BLI-489 hydrate is a penem β-lactamase inhibitor that effectively targets class A, class C, and certain class D β-lactamases. This compound demonstrates notable biological activity when used in combination with Piperacillin, showing efficacy against murine infections caused by pathogens expressing extended-spectrum β-lactamases, AmpC β-lactamases, and class D β-lactamases. BLI-489 hydrate is a valuable reagent for research into antibiotic resistance and the development of combination therapies.
BLI-489 hydrate is a penem β-lactamase inhibitor that effectively targets class A, class C, and certain class D β-lactamases. This compound demonstrates notable biological activity when used in combination with Piperacillin, showing efficacy against murine infections caused by pathogens expressing extended-spectrum β-lactamases, AmpC β-lactamases, and class D β-lactamases. BLI-489 hydrate is a valuable reagent for research into antibiotic resistance and the development of combination therapies.
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