BTM-P1

Catalog No.: A49033
Antimicrobial Peptide
BTM-P1 is an antimicrobial peptide that primarily targets bacterial membranes, demonstrating potent antibacterial activity against both Gram-positive and Gram-negative bacteria. Its mechanism involves the formation of ion-permeable channels in the inner mitochondrial membrane, leading to disruptions in mitochondrial energy processes. BTM-P1 is suitable for research applications focused on understanding antimicrobial mechanisms and investigating the potential therapeutic use of peptide-based antibiotics.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBTM-P1 is an antimicrobial peptide that primarily targets bacterial membranes, demonstrating potent antibacterial activity against both Gram-positive and Gram-negative bacteria. Its mechanism involves the formation of ion-permeable channels in the inner mitochondrial membrane, leading to disruptions in mitochondrial energy processes. BTM-P1 is suitable for research applications focused on understanding antimicrobial mechanisms and investigating the potential therapeutic use of peptide-based antibiotics.
Product Information
Catalog NumA49033
FormulaC134H219N33O31
Molecular Weight2788.38
CAS Number845623-61-2
SequenceVal-Ala-Pro-Ile-Ala-Lys-Tyr-Leu-Ala-Thr-Ala-Leu-Ala-Lys-Trp-Ala-Leu-Lys-Gln-Gly-Phe-Ala-Lys-Leu-Lys-Ser
Sequence shorteningVAPIAKYLATALAKWALKQGFAKLKS
SMILESO=C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(NCC(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N
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