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Macropin

Catalog No.: A49104
Antimicrobial Peptide
Macropin (MAC-1 peptide) is an antimicrobial peptide derived from the venom of the solitary bee Macropis fulvipes. It demonstrates significant antibacterial activity against both Gram-positive and Gram-negative bacteria and exhibits antifungal properties as well as moderate hemolytic activity against human erythrocytes. Macropin serves as a valuable reagent for research focused on anti-infective therapeutics and the study of host-pathogen interactions.
Macropin 1382853-39-5 Antimicrobial Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMacropin (MAC-1 peptide) is an antimicrobial peptide derived from the venom of the solitary bee Macropis fulvipes. It demonstrates significant antibacterial activity against both Gram-positive and Gram-negative bacteria and exhibits antifungal properties as well as moderate hemolytic activity against human erythrocytes. Macropin serves as a valuable reagent for research focused on anti-infective therapeutics and the study of host-pathogen interactions.
Product Information
Catalog NumA49104
FormulaC68H121N17O13S
Molecular Weight1416.86
CAS Number1382853-39-5
SequenceGly-Phe-Gly-Met-Ala-Leu-Lys-Leu-Leu-Lys-Lys-Val-Leu-NH2
Sequence shorteningGFGMALKLLKKVL-NH2
SMILES[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)C(C)C)=O)CCCCN)=O)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CC1=CC=CC=C1)NC(CN)=O)=O)=O)CCSC)=O)C)=O)CC(C)C)=O)CCCCN)=O)CC(C)C)=O)CC(C)C)=O)CCCCN
SynonymsMAC-1 peptide
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