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SB202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinase.
Targets
| p38α (Cell-free assay) | p38β (Cell-free assay) | |||
| 50 nM | 100 nM |
| In vitro (25°C) | DMSO | 66 mg/mL (199.19 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 12 mg/mL (36.21 mM) | ||
| In vivo | 1% DMSO/30% polyethylene glycol/1% Tween 80 | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.18 mL | 150.92 mL | 301.84 mL |
| 0.5 mM | 6.04 mL | 30.18 mL | 60.37 mL |
| 1 mM | 3.02 mL | 15.09 mL | 30.18 mL |
| 5 mM | 0.6 mL | 3.02 mL | 6.04 mL |
*The above data is based on the productmolecular weight 331.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A10823 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 331.3 |
| Formula | C20H14N3OF |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 152121-30-7 |
| Synonyms | SB-202190, SB202190 |
| SMILES | C1=CC(=O)C=CC1=C2NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F |
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