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XT-4

Catalog No.: A49056
Antimicrobial Peptide
XT-4 is an antimicrobial peptide derived from the skin secretions of Xenopus tropicalis, targeting bacterial membranes. It exhibits significant antimicrobial activity against Escherichia coli, with a minimum inhibitory concentration (MIC) of 18 μM. XT-4 is suitable for research applications focusing on antimicrobial mechanisms and the development of novel therapeutic agents against bacterial infections.
XT-4 398143-81-2 Antimicrobial Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionXT-4 is an antimicrobial peptide derived from the skin secretions of Xenopus tropicalis, targeting bacterial membranes. It exhibits significant antimicrobial activity against Escherichia coli, with a minimum inhibitory concentration (MIC) of 18 μM. XT-4 is suitable for research applications focusing on antimicrobial mechanisms and the development of novel therapeutic agents against bacterial infections.
Product Information
Catalog NumA49056
FormulaC107H176N28O27S
Molecular Weight2318.78
CAS Number398143-81-2
SequenceGly-Val-Phe-Leu-Asp-Ala-Leu-Lys-Lys-Phe-Ala-Lys-Gly-Gly-Met-Asn-Ala-Val-Leu-Asn-Pro-Lys
Sequence shorteningGVFLDALKKFAKGGMNAVLNPK
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC(CN)=O)C(C)C)=O)=O)CC(C)C)=O)CC(O)=O)=O)C)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)=O)C)=O)CCCCN)=O)=O)=O)CCSC)=O)CC(N)=O)=O)C)=O)[C@@H](C)C)=O)CC(C)C)=O)CC(N)=O)(=O)N3[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CCC3
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