MK-3402 is a potent metallo-β-lactamase inhibitor that exhibits IC50 values of 0.53 nM, 0.25 nM, and 0.169 nM against enzymes IMP-1, NDM-1, and VIM-1, respectively. This compound enhances the efficacy of beta-lactam antibiotics and is valuable in bacterial research, particularly in studies focused on combating antibiotic resistance. MK-3402's strong inhibitory properties make it a critical tool for investigating metallo-β-lactamase-mediated resistance mechanisms.
MK-3402 is a potent metallo-β-lactamase inhibitor that exhibits IC50 values of 0.53 nM, 0.25 nM, and 0.169 nM against enzymes IMP-1, NDM-1, and VIM-1, respectively. This compound enhances the efficacy of beta-lactam antibiotics and is valuable in bacterial research, particularly in studies focused on combating antibiotic resistance. MK-3402's strong inhibitory properties make it a critical tool for investigating metallo-β-lactamase-mediated resistance mechanisms.
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