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CHRG01

Catalog No.: A48952
Bioactive Peptide
CHRG01 is a bioactive peptide derived from the C-terminal amino acids 54 to 67 of human β-defensin 3 (hBD3), with all cysteine residues substituted with serine to eliminate disulfide bonding. This modification preserves the peptide's antimicrobial properties while enhancing its stability. CHRG01 exhibits electrostatic-dependent antimicrobial activity, making it a valuable tool for research applications involving antimicrobial peptides and immune response studies.
CHRG01 646038-39-3 Bioactive Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCHRG01 is a bioactive peptide derived from the C-terminal amino acids 54 to 67 of human β-defensin 3 (hBD3), with all cysteine residues substituted with serine to eliminate disulfide bonding. This modification preserves the peptide's antimicrobial properties while enhancing its stability. CHRG01 exhibits electrostatic-dependent antimicrobial activity, making it a valuable tool for research applications involving antimicrobial peptides and immune response studies.
Product Information
Catalog NumA48952
FormulaC66H128N30O20
Molecular Weight1661.91
CAS Number646038-39-3
SequenceLys-Ser-Ser-Thr-Arg-Gly-Arg-Lys-Ser-Ser-Arg-Arg-Lys-Lys
Sequence shorteningKSSTRGRKSSRRKK
SMILES[C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCCN)N)=O)CO)=O)CO)=O)[C@@H](C)O)=O)CCCNC(=N)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CO)=O)CO)=O)CCCNC(=N)N)=O)(C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CCCCN)=O)CCCNC(=N)N
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