SB 203580

Catalog No.: A10824

p38 MAPK inhibitor

SB 203580

SB 203580 Chemical Structure

CAS NO. 152121-47-6

SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27.

Availability: In stock

Package Price Qty
25 mg

Regular Price: $50.00

Special Price $45.00

50 mg

Regular Price: $80.00

Special Price $72.00

100 mg

Regular Price: $120.00

Special Price $108.00

200 mg

Regular Price: $230.00

Special Price $207.00

10mM * 1mL in DMSO

Regular Price: $67.00

Special Price $60.30

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SB 203580 is a specific inhibitor of p38α and p38β which suppresses downstream activation of MAPKAP kinase-2 and heat shock protein 27.
Targets
p38 MAPK (THP-1 cells) PKB (THP-1 cells)
0.3 μM-0.5 μM3 μM-5 μM
In vitro DMSO 43 mg/mL (113.92 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.5 mL 132.49 mL 264.97 mL
0.5 mM 5.3 mL 26.5 mL 52.99 mL
1 mM 2.65 mL 13.25 mL 26.5 mL
5 mM 0.53 mL 2.65 mL 5.3 mL

*The above data is based on the productmolecular weight 377.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10824
Actions Inhibitor
M. Wt 377.4
Formula C21H16FN3OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 152121-47-6
Synonyms SB-203580, SB203580
SMILES CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F

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