LL-37 amide is an antimicrobial peptide that selectively targets the formyl peptide receptor-like FPRL1. It demonstrates significant bactericidal activity against periodontal pathogens with an ED99 value of 8.5-8.7 μg/mL by inducing immune cell chemotaxis and disrupting bacterial cell membranes. Additionally, LL-37 amide modulates inflammatory responses by inhibiting the release of pro-inflammatory factors such as TNF-α and promotes angiogenesis. Its amidation modification enhances stability and reduces serum sensitivity. This reagent is valuable for research in infection-related diseases, including periodontal disease, deep tissue injuries, and wound healing.
LL-37 amide is an antimicrobial peptide that selectively targets the formyl peptide receptor-like FPRL1. It demonstrates significant bactericidal activity against periodontal pathogens with an ED99 value of 8.5-8.7 μg/mL by inducing immune cell chemotaxis and disrupting bacterial cell membranes. Additionally, LL-37 amide modulates inflammatory responses by inhibiting the release of pro-inflammatory factors such as TNF-α and promotes angiogenesis. Its amidation modification enhances stability and reduces serum sensitivity. This reagent is valuable for research in infection-related diseases, including periodontal disease, deep tissue injuries, and wound healing.
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