapenemases, making it valuable for research in antibiotic resistance mechanisms. -
Bacterial Inhibitor
Hetacillin is a beta-lactam antibiotic that acts primarily by inhibiting bacterial cell wall synthesis. As a member of the aminopenicillin family, it is effective against a variety of gram-positive and some gram-negative bacteria. This reagent is commonly utilized in microbiological studies and antibiotic susceptibility testing, making it valuable for research on bacterial infections and resistance mechanisms. -
Bacterial β-glucuronidase Inhibitor
UNC10201652 is a potent inhibitor of bacterial β-glucuronidase, specifically targeting Loop 1 (L1) in gut microbiota, with an IC50 value of 0.117 μM for E. coli β-glucuronidase. This compound effectively blocks the processing of SN-38 glucuronide, predominantly in individuals with a high abundance of L1 GUS enzymes in their fecal microbiota. Its application is of particular interest in studying gut microbiome interactions and drug metabolism. -
Bacterial Inhibitor
3-O-Methylgalangin is a natural flavonoid derived from the rhizome of Alpinia officinarum, exhibiting significant antibacterial activity. This compound acts as a bacterial inhibitor and is also known to inhibit pancreatic lipase. Its properties make it a valuable tool for research in microbiology and metabolic studies. -
PRRSV/CD163 Inhibitor
PRRSV/CD163-IN-1 is a specific inhibitor of the interaction between porcine reproductive and respiratory syndrome virus (PRRSV) glycoproteins GP2a or GP4 and the CD163-SRCR5 domain. This compound is valuable for studying the mechanisms of PRRSV infection and the role of CD163 in viral entry. It is an essential tool for research aimed at understanding porcine reproductive and respiratory syndrome and developing potential therapeutic strategies. -
Bacterial Inhibitor
Nonacosane is a naturally occurring alkane derived from Baphia massaiensis, with demonstrated antibacterial activity. It exhibits weak inhibitory effects against various bacterial strains, including Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa, and Staphylococcus aureus. This compound can be utilized in research focused on bacterial resistance and the development of antibacterial agents. -
Bacterial Inhibitor
5-Desmethylsinensetin is a bacterial inhibitor derived from Artemisia princeps. This compound exhibits significant antiprotozoal activity, demonstrating IC50 values of 0.4 μg/mL against T. cruzi epimastigotes and 75.1 μg/mL against trypomastigotes. It serves as a valuable tool for research into protozoan infections and potential therapeutic applications. -
Bacterial Inhibitor
Salannin is a limonoid compound derived from the seed oil of Azadirachta indica, acting primarily as a bacterial inhibitor. It exhibits significant antibacterial activity against both Gram-positive and Gram-negative bacteria, making it a valuable reagent in microbiological research. Additionally, Salannin demonstrates antiulcer and spermicidal properties, supporting its potential applications in pharmacological studies and therapeutic development. -
Bacterial Inhibitor
2-Mercaptopyridine N-oxide sodium is a bacterial inhibitor targeting Mycobacterium tuberculosis. It exhibits a bactericidal effect with a minimum inhibitory concentration (MIC90) of 7.20 μM against the standard strain H37Rv (ATCC 27294). This compound, along with its complexes with iron, gallium, and bismuth, demonstrates promising anti-tuberculosis activity, indicating its potential utility in the treatment of tuberculosis. -
Bacterial Inhibitor
4-Ethoxyphenol is a natural bacterial inhibitor derived from the marine gorgonian-associated bacterium Bacillus amyloliquefaciens SCSIO 00856. This compound exhibits significant antilarval activity, demonstrating an EC50 value of 24.1 μg/mL against Bacillus amphitrite larvae. Its properties make it a valuable tool for research applications in microbiology and biopesticide development. -
Bacterial Inhibitor
Rubrofusarin is a polyketide pigment derived from Fusarium graminearum, known for its antibacterial properties. This compound exhibits significant biological activity, including anticancer and antioxidant effects, and has been shown to alleviate depressive symptoms induced by chronic restraint stress through the PI3K/Akt signaling pathway. Rubrofusarin serves as a valuable tool in research applications focused on bacterial inhibition and the exploration of therapeutic strategies for stress-related disorders. -
Bacterial Inhibitor
N-Butanoyl-DL-homoserine lactone (Rac-C4-HSL) functions as a bacterial inhibitor by interfering with quorum sensing mechanisms. This racemic mixture includes both N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone, the latter being significant in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone exhibits antibacterial activity by inhibiting biofilm formation, particularly in Pseudomonas aeruginosa, making it valuable for research in bacterial communication and biofilm-related studies. -
Parasite Inhibitor
Hexyl gallate is an alkyl ester derivative of gallic acid that acts as a potent inhibitor of Plasmodium falciparum, exhibiting significant antimalarial activity with an IC50 of 0.11 mM. Additionally, it demonstrates antibacterial properties by inhibiting the production of virulence factors such as rhamnolipid and pyocyanin through the inhibition of the RhlR regulatory protein. This compound is valuable for research in parasitic infections and the development of new therapeutic agents. -
β-lactamase Inhibitor
FPI-1523 sodium is a potent β-lactamase inhibitor targeting CTX-M-15 and OXA-48, with dissociation constants (Kd) of 4 nM and 34 nM, respectively. Additionally, it inhibits penicillin-binding protein 2 (PBP2) with an IC50 of 3.2 μM. FPI-1523 sodium demonstrates significant antimicrobial activity, making it a valuable reagent in the study of antibiotic resistance and the development of novel antimicrobial therapies. -
Bacterial Inhibitor
JPD447 is a potent inhibitor of the enzyme UppS, which plays a critical role in bacterial cell wall biosynthesis. By targeting this enzyme, JPD447 enhances the efficacy of β-lactam antibiotics, making it a valuable tool in combatting bacterial infections. Its application in research focuses on understanding antibiotic resistance mechanisms and improving antibiotic therapeutic strategies. -
Bacterial Inhibitor
4-Chloroquinaldine is a bacterial inhibitor that targets various bacterial species, demonstrating significant antibacterial activity. This compound serves as an important intermediate in chemical synthesis and research applications aimed at exploring antibiotic development and mechanisms of bacterial resistance. Its utility in microbiological studies makes it a valuable reagent for researchers in the field. -
Bacterial Inhibitor
Picloxydine is a heterocyclic biguanide that serves as a bacterial inhibitor. It exhibits significant antibacterial and antiplaque activity, making it useful in various research applications aimed at understanding microbial growth and infection control. This compound can be applied in studies related to dental hygiene and the prevention of bacterial biofilms. -
HIV Inhibitor
Ilimaquinone is a marine sponge-derived compound that functions as an HIV inhibitor. It exhibits anti-HIV activity along with anti-inflammatory, antimicrobial, and anticancer properties, primarily through the GADD153-mediated pathway. Additionally, Ilimaquinone has been shown to induce vesiculation of the Golgi apparatus, making it a valuable tool for research on viral infections and cellular mechanisms. -
Bacterial Inhibitor
LolCDE-IN-2 is a potent inhibitor of the LolCDE protein complex, targeting bacterial lipid transport. It demonstrates significant antibacterial activity against E. coli MG1655, with a minimum inhibitory concentration (MIC) of 2 μg/ml. This compound is valuable for research applications focused on bacterial pathogenesis and antibiotic resistance mechanisms. -
Bacterial Inhibitor
Enterocin K1 is a ribosomally synthesized peptide that functions as a bacteriocin, specifically targeting Enterococcus faecalis through the Eep protein on the bacterial membrane. This compound exhibits significant antibacterial activity against vancomycin-resistant Enterococcus (VRE). Enterocin K1 is primarily utilized in research focusing on VRE infections and the mechanisms of microbial resistance, making it a valuable tool in the development of novel therapeutic strategies. -
β-Lactamase Inhibitor
Metallo β-lactamase ligand 1 is an established class B β-lactamase inhibitor that targets metallo-β-lactamases, enzymes responsible for antibiotic resistance. This compound exhibits significant antibacterial activity, making it a useful tool in combating infections caused by β-lactamase-producing bacteria. It is particularly valuable in research focused on developing new antimicrobial strategies and understanding the mechanism of β-lactamase-mediated resistance. -
Bacterial Inhibitor
Fmoc-Tpi-OH is a biologically active amino acid that functions as a building block for the synthesis of antimicrobial peptide mimetics. Its unique structure allows for the development of compounds with potential antibacterial properties. This reagent is essential for research applications focused on peptide chemistry, drug design, and the exploration of new antimicrobial therapies. -
Bacterial Inhibitor
Isopsoralenoside is a benzofuran glycoside derived from Psoralea corylifolia, functioning primarily as a bacterial inhibitor. This compound exhibits estrogen-like activity, promotes osteoblastic proliferation, and demonstrates antitumor effects. Isopsoralenoside's antibacterial properties make it a valuable tool for research applications aimed at exploring microbial inhibition and associated biological processes. -
Bacterial Inhibitor
Bixafen is a pyrazole fungicide that acts as a succinate dehydrogenase inhibitor, effectively targeting and inhibiting bacterial pathogens in cereal crops. Its broad-spectrum activity makes it a valuable tool in agricultural research, helping to elucidate mechanisms of pathogen resistance and manage crop health. Bixafen's specific inhibition of succinate dehydrogenase contributes to its efficacy in various fungicidal applications. -
Bacterial Division Inhibitor
Divin, a bacterial division inhibitor, acts as a potent chelator of iron, leading to a bacteriostatic effect against both Gram-negative and Gram-positive bacteria. This compound disrupts the assembly of late division proteins, interferes with peptidoglycan remodeling at the division site, and inhibits cytoplasmic compartmentalization. Divin is valuable for research applications focused on understanding bacterial cell division mechanisms and developing new antibacterial strategies. -
Bacterial Inhibitor
Licoricone is a flavonoid derived from licorice that serves as a bacterial inhibitor. It demonstrates significant anti-Helicobacter pylori activity against both clarithromycin- and amoxicillin-resistant strains, as well as four clarithromycin- and amoxicillin-sensitive strains. This compound is valuable for research focusing on bacterial resistance and studies aimed at developing new therapeutic strategies against H. pylori infections. -
Bacterial Inhibitor
Nornidulin is a depsidone derived from Aspergillus nidulans, exhibiting significant antibacterial activity against Mycobacterium tuberculosis and Mycobacterium ranoe, as well as antifungal effects against Trichophyton tonsurans and Microsporum audouini. Additionally, it demonstrates potent inhibition of methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 2 μg/mL. Furthermore, Nornidulin displays cytotoxicity in MOLT-3 cells with an IC50 value of 35.7 μM, while exhibiting lower toxicity against HuCCA-1, HepG2, and A549 cell lines. -
β-lactamase Inhibitor
Brobactam sodium is a potent synthetic β-lactamase inhibitor that effectively targets various β-lactamase enzymes. This compound exhibits broad-spectrum antibacterial activity, making it a valuable tool for enhancing the efficacy of β-lactam antibiotics. Brobactam sodium is primarily utilized in research applications aimed at understanding antibiotic resistance mechanisms and developing new therapeutic strategies against resistant bacterial strains. -
Bacterial Inhibitor
3-CPs is a serotype capsular polysaccharide that inhibits antibody-mediated bacterial killing. By interfering with the immune response, it effectively reduces the phagocytosis of encapsulated bacteria. This compound is valuable for studying bacterial pathogenesis and the mechanisms of immune evasion. 3-CPs can inform research on vaccine development and therapeutic strategies aimed at combating encapsulated bacterial infections. -
Heat-inactivated Bacterial Luciferases Inhibitor
2-Nonanone is a ketone compound that inhibits the DnaKJE-ClpB bichaperone-dependent refolding of heat-inactivated bacterial luciferases. By interacting with hydrophobic segments of heat-inactivated substrates, it competes with chaperones such as IbpAB. This compound is valuable for research into bacterial infections and the mechanisms of chaperone-mediated protein refolding. -
Parasite Inhibitor
Hydroxymetronidazole, a metabolite of Metronidazole, functions primarily as an inhibitor of parasitic infections. This nitroimidazole derivative exhibits significant antibacterial and antiprotozoal activities, making it valuable in research applications related to bacterial and protozoal diseases. It is particularly useful for studying conditions such as swine dysentery, as well as genital trichomoniasis in cattle, contributing to a better understanding of these veterinary health issues. -
Bacterial Inhibitor
Ethyl Orsellinate is a lichen-derived metabolite and a derivative of lecanoric acid, primarily acting as a bacterial inhibitor. It exhibits notable antiproliferative and antitumor activities, making it useful in cancer research. The compound demonstrates significant cytotoxicity against A. salina, with an LC50 of 495 μM, indicating its potential as a bioactive agent in the study of microbial and tumor biology. -
Bacterial Inhibitor
EcMetAP1-IN-1 is a selective inhibitor of Escherichia coli methionine aminopeptidase 1 (MetAP1), a key enzyme involved in protein maturation. By obstructing the enzymatic activity of MetAP1, this compound effectively disrupts bacterial growth and protein synthesis, making it a valuable tool for research focused on bacterial infections and antibiotic development. Its specificity towards MetAP1 further positions EcMetAP1-IN-1 as a potential candidate for studying the mechanistic roles of methionine aminopeptidases in pathogenic bacteria. -
Bacterial Inhibitor
Urolithin M6 is a polyphenolic compound primarily recognized for its role as a bacterial inhibitor. This metabolite, synthesized through intestinal microbial metabolism, exhibits potential antioxidant properties and may function as an analogue to tannic acid compounds. Urolithin M6's production in humans necessitates the presence of specific bacterial 3-dehydroxylase activity, unveiling a novel pathway for its biotransformation. The metabolic profile of Urolithin M6 can aid in stratifying individuals for research aimed at elucidating its implications in health and disease. -
Bacterial Inhibitor
Methyl octanoate acts as a bacterial inhibitor and is recognized for its role in antimicrobial activity. This compound has applications in food preservation and can be studied for its effects on microbial growth inhibition. Additionally, it serves as a volatile aroma component in various beverages, including persimmon wine, making it of interest in both food science and microbiology research. -
Bacterial Inhibitor
NSC-79887 is a potent nucleoside hydrolase inhibitor that demonstrates significant activity against Bacillus anthracis. This compound serves as a promising candidate for biological testing and further development aimed at countering bacterial infections. Additionally, its pharmacokinetic profile suggests that all physicochemical parameters fall within acceptable ranges, indicating potential suitability for human use. -
Bacterial Inhibitor
Surgumycin is a bacterial inhibitor that exhibits notable antimicrobial activity. Its mechanism involves disrupting essential cellular processes in bacteria, making it a valuable tool for studying bacterial infections and resistance mechanisms. Surgumycin is particularly useful in research applications focused on antibiotic development and the exploration of microbial pathogenesis. -
Bacterial Inhibitor
LL-BM123α is a bacterial inhibitor derived from Nocardia sp., with a primary mechanism of action targeting Gram-negative bacteria. This compound demonstrates moderate antimicrobial activity, making it a valuable tool in research focused on bacterial infections and antibiotic resistance. LL-BM123α can be utilized in studies aimed at understanding the efficacy of novel antibiotics and developing strategies for overcoming bacterial resistance.
