Biological Activity
BMS-582949 hydrochloride is an orally active and highly selective p38α MAPK inhibitor, with an IC50 of 13 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.58 mL | 112.88 mL | 225.76 mL |
0.5 mM | 4.52 mL | 22.58 mL | 45.15 mL |
1 mM | 2.26 mL | 11.29 mL | 22.58 mL |
5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
*The above data is based on the productmolecular weight 442.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21914 |
---|---|
Actions | Inhibitor |
CAS No. | 912806-16-7 |
Formula | C22H27ClN6O2 |
M. Wt | 442.94 |
Purity | >98% |
Synonyms | BMS 582949, BMS582949 |
SMILES | O=C(NCCC)C1=CN(N=CN=C2NC3=CC(C(NC4CC4)=O)=CC=C3C)C2=C1C.[H]Cl |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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