TP4, an antimicrobial peptide derived from Nile tilapia, primarily targets bacterial membranes. It demonstrates significant inhibitory effects against a range of gram-positive and gram-negative bacteria, with minimum inhibitory concentrations (MIC) ranging from 0.03 to 10 μg/mL. Additionally, TP4 enhances immune responses and promotes intestinal health, while exhibiting antioxidant properties. Its potential anti-tumor effects are attributed to the induction of necrosis via mitochondrial dysfunction in cancer cells, making TP4 a valuable candidate for various biomedical research applications.
TP4, an antimicrobial peptide derived from Nile tilapia, primarily targets bacterial membranes. It demonstrates significant inhibitory effects against a range of gram-positive and gram-negative bacteria, with minimum inhibitory concentrations (MIC) ranging from 0.03 to 10 μg/mL. Additionally, TP4 enhances immune responses and promotes intestinal health, while exhibiting antioxidant properties. Its potential anti-tumor effects are attributed to the induction of necrosis via mitochondrial dysfunction in cancer cells, making TP4 a valuable candidate for various biomedical research applications.
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