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Biological Activity
MW-150 dihydrochloride dihydrate (MW01-18-150SRM dihydrochloride dihydrate) is a selective, CNS penetrant, and orally active inhibitor of p38α MAPK with a Ki of 101 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.39 mL | 101.95 mL | 203.9 mL |
| 0.5 mM | 4.08 mL | 20.39 mL | 40.78 mL |
| 1 mM | 2.04 mL | 10.2 mL | 20.39 mL |
| 5 mM | 0.41 mL | 2.04 mL | 4.08 mL |
*The above data is based on the productmolecular weight 490.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21860 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1661020-92-3 |
| Formula | C24H29Cl2N5O2 |
| M. Wt | 490.43 |
| Purity | >98% |
| Synonyms | MW01-18-150SRM dihydrochloride dihydrate, MW150, MW 150 |
| SMILES | CN1CCN(C2=NN=C(C3=CC=C4C=CC=CC4=C3)C(C5=CC=NC=C5)=C2)CC1.Cl.O.Cl.O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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