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p38 MAPK inhibitor

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Catalog No. A11582

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
TAK-715 10mg A11582-10

Regular Price: $110.00

Special Price: $99.00

TAK-715 25mg A11582-25

Regular Price: $220.00

Special Price: $198.00

TAK-715 50mg A11582-50

Regular Price: $320.00

Special Price: $288.00

TAK-715 100mg A11582-100

Regular Price: $550.00

Special Price: $495.00

TAK-715 10mM * 1mL in DMSO A11582-10mM-D

Regular Price: $80.00

Special Price: $72.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

TAK 715 an inhibitor of p38 MAPK (IC50 = 7.1 nM for p38 MAPKα), Wnt/beta-catenin signaling, and Inhibits 22 kinases by more than 80%, including CK 1δ/ε.


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Chemical Information

Catalog Num A11582
Actions Inhibitor
M. Wt 399.51
Formula C24H21N3OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 303162-79-0
Synonyms TAK715, TAK 715

Biological Activity

TAK 715 an inhibitor of p38 MAPK (IC50 = 7.1 nM for p38 MAPKα), Wnt/beta-catenin signaling, and Inhibits 22 kinases by more than 80%, including CK 1δ/ε.
Target Value
p38αIC50: 7.1nM
p38βIC50: 0.20μM
p38γIC50: >10μM
p38δIC50: >10μM
JNK1IC50: >10μM
ERK1IC50: >10μM
IKKβIC50: >10μM
MEKK1IC50: >10μM
TAK1IC50: >10μM


Solubility (25°C) * In vitro DMSO 80 mg/mL (200.24 mM)
Water <1 mg/mL (<1 mM)
Ethanol 16 mg/mL (40.04 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.03 mL 125.15 mL 250.31mL
0.5 mM 5.01 mL 25.03 mL 50.06 mL
1 mM 2.5 mL 12.52 mL 25.03 mL
5 mM 0.5 mL 2.5 mL 5.01 mL

*The above data is based on the productmolecular weight 399.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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