Catalog No.
Product Name
Application
Product Information
Citations
-
Antibacterial Agent
Cerastecin D is an antibacterial agent with activity against Acinetobacter baumannii ATCC19606, exhibiting an MITC95 value of 165 nM. This compound is valuable in research focused on bacterial resistance and development of new antimicrobial therapies. Its potential for targeting multi-drug resistant pathogens makes it significant in the field of infectious disease research. -
Antibiotic
Respinomycin A1 is a natural antibiotic derived from Streptomyces sp. RK-483, exhibiting antimicrobial activity against various bacterial strains. This compound has been shown to induce differentiation in leukemic K-562 cells, highlighting its potential utility in cancer research and therapeutic development. Its unique mechanism of action makes Respinomycin A1 a valuable tool for investigating cellular differentiation and the pathways involved in leukemia. -
Bacterial Inhibitor
Cellocidin is a bacterial inhibitor that targets the α-ketoglutarate-succinate system in Xanthomonas species. This agricultural antibiotic demonstrates preventive activity against rice bacterial leaf blight, offering a valuable tool for managing bacterial infections in crop production. Its mechanism of action makes it an essential reagent for research into plant-pathogen interactions and the development of sustainable agricultural practices. -
Bacterial Inhibitor
Phentolamine acetate is a bacterial inhibitor that targets and disrupts the growth of specific bacterial strains, including Staphylococcus aureus. This compound exhibits notable anti-inflammatory and anticancer properties, highlighting its potential for diverse biological applications. Its significant in vitro activity makes it a valuable tool for researchers studying bacterial infections and inflammation-related disorders. -
Antibacterial Agent
Sulfamethomidine is a sulfonamide antibiotic that primarily targets bacterial folic acid synthesis by inhibiting dihydropteroate synthase. This compound exhibits potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria. It is commonly utilized in research applications focusing on antimicrobial efficacy, resistance mechanisms, and the development of combination therapies. -
Antibacterial Agent
7-Phloroeckol is a potent antibacterial agent targeting virulence-associated proteins of Pseudomonas aeruginosa. It demonstrates strong and stable binding to 18 distinct proteins, highlighting its potential in combating bacterial infections. This compound is valuable for research focused on understanding and treating Pseudomonas aeruginosa infections. -
Antibacterial agent
Antibacterial agent 160 is a potent antibacterial compound that disrupts bacterial DNA function, leading to cell death. This reagent effectively eliminates bacterial cells and inhibits biofilm formation, making it a valuable tool for studies on bacterial infections and resistance mechanisms. Its application extends to researching antibacterial efficacy and strategies for combating biofilm-associated infections. -
Beta-lactamase Inhibitor
Xeruborbactam is a potent boronic acid beta-lactamase inhibitor that targets both serine and metallo beta-lactamases with high efficacy. Demonstrating activity in the nanomolar range, it serves as an ultra-broad-spectrum agent in combating antibiotic resistance. Xeruborbactam is valuable for research applications focused on understanding beta-lactamase activity and developing novel antimicrobial strategies. -
Antibacterial Agent
Javanicin is an antibacterial agent that targets various pathogenic bacteria, demonstrating activity against Bacillus megaterium, Staphylococcus aureus, Salmonella typhi, and Escherichia coli. Additionally, Javanicin exhibits weak cytotoxicity against the human lung cancer cell line, making it a potential candidate for research into antibacterial and anticancer applications. -
Antibacterial Agent
Antibacterial agent 156 is a potent bactericidal compound that selectively targets cell-wall synthesis in Clostridium difficile. This agent demonstrates significant antibacterial activity, with a minimal inhibitory concentration (MIC) of 0.5 μg/mL against a broad range of strains (MIMIC50 of 101 strains) and an MIC90 of 1 μg/mL. It is an important tool for research applications focused on combating C. difficile infections and studying bacterial cell-wall biosynthesis. -
Antibacterial Agent
Antibacterial Agent 255 is a selective inhibitor of 4-diphosphocytidyl-2-C-methyl-D-erythritol (IspE), demonstrating potent antibacterial activity with IC50 values of 13.0 µM for E. coli IspE, 8.0 µM for K. pneumoniae IspE, and 20 µM for A. baumannii IspE. This compound is instrumental in the study of bacterial biosynthesis pathways and can be utilized in antibacterial drug development research. -
Bacterial Inhibitor
Ethionamide hydrochloride is an antituberculosis agent that acts as a bacterial inhibitor. It disrupts mycobacterial cell wall synthesis by inhibiting fatty acid synthesis, leading to potential bacteriostatic or bactericidal effects based on concentration and microorganism susceptibility. Ethionamide hydrochloride forms an adduct with NAD+, which is crucial for its antimicrobial activity. This compound is primarily utilized in research for understanding tuberculosis treatment and the mechanisms of drug resistance in Mycobacterium tuberculosis. -
Antibacterial Agent
5-Hydroxymethyl flucloxacillin is an active metabolite of Flucloxacillin, targeting bacterial infections. This compound demonstrates notable antibacterial activity, making it useful for research applications focused on antimicrobial resistance and bacterial pathogenesis studies. Its efficacy in inhibiting bacterial growth supports investigations into therapeutic strategies for treating infections caused by resistant strains. -
Antibiotic
Andrimid is a lipoacyl peptide that functions as an antibiotic through its action on bacterial cell envelope synthesis. It demonstrates significant antimicrobial activity, making it a valuable compound for researching antibiotic mechanisms and resistance. Additionally, Andrimid has potential applications in both biomedical research and agricultural biotechnology, particularly in developing strategies for disease control. -
Anti-Bacterial Agent
Saquayamycin C is an anti-bacterial agent with significant antimicrobial activity, though it exhibits a weaker efficacy against Gram-negative bacteria. This compound also demonstrates cytotoxic effects against leukemia P388 cells, including those resistant to Adriamycin. Its applications extend to research in cancer biology and microbial resistance, making it valuable for studies focused on therapeutic development and resistance mechanisms. -
HIV-I Integrase Inhibitor
Bis-T-23 is a potent inhibitor of HIV-1 integrase, acting through a tyrphostin derivative mechanism. This compound has been shown to promote actin-dependent dynamin oligomerization, highlighting its role in cellular processes related to viral replication. Bis-T-23 is valuable for research focused on HIV and chronic kidney diseases (CKD), providing insights into the intersection of viral infection and renal pathophysiology. -
Myosin I Inhibitor
ZJS178 is a selective inhibitor of myosin I, exhibiting significant antifungal activity against Fusarium graminearum. This compound effectively reduces the synthesis of the mycotoxin deoxynivalenol (DON) and is valuable for research on plant diseases, particularly wheat scab. ZJS178 serves as a potent tool for studies aimed at understanding myosin I functions in fungal pathogenesis and developing strategies for disease management in crops. -
Mitotic kinesin Inhibitor
Mitotic kinesin-IN-1 hydrochloride is a potent inhibitor of mitotic kinesin, specifically designed to disrupt the process of mitosis. This compound effectively impairs cell proliferation and has applications in cancer research, as well as investigations into cardiac hypertrophy, immune and inflammatory disorders, and fungal infections. Its ability to hinder mitotic activity makes it a valuable tool for studying various cellular processes and pathways related to these conditions. -
Anti-HSV Agent
Arabinosylhypoxanthine is a purine nucleoside analog that selectively inhibits viral DNA synthesis. It demonstrates significant anti-herpes simplex virus (HSV) activity, making it a valuable tool for research on herpes simplex virus infections. This compound can be utilized to investigate mechanisms of antiviral action and to develop therapeutic strategies against HSV. -
HBV Inhibitor, EBV Inhibitor
FMAU is a nucleoside analog that primarily inhibits the replication of hepatitis B virus (HBV) and Epstein-Barr virus (EBV). Once phosphorylated by human thymidine kinase, FMAU is incorporated into DNA, serving as a valuable marker for cell proliferation. Its research applications extend to studies on herpes simplex virus infection and various cancer types. -
Fungicidal Agent
N,N-Bis(3-aminopropyl)dodecylamine serves as a potent fungicidal agent targeting Aspergillus niger. It exerts its antifungal activity by inducing oxidative stress and modulating the activity of various antioxidant and mitochondrial enzymes in a concentration- and time-dependent manner. Additionally, this compound disrupts fungal organelles and alters mitochondrial morphology, leading to impaired mitochondrial functions. N,N-Bis(3-aminopropyl)dodecylamine is valuable for research into fungicidal mechanisms and the role of oxidative stress in Aspergillus niger. -
Antibacterial Agent
Octyl decyldimethyl ammonium chloride is a quaternary ammonium compound functioning as an antibacterial agent. This reagent disrupts microbial cell membranes, resulting in cytotoxic effects. Additionally, it has been observed to increase the secretion of pro-inflammatory cytokine IL-1α, indicating potential immunological implications. Its application may be relevant in studying antibacterial mechanisms and evaluating skin irritation effects in research settings. -
NF-κB Inhibitor, GPx Inhibitor, HIV Replication Inhibitor
α-MSH (11-13) acetate is a selective melanocortin-1 receptor ligand that functions as an inhibitor of NF-κB, GPx activity, and HIV replication. It induces an acute elevation of intracellular calcium levels under certain costimulation or pathway inhibition conditions. This compound effectively suppresses TNF-α-induced NF-κB activation, inhibits colony formation of Staphylococcus aureus and Candida albicans, and demonstrates potential in the study of infections related to these pathogens, as well as in traumatic brain injury, corneal epithelial wounds, and inflammatory bowel disease research. -
Melanin Biosynthesis Inhibitor
Scytalol A is a selective inhibitor of dihydroxynaphthalene melanin biosynthesis in Lachnellula sp. A32-89, effectively disrupting melanin production without affecting the growth of the organism. This compound is valuable for research investigating melanin biosynthesis pathways and can be utilized in studies focused on fungal pigmentation and its applications in various biotechnological fields. -
Griseofulvin Metabolite
6-O-Demethyl griseofulvin is a significant metabolite of Griseofulvin, primarily acting on fungal cell division by inhibiting microtubule formation. This compound demonstrates antifungal activity, making it valuable in studying the efficacy of antifungal treatments and the metabolic pathways involving Griseofulvin. Its applications extend to research focused on dermatophyte infections and fungal resistance mechanisms. -
Metabolite
BTS44596 (Prochloraz-desimidazole-formylamino) is a key metabolite of the antifungal agent Prochloraz, primarily targeting regulatory monitoring applications. This compound serves as a critical target analyte for assessing Prochloraz residue limits in fruits and vegetables. Additionally, it facilitates simultaneous detection using LC-MS/MS methodology, making it an essential tool for food safety and environmental studies. -
midazopyridine amide compound
Q203 (IAP6) is a midazopyridine amide compound. Q203 is active against Mycobacterium tuberculosis H37Rv with an MIC50 of 2.7 nM in culture broth medium. - Clavulanic acid is a mechanism-based β-lactamase inhibitorcombined with penicillin group antibiotics to overcome certain types of antibiotic resistance.
-
NNRT inhibitor
MK-1439 is a non-nucleoside reverse transcriptase inhibitor - Moxidectin is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms.
-
non-ionic emulsifying agent
Polyoxyethylene stearate (POES) is a non-ionic emulsifying agent. -
DprE1 inhibitor
DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has antituberculosis effect. -
squalene synthetase inhibitor
YM-53601 free base is a squalene synthetase inhibitor which suppresses lipogenic biosynthesis and lipid secretion in rodents. - PNU-176798 is an antimicrobial agent, targeting protein synthesis in a wide spectrum of gram-positive and anaerobic bacteria.
-
HIV protease inhibitor
Fosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease. -
HIV reverse transcriptase inhibitor
Dapivirine is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) - D-(+)-Phenyllactic acid is an anti-bacterial agent, excreted by Geotrichum candidum, inhibits a range of Gram-positive from humans and foodstuffs and Gram-negative bacteria found in humans.
- KW-8232 free base is an anti-osteoporotic agent, and can reduces the biosynthesis of PGE2.
-
NNRT inhibitor
Lersivirine (UK-453,061) is a next-generation nonnucleoside reverse transcriptase inhibitor, active against wild-type HIV-1 and several nonnucleoside reverse transcriptase inhibitor-resistant strains. -
natural cyclic oligopeptide antibiotic
Antibiotic that inhibits bacterial protein synthesis. Inhibits mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery and the activity of initiation factor 2 (IF-2). Antitumor agent; induces cell cycle arrest and apoptosis in breast cancer cells via downregulation of FOXM1 expression. -
enteroviral capsid binder (CB)
Vapendavir (BTA798) is a potent enteroviral capsid binder (CB). - Ozenoxacin is an experimental quinolone antibiotic being developed for the treatment of impetigo and other dermatological bacterial infections.
-
Neuraminidase inhibitor
Laninamivir is a neuraminidase inhibitor which is being researched for the treatment and prophylaxis of Influenzavirus A and Influenzavirus B. - Sulfaclozine (Sulfachloropyrazine) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).
