Fig. 1 · Structure
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FPI-1523 sodium
Cat. No.
A48309
CAS
1452459-52-7
β-lactamase Inhibitor
FPI-1523 sodium is a potent β-lactamase inhibitor targeting CTX-M-15 and OXA-48, with dissociation constants (Kd) of 4 nM and 34 nM, respectively. Additionally, it inhibits penicillin-binding protein 2 (PBP2) with an IC50 of 3.2 μM. FPI-1523 sodium demonstrates significant antimicrobial activity, making it a valuable reagent in the study of antibiotic resistance and the development of novel antimicrobial therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1452459-52-7 |
| Applications | β-lactamase Inhibitor |
| Formula | C9H13N4NaO7S |
| Molecular Weight | 344.27 |
| SMILES | CC(NNC([C@H]1[N@@]2C(N([C@H](CC1)C2)OS(=O)(O[Na])=O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.