Others

Sapacitabine is an orally bioavailable pyrimidine analogue prodrug with potential antineoplastic activity.

Halofuginone is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities.

Diosmetin is an O-methylated flavone, a chemical compound that can be found in the Caucasian vetch.

Ribitol is a crystalline pentose alcohol formed by the reduction of ribose.

Nobiletin is a chemical compound. It is an O-methylated flavone, a flavonoid isolated from citrus peels like in tangerine. Nobiletin was found to have anti-inflammatory and anti-tumor invasion, proliferation, and metastasis in vitro and in vivo. Nobiletin was also found to potentially inhibit cartilage degradation.

Betamethasone is a potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.

Rutin is one of the phenolic compounds found in the invasive plant species Carpobrotus edulis and contributes to the antibacterial and antioxidant properties of the plant

Theobromine(3,7-Dimethylxanthine) is a xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension.

Ioversol is low osmolality, nonionic, radiographic contrast agent.

Iopamidol is a non-ionic, water-soluble radiographic contrast agent.

Cefdinir is a third generation oral cephalosporin antibiotic.

Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic (anti-itching drug).

Oxacillin sodium monohydrate is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.

Pristinamycin is an antibiotic used primarily in the treatment of staphylococcal infections, and to a lesser extent streptococcal infections.

Meropenem is a β-lactam antibiotic of the carbapenem subclass that has been shown to inhibit penicillinase-negative, -positive and methicillin-susceptible staphylococci.

Vancomycin is a glycopeptide antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive bacteria

Rifapentine is an antibiotic drug used in the treatment of tuberculosis.

5-BrdU is a synthetic thymidine analog; incorporated into DNA during replication. Used in assays for cell proliferation.

Dihydroartemisinin is the active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself. It is a semi-synthetic derivative of artemisinin and is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs.

Paroxetine is an antidepressant drug of the SSRI type.

Ecdysone is a steroidal prohormone of the major insect molting hormone 20-hydroxyecdysone, which is secreted from the prothoracic glands.

Haematoxylin is extracted from the heartwood of the logwood tree.When oxidized it forms haematein, a compound that forms strongly coloured complexes with certain metal ions, the most notable ones being Fe(III) and Al(III) salts. Metal-haematein complexes are used to stain cell nuclei prior to examination under a microscope.

Zanamivir is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus.

Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.

Sinomenine(Cucoline) is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis.

Tirapazamine is a bioreductive, anti-neoplastic, anti-cancer agent that is selectively toxic to cells under hypoxic conditions.

AdipoRon is a novel small-molecule AdipoR agonist; binds to both AdipoR1(Kd= 1.8 uM) and AdipoR2(Kd=3.1 uM). IC50 value: 1.8/3.1 uM(AdipoR1/2, Kd)

Osthole(Osthol) is a type of coumarin.

3-Indolebutyric acid is a plant hormone in the auxin family and is an ingredient in many commercial horticultural plant rooting products.

4-Methylumbelliferone is a selective inhibitor of Hyaluronan (HA) synthesis which is thought to function as an inhibitor via the depletion of UDP-glucuronic acid, the common substrate for HA synthesis.

5-Aminolevulinic acid hydrochloride is a naturally occurring amino acid; precursor of tetrapyrroles in the biosynthesis of chlorophyll and heme.

7-Aminocephalosporanic acid is the core chemical structure for the synthesis of cephalosporin antibiotics and intermediates.

Acarbose is an anti-diabetic drug used to treat type 2 diabetes mellitus and, in some countries, prediabetes.

Acetanilide is used as an inhibitor in hydrogen peroxide and is used to stabilize cellulose ester varnishes.

Acitazanolast is an active metabolite of tazanolast and anti-allergic drug.

Aesculin is a glucoside that naturally occurs in the horse chestnut (Aesculus hippocastanum). It is used in a microbiology laboratory to aid in the identification of bacterial species (especially Enterococci and Listeria).

Alfacalcidol is an analogue of vitamin D.Alfacalcidol has a weaker impact on calcium metabolism than calcitriol, while having more potent effects on parathyroid hormone levels and the immune system, including regulatory T cells.

Aminocaproic acid is used to treat excessive postoperative bleeding, especially after procedures in which a great amount of bleeding is expected,

Amygdalin is a glycoside initially isolated from the seeds of the tree Prunus dulcis. Amygdalin induces apoptosis through regulation of Bax and Bcl-2 expressions in human DU145 and LNCaP prostate cancer cells.

Azalomycin-B is a macrolide antibiotic produced by Streptomyces hygroscopicus.

Beta Carotene is a strongly-coloured red-orange pigment abundant in plants and fruits. It is a precursor (inactive form) of vitamin A.

Biapenem is a carbapenem antibiotic. It has in vitro activity against anaerobes.

Bilobalide, a biologically active terpenic trilactone (terpinoid), derived from geranylgeranyl pyrophosphate (GGPP) is an inducer of cytochrome P450 enzymes CYP3A1 and CYP1A2. May contain properties to stop apoptosis activation of the phosphatidylinositol 3-Kinase pathway in SH-SY5Y cells.

Bimatoprost is a prostaglandin analog/prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension

Biochanin A is an antiproliferative and anti-inflammatory agent that inhibits iNOS expression and lipopolysacharide (LPS)-induced nitric oxide production in macrophages. Additionally, Biochanin A displays the ability to block phosphorylation of IκBα and p38 MAPK, which prevents NF-κB activation. Furthermore, Biochanin A has been observed to suppress IL-6, IL-1β, and TNF-α production.

BTZ043 (BTZ038, BTZ044) inhibits decaprenylphosphoryl-β-d-ribose 2?-epimerase, which is an enzyme which produces the cell wall of the pathogenic bacterium Mycobacterium tuberculosis.

Bumetanide is a loop diuretic of the sulfamyl category to treat heart failure.

Busulfan is a cell cycle non-specific alkylating antineoplastic agent, in the class of alkyl sulfonates.

Butylscopolamine BR is an orally available bromide salt form of butylscopolamine which is a peripherally acting antimuscarinic, anticholinergic agent.

Caffeic acid is an organic compound that is classified as hydroxycinnamic acid.