p38-MAPK



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Catalog No. Product Name Application Product Information
A16015

AL 8697

p38 MAPK inhibitor
AL-8697 is a selective p38 MAPK(mitogen-activated protein Kinase) inhibitor, which is also named P38α inhibitor. It has the function of inhibiting the activity of P38 MAPK.
A10970

AMG 548

p38 MAPK inhibitor
AMG 548 is a potent and selective inhibitor of p38α. It displays >1000-fold selectivity against 36 other kinases, and it inhibits whole blood LPS-stimulated TNFα.
A10092

Asiatic acid

Anti-inflammatory agent

Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties. Asiatic acid derivative synthesis can be used as Anticancer agents; Glycogen phosphorylase inhibitors; Hepatoprotectants.

A12021

Asiaticoside

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Asiaticoside (Madecassol) is the active chemical component of the plant Centella asiatica. Asiaticoside is used to study potential treatments for wounds and burns.
A13563

BMS-582949

p38 MAPK inhibitor
BMS-582949 Is a Dual Action p38 Kinase Inhibitor Well Suited To Avoid Resistance Mechanisms That Increase p38 Activation in Cells.
A16058

DBM 1285 dihydrochloride

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DBM 1285 dihydrochloride is a p38 MAPK inhibitor. Supresses p38 phosphorylation and LPS-induced TNF-?? production in macrophages and in vivo.
A13553

Dilmapimod

p38 MAPK inhibitor
Dilmapimod is p38 MAPK inhibitor.
A10148

Doramapimod (BIRB-796)

p38 MAPK inhibitor
Doramapimod (BIRB 796) is a small molecule inhibitor of p38 MAPK,which plays a critical role in regulating the production of proinflammatory cytokines.
A16037

EO 1428

P38 MAPK inhibitor
EO 1428 is a synthetic 4-aminobenzophenone small molecule identified in an optimization study for inhibitors of p38 MAP kinase.
A16038

JX 401

P38 MAPK inhibitor
JX 401 is a potent, reversible inhibitor of the p38α isoform of MAP kinase (IC50 = 32 nM).
A10545

LY2228820

p38 MAPK inhibitor
LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity.
A12408

ML-3043

p38 MAPK inhibitor
ML-3043 is a p38 MAPK inhibitor (IC50 = 0.38 μM). Inhibits the release of IL-1β and TNF-α in a peripheral blood mononuclear cell (PBMC) assay (IC50 values are 0.039 and 0.16 μM respectively).
A13551

Pamapimod (R-1503)

p38 MAPK inhibitor
Pamapimod is a novel p38 mitogen-activated protein kinase inhibitor.
A11221

PD 169316

p38 MAPK inhibitor
PD 169316 (PD169316) is a selective inhibitor of p38 MAPK.1 that inhibits p38 MAPK with an IC50 of 89 nM.
A10895

Pexmetinib (ARRY-614)

p38 MAPK inhibitor
Pexmetinib is a potent inhibitor of cytokine synthesis, via the dual inhibition of p38 mitogen-activated protein kinase (MAPK), and Tie2/Tek receptor tyrosine kinase.
A11078

PH-797804

p38 MAPK inhibitor
PH-797804 is a diarylpyridinone inhibitor of p38 mitogen-activated protein (MAP) kinase.
A13552

RWJ-67657

p38 MAPK inhibitor
RWJ-67657 is a potent p38 MAPK inhibitor.
A10823

SB 202190

p38 MAPK Inhibitor
SB202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinase.
A10824

SB 203580

p38 MAPK inhibitor
SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27.
A11562

SB 239063

p38 MAPK inhibitor
SB 239063 is a potent and selective p38 MAP kinase inhibitor (IC50 = 44 nM for p38α). SB 239063 displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580. SB 239063 reduces inflammatory cytokine production and is neuroprotective following oral administration in vivo.
A16055

SB 706504

p38 MAPK inhibitor
SB 706504 is a p38 MAPK inhibitor, preventing LPS-induced transcription of a range of chemokineis and cytokines in chronic obstructive pulmonary disease monocyte derived macrophages.
A13678

SB-242235

p38 MAPK inhibitor
SB-242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases such as autoimmune or inflammatory diseases.
A11563

SD-06

p38 MAPK inhibitor
SD-06 is a p38 MAP kinase inhibitor; inhibits p38?? with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po).
A11321

Skepinone-L

p38 MAPK inhibitor
Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor.
A11101

SKF 86002 Dihydrochloride

p38 MAPK inhibitor
SKF 86002 Dihydrochloride is inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 uM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 uM).

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