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Catalog No.
Product Name
Application
Product Information
Product Citation
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DCPS inhibitor
RG3039 (PF-06687859) is orally bioavailable, brain-penetrant small molecule that has been shown to be an inhibitor of the mRNA decapping enzyme, DcpS. -
Alpha-galactosidase inhibitor
Deoxygalactonojirimycin Hydrochloride is a potent and selective Alpha-gal A (Alpha-galactosidase) inhibitor. -
OSC Inhibitor
Ro 48-8071 is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity. -
NQO1 inhibitor
Dicoumarol is a competitive NADH quinone oxidoreductase (NQO1) inhibitor. -
cholinephosphotransferase inhibitor
Meclofenoxate HCl is an anti-aging drug used to treat the symptoms of senile dementia and Alzheimer's disease, and also inhibits the activity of cholinephosphotransferase. -
c-Fos inhibitor
T-5224 is a selective inhibitor of c-Fos/activator protein-1.- Kamata Y, .et al. , J Dermatol Sci, 2018, Apr 23. pii: S0923-1811(18)30186-5 PMID: 29730173
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SE inhibitor
NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway. -
SE inhibitor
NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway.- Gia-Buu Tran, .et al. , Cancer Res, 2023, Apr 14;CAN-22-3450 PMID: 37057874
- Weber RA, .et al. , Mol Cell, 2020, Feb 6;77(3):645-655 PMID: 31983508
- Garcia-Bermudez J, .et al. , Nature, 2019, Feb 13 PMID: 30760928
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MyD88 dimerization Inhibitor
ST 2825 is a MyD88 pharmacologic inhibitor.- Bernard Kan, .et al. , Nat Commun, 2018, 9: 4822 PMID: 30446641
- Shira Dishon, .et al. , Sci Rep, 2018, 8: 9476 PMID: 29930295
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TPA/PMA inhibitor
Cyclosporin H is a TPA/PMA inhibitor and a selective inhibitor of formyl peptide receptors (Ki = 0.1 uM). -
Cell adhesion inhibitor
K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1beta or TNF-alpha. -
DNA repair inhibitor
KRX-0402 is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin?€?s lymphoma. -
polyamine synthesis inhibitor
Sardomozide is a second-generation polyamine synthesis inhibitor, which inhibits the activity of the polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (SAMDC). -
PPCE inhibitor
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopeptidase (PPCE) inhibitor. -
Prolyl endopeptidase inhibitor
Y-29794 oxalate, inhibitor of prolyl endopeptidase, is a serine peptidase that may be implicated in the biosynthesis of amyloid β-peptide. -
Proprotein convertases inhibitor
Decanoyl-RVKR-CMK is a selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases. -
TPPII inhibitor
Butabindide oxalate is a selective and potent inhibitor of TPPII (tripeptidyl peptidase II). -
furin inhibitor
Hexa-D-arginine is a inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 uM for furin, PACE4 and PC1 respectively). -
SSAO/VAP-1 inhibitor
PXS-4728A is a very potent and highly selective compound in development for the treatment of cardiometabolic diseases like the liver-related disease Nonalcoholic Steatohepatitis (NASH). -
Fibrillogenesis inhibitor
Eprodisate is an orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis. -
Stemness kinase inhibitor
Amcasertib (BBI503), a first-in-class cancer stemness kinase inhibitor, is claimed to inhibit Nanog and other CSC pathways by targeting kinases with potential anticancer activity. -
LOXL2 inhibitor
LOXL2-IN-1 HCl is a selective LOXL2 inhibitor with an IC50 of 126 nM.
