Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order

SB 202190

Catalog No.: A10823

p38 MAPK Inhibitor

SB 202190

SB 202190 Chemical Structure

CAS NO. 152121-30-7

SB202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinase.

Availability: In stock

Package Price Qty
10 mg
50 mg
100 mg
200 mg
10mM * 1mL in DMSO
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Dan Zhao, .et al. From crypts to enteroids: establishment and characterization of avian intestinal organoids, Poult Sci, 2022, Mar; 101(3): 101642 PMID: 35016046
  • Yang PM, .et al. p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma, Am J Cancer Res, 2019, Oct 1;9(10):2120-2139 PMID: 31720078
  • Tsai CC, .et al. Protease-activated receptor 2 induces migration and promotes Slug-mediated epithelial-mesenchymal transition in lung adenocarcinoma cells, Biochim Biophys Acta Mol Cell Res, 2018, Oct 13. pii: S0167-4889(18)30452-X PMID: 30321617
  • Jia-Shiuan Tsai, .et al. Cadmium Activates Multiple Signaling Pathways That Coordinately Stimulate Akt Activity to Enhance c-Myc mRNA Stability, PLoS One, 2016, 11(1): e0147011 PMID: 26751215

Biological Activity

SB202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinase.
p38α (Cell-free assay) p38β (Cell-free assay)
50 nM100 nM
In vitro (25°C) DMSO 62 mg/mL (187.12 mM)
Water Insoluble
Ethanol 11 mg/mL (33.19 mM)
In vivo 5%DMSO+40%PEG300+5%Tween80+50%H2O 7 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.18 mL 150.92 mL 301.84 mL
0.5 mM 6.04 mL 30.18 mL 60.37 mL
1 mM 3.02 mL 15.09 mL 30.18 mL
5 mM 0.6 mL 3.02 mL 6.04 mL

*The above data is based on the productmolecular weight 331.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10823
Actions Inhibitor
CAS No. 152121-30-7
Formula C20H14N3OF
M. Wt 331.3
Purity >98%
Synonyms SB-202190, SB202190

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy SB 202190 | SB 202190 Supplier | purchase | cost | manufacturer | order | distributor | buy 152121-30-7| 152121-30-7 Supplier | purchase 152121-30-7 | 152121-30-7 cost | 152121-30-7 manufacturer | order 152121-30-7 | 152121-30-7 distributor