Catalog No.
Product Name
Application
Product Information
Citations
-
Anti-Bacterial Agent
Neoviridogrisein III is an anti-bacterial agent primarily effective against Gram-positive bacteria and mycoplasma. Its mechanism of action involves disrupting bacterial cell function, making it a valuable tool in microbiological research. Neoviridogrisein III is suitable for studies focused on bacterial resistance and the development of new antimicrobial strategies. -
Anti-Bacterial Agent
Baciphelacin is an anti-bacterial agent primarily effective against gram-positive bacteria. It exhibits significant inhibitory activity against Newcastle disease virus and leukemia P-388 cells, making it a valuable tool for research in microbiology and cancer studies. This compound is suitable for investigating bacterial resistance mechanisms and evaluating antiviral and antitumor effects in various experimental models. -
Antibacterial agent
Metallo-β-lactamase-IN-12 is a dual inhibitor targeting both metallo-β-lactamases (MβLs) such as NDM-1 and IMP-1, and serine β-lactamases (SβLs) including OXA-48 and KPC-2. It demonstrates potent antibacterial activity, with IC50 values of 0.64 μM, 1.32 μM, 1.01 μM, and 0.57 μM against these resistant enzymes. This compound is valuable for research applications focused on combating antibiotic resistance and understanding β-lactamase mechanisms. -
Antibacterial
2-Keto-L-gulonic acid is a key precursor in the biosynthesis of vitamin C and exhibits antibacterial activity. It effectively inhibits the growth of Bacillus pumilus and Ketogulonicigenium vulgare, making it valuable in microbiological studies. This compound is useful in research applications focused on antimicrobial agents and vitamin C production processes. -
Anti-Bacterial Agent
Epicillin is a semisynthetic broad-spectrum penicillin that acts as an antibacterial agent by inhibiting the synthesis of bacterial cell walls. It is effective against a variety of Gram-positive and some Gram-negative bacteria, showcasing its potential in treating bacterial infections. Researchers can employ Epicillin in studies focused on antibiotic resistance, mechanisms of bacterial virulence, and the development of new antibacterial therapies. -
Bacterial Inhibitor
Ianthelliformisamine A TFA is a bacterial inhibitor that enhances antibiotic efficacy against resistant Gram-negative bacteria. It demonstrates potent bactericidal activity against Staphylococcus aureus, with an IC50 value of 3.8 μM and a minimum inhibitory concentration of 25 μM. The biological activity is attributed to the structural variations of its synthetic derivatives and their interaction with various amino ester derivatives, making it a valuable tool for research in antibiotic resistance and bacterial infections. -
Anti-Bacterial Agent
Glysperin B is an anti-bacterial agent primarily targeting both Gram-positive and Gram-negative bacteria, including strains resistant to aminoglycoside antibiotics. Its mechanism of action involves disrupting bacterial growth and viability, making it a valuable compound for research in infectious disease studies and antimicrobial resistance. Glysperin B is suitable for applications involving the evaluation of new therapeutic approaches against resistant bacterial pathogens. -
Bacterial
Tetromycin A is a tetronic acid-based antibiotic targeting bacterial pathogens. It exhibits significant antibacterial activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus. Additionally, related tetromycin derivatives have demonstrated anti-trypanosomal properties and inhibit the cysteine protease cathepsin L, with inhibition constants (Ki) in the low micromolar range, making them valuable tools for research into both bacterial and parasitic infections. -
Anti-Bacterial Agent
Olivomycin D is an anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits potent antimicrobial activity, making it valuable in research focused on bacterial infections and antibiotic resistance. Its limited efficacy against Gram-negative bacteria provides insights into the mechanisms of bacterial susceptibility and resistance. -
Antifungal Agent
Antibacterial agent 230 is an antifungal agent targeting fluconazole-resistant fungi. It exhibits a minimal inhibitory concentration (MIC) ranging from 2.0 to 16.0 μg/mL, demonstrating significant efficacy against resistant strains. This compound is suitable for research applications focused on fungal resistance mechanisms and the development of new antifungal therapies. -
Anti-Bacterial Agent
Olivomycin B is an anti-bacterial agent that exhibits strong activity against Gram-positive bacteria while demonstrating weaker efficacy against Gram-negative bacteria. This compound is significant in research applications focused on bacterial infections and the development of novel antibiotics. Its selective action makes it a valuable tool for studying mechanisms of bacterial resistance and exploring new therapeutic strategies. -
Antibacterial Agent
Tembetarine chloride is an alkaloid derived from Tinospora cordifolia, primarily acting as an antibacterial agent. It demonstrates significant antibacterial activity while exhibiting weak cytotoxicity against mouse fibroblasts (L929) and human embryonic kidney cells (HEK293), with IC50 values of 1245.33 μg/mL and 1642.81 μg/mL, respectively. This compound is suitable for research applications focused on understanding antibacterial mechanisms and evaluating cytotoxic effects in cellular models. -
Anti-Bacterial Agent
Grahamimycin B is an anti-bacterial agent with demonstrated weak activity against Gram-positive bacteria, as well as varying effects on Gram-negative bacteria, cyanobacteria, and green algae. Its unique biochemical properties make it a valuable compound for research in microbial inhibition and the study of bacterial resistance mechanisms. Grahamimycin B serves as a useful tool in investigations related to antibiotic development and the ecological impact of microbial communities. -
Anti-Bacterial Agent
Neoviridogrisein II is an anti-bacterial agent that exhibits activity against Gram-positive bacteria and mycoplasma. Its mechanism involves disrupting cellular processes in target organisms, making it a valuable compound for research applications focused on the development of novel antibacterial therapies and the study of bacterial resistance mechanisms. Neoviridogrisein II is ideal for investigations seeking to understand bacterial pathogenesis and the efficacy of antimicrobial treatments. -
Anti-Bacterial Agent
Cirramycin B1 is an anti-bacterial agent effective against Gram-positive and Gram-negative bacteria, as well as mycoplasmas. This compound demonstrates strong antimicrobial activity, making it a valuable reagent for research focused on combating bacterial infections and studying antibiotic resistance mechanisms. Its broad spectrum of activity supports investigations in microbiology and pharmacology. -
Anti-bacterial Agent
Diaporthin is a phytotoxin derived from Cryphonectria parasitica, exhibiting potent antibacterial properties. This compound is effective against various bacterial strains, making it a valuable tool for studies focused on antimicrobial activity and resistance. Its unique mechanism of action positions Diaporthin as a significant candidate for research in the development of new antibacterial agents. -
Anti-Bacterial Agent
Megovalicin D is an anti-bacterial agent known for its efficacy against Bacillus subtilis and Escherichia coli, as well as its inhibitory action on Pseudomonas aeruginosa. This compound is critical for research applications focused on combating bacterial infections and studying the mechanisms of bacterial resistance. Its broad-spectrum activity makes it a valuable tool in microbiological research and antibiotic development. -
Bacterial Inhibitor
Lysine hydroxamate is an amino acid hydroxamate that acts as a bacterial inhibitor by selectively reducing the growth of Escherichia coli K-12. This compound demonstrates significant antibacterial activity among amino acid hydroxamates, with a unique mechanism of action that allows for the reversible inhibition of bacterial growth through the addition of L-serine. Lysine hydroxamate provides a valuable tool for researchers investigating bacterial growth inhibition and exploring amino acid analogs in microbial studies. -
Antifbacterial Agent
Antibacterial Agent 323 is characterized as an antibacterial compound with modest activity against bacterial pathogens. It has potential applications in the study of bacterial infections, specifically targeting strains of Acinetobacter baumannii. Researchers can utilize this reagent to explore mechanisms of resistance and evaluate therapeutic strategies for combating bacterial diseases. -
Antibacterial Agent
2-Quinoxalinecarboxylic acid is an antibacterial agent specifically targeting Mycobacterium tuberculosis with a minimum inhibitory concentration (MIC) greater than 128 µg/mL. This compound shows potential in the study of tuberculosis, contributing to the development of new therapeutic strategies against this persistent pathogen. -
Anti-Bacterial Agent
Granaticin A functions as an anti-bacterial agent by inhibiting the initial stages of RNA biosynthesis. It exhibits activity against Gram-positive bacteria and demonstrates weak inhibitory effects on Mycobacterium and Vaginal trichomonas. Additionally, Granaticin A has potential applications in cancer research due to its ability to inhibit tumor cell proliferation. -
Anti-Bacterial Agent
Empedopeptin is an anti-bacterial agent targeting Gram-negative bacteria. It exhibits significant activity against a range of these pathogens, making it a valuable reagent for research in microbiology and infectious disease studies. Its mechanism of action and efficacy position it as a promising candidate for further exploration in the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Citreamicin β is an anti-bacterial agent that exhibits potent activity against Gram-positive aerobic and anaerobic bacteria. This compound is particularly useful in microbiological research for investigating bacterial resistance mechanisms and the efficacy of antibacterial therapies. Its targeted action provides valuable insights into the development of new antibacterial strategies. -
Antibacterial Agent
Antibacterial Agent 303 is an antibacterial compound that demonstrates significant efficacy against multidrug-resistant strains, particularly with minimum inhibitory concentrations (MICs) of 10 and 100 µg/mL against Pseudomonas aeruginosa MDR1 and Staphylococcus aureus MDR strains, respectively. This agent exhibits strong binding affinities for E. coli DNA gyrase and Candida albicans lanosterol 14α-demethylase. Antibacterial Agent 303 is suitable for research focused on drug-resistant infections, providing valuable insights into combating antimicrobial resistance. -
Antibacterial Agents
CAP 3 is a cholic acid-peptide conjugate that acts as an effective antibacterial agent targeting Gram-negative bacteria. It demonstrates potent antibacterial activity with minimum inhibitory concentration (MIC99) values of 8 μM, 16 μM, and 16 μM against E. coli, Klebsiella pneumoniae, and Acinetobacter baumannii, respectively. CAP 3 functions by disrupting the structural integrity of bacterial lipopolysaccharide (LPS) outer membranes, leading to rapid bacterial cell death. Additionally, it inhibits biofilm formation and shows efficacy against drug-resistant strains, making it valuable for addressing persistent bacterial infections in research settings. -
Anti-Bacterial Agent
Kerriamycin A is a potent anti-bacterial agent targeting Gram-positive bacteria. This compound exhibits significant antibacterial activity and has also been shown to inhibit ascites cancer in animal models, making it valuable for further research in infectious diseases and cancer therapy. Its dual mechanism offers promising avenues for studies in therapeutic applications. -
Anti-Bacterial Agent
Megovalicin H is a potent antibacterial agent that targets a broad spectrum of bacteria, including Bacillus subtilis and Escherichia coli, as well as Pseudomonas aeruginosa. Its efficacy in inhibiting bacterial growth makes it a valuable reagent for microbiological studies and research into antibiotic resistance mechanisms. Megovalicin H is suitable for applications in both basic and applied microbiology. -
Antibiotic
Istamycin Y0 is an aminoglycoside antibiotic with primary activity against bacterial ribosomes. Isolated from Streptomyces tenjimariensis ATCC 31603, it exhibits limited antibacterial efficacy against select bacterial strains. Istamycin Y0 is primarily used in microbiological research to study antibiotic resistance mechanisms and the pharmacodynamics of aminoglycosides. -
Bacterial Metabolite
ε-Rhodomycinone is a bacterial metabolite derived from Streptomyces griseoruber that acts as a precursor to Rhodomycin D. This compound plays a critical role in the bioconversion pathway leading to the production of clinically relevant anthracycline antibiotics, including Daunorubicin and Doxorubicin. Its study is significant for understanding antibiotic biosynthesis and developing novel therapeutic agents. -
Bacterial Inhibitor
Negamycin is a bacterial inhibitor that targets protein synthesis by binding to the head domain of the bacterial ribosomal small subunit. This interaction disrupts normal translation, leading to cell death and enhancing the misreading of near-cognate codons. Negamycin is valuable for research applications focused on understanding antibiotic mechanisms and bacterial resistance. -
Anti-Bacterial Agent
Lunatoic acid A functions as an anti-bacterial agent with notable effects against specific bacterial strains. In addition to its antibacterial properties, this compound also exhibits partial anti-mould activity. It is applicable in research focused on microbial inhibition and the development of antimicrobial therapies. -
Anti-Bacterial Agent
γ-Chloronorvaline is an anti-bacterial agent that exhibits resistance against Pseudomonas aeruginosa, Serratia, Klebsiella pneumoniae, and Bacillus subtilis in synthetic media. This compound is particularly useful in research applications focused on combating infections caused by these specific pathogens. Notably, it shows no activity against Escherichia coli, making it a selective agent for targeted bacterial strains. -
Anti-Bacterial Agent
3-epi-Deoxynegamycin is an antibacterial agent that primarily targets Gram-positive bacteria. It exhibits significant antibacterial activity against a wide range of Gram-positive strains, while displaying limited efficacy against Gram-negative bacteria. This compound is valuable for research applications focused on understanding bacterial resistance and developing new therapeutic strategies against bacterial infections. -
Antibacterial Agent
PGE 9262932 is a quinolone antibacterial agent that targets bacterial DNA gyrase and topoisomerase IV, disrupting core processes of bacterial replication. This compound exhibits significant antibacterial activity, making it suitable for research applications focused on infections caused by a variety of bacterial pathogens. It serves as a valuable tool in the study of bacterial resistance mechanisms and the development of novel antimicrobial therapies. -
Bacterial Inhibitor
3-Fluoro-DL-valine is an unnatural amino acid that functions as a bacterial inhibitor by disrupting protein synthesis in targeted bacterial strains. This compound demonstrates significant antibacterial activity, making it a valuable tool in microbiological studies. Additionally, 3-Fluoro-DL-valine can be utilized in peptide synthesis, offering versatile applications for the development of bioactive peptides in biochemical research and drug discovery. Its distinct structural properties position it as a promising candidate for innovative compound research and development. -
Antimicrobial Agent
PD 131628 is an antimicrobial agent and a potent active metabolite of PD 131112. It exhibits two- to four-fold greater activity than Ciprofloxacin, effectively inhibiting all strains of Staphylococcus aureus and Streptococcus pneumoniae. PD 131628 demonstrates strong efficacy against Neisseria spp., Haemophilus influenzae, and Moraxella catarrhalis, with MIC90 values ranging from 0.004 to 0.008 mg/L, making it a valuable tool for antimicrobial research applications. -
Antibacterial Agent
Dapabutan is an antimicrobial agent primarily targeting Gram-positive bacteria. It exhibits potent antibacterial activity, making it suitable for research focused on the development of novel treatments for bacterial infections. Its mechanism of action involves disrupting bacterial cell wall synthesis, thereby inhibiting growth and proliferation. This compound is valuable for studies in microbiology and pharmaceutical development. -
MRSA Antibiotic
MRSA Antibiotic 2 selectively targets methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 2 μg/mL. This compound demonstrates enhanced efficacy against Gram-positive bacteria while exhibiting minimal impact on Gram-negative bacteria and human cells. It is a valuable tool in the study of antibiotic resistance and the development of new therapeutic strategies for treating MRSA infections. -
Anti-Bacterial Agent
Pyloricidin A is an antibiotic that specifically targets Helicobacter pylori, derived from Bacillus sp. HC-70. It exhibits potent anti-H. pylori activity, making it a valuable reagent for studying this pathogen. Pyloricidin A is selective and shows no activity against other bacterial strains or yeast, providing a focused approach for research applications related to H. pylori infections. -
Anti-Bacterial Agent
Dihydrogranaticin is an anti-bacterial agent targeting Bacillus cereus. It exhibits significant antimicrobial activity, making it a valuable tool in the study and development of treatments against bacterial infections. This compound is suitable for research applications focused on antimicrobial resistance and the efficacy of new antibacterial therapies. -
Anti-Bacterial Agent
Coumermycin A2 is an anti-bacterial agent that primarily targets Gram-positive bacteria, displaying weak activity against mycobacterium. This compound has significant applications in research focused on bacterial resistance and the development of novel antibacterial therapies. Its mechanism of action involves inhibition of bacterial growth, providing a valuable tool for studies in microbiology and drug discovery. -
Antibacterial Agent
KY-9 is an antibacterial agent that functions by inhibiting bacterial growth through its targeted mechanism of action. This compound exhibits notable efficacy against a range of Gram-positive and Gram-negative bacteria. As a result, KY-9 serves as a valuable tool in microbiological research and the development of antimicrobial therapies. -
Bacterial
Flambalactone is a degradation product derived from the methanolysis of the antibiotic flambamycin. It targets bacterial systems and exhibits inhibitory activity against various strains of pathogenic bacteria. This compound is useful in research applications focused on understanding antibiotic resistance mechanisms and bacterial cell viability. -
Antibacterial Agent
LB 10517 (sodium) is a cephalosporin antibiotic known for its broad-spectrum antibacterial activity. It effectively targets both Gram-positive and Gram-negative bacteria, including notable pathogens such as Enterobacteriaceae, Pseudomonas aeruginosa, Staphylococcus, and Streptococcus. This compound is valuable for research applications focused on bacterial infections and antibiotic resistance mechanisms. -
Anti-Bacterial Agent
9-Hydroxycrisamicin, an anti-bacterial agent, exhibits weak activity against Gram-positive bacteria with a minimum inhibitory concentration (MIC) ranging from 6.25 to 25 μg/mL. Additionally, 9-Hydroxycrisamicin demonstrates significant growth inhibition in various human tumor cell lines, making it a valuable compound for research in both antibacterial and oncological studies. -
Anti-Bacterial Agent
Kigamicin A is an anti-bacterial agent with demonstrated efficacy against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Its minimum inhibitory concentrations (MICs) range from 0.025 to 0.78 μg/mL, indicating potent antibacterial activity. This compound is valuable in research focused on combating antibiotic-resistant bacterial infections and exploring new therapeutic options. -
Antibacterial Agent
PYO12 is a selective antibacterial compound targeting Gram-positive bacteria. It demonstrates potent activity against S. aureus, B. subtilis, S. pneumoniae, and MRSA, with minimum inhibitory concentrations (MIC) of 1 μg/mL for the first three and 4 μg/mL for MRSA. PYO12 enhances bacterial membrane permeability and upregulates stress-related genes by potentially binding to the C55-PP moiety of lipid II. Its concentration-dependent bactericidal effect, coupled with low toxicity to mammalian cells and lack of hemolytic activity, positions PYO12 as a promising candidate for the development of novel antibiotics focused on bacterial cell wall synthesis. -
Polyketide
Reveromycin C is a polyketide compound originally derived from Streptomyces, exhibiting significant antifungal activity against Candida albicans, with minimum inhibitory concentrations of 2.0 μg/mL at pH 3 and above 500 μg/mL at pH 7.4. It inhibits EGF-induced mitogenic activity in Balb/MK mouse epidermal cells and effectively reverses the morphology of sarcoma-virus-transformed NRK rat kidney cells with an EC50 of 1.58 μg/mL. Additionally, Reveromycin C suppresses the proliferation of KB cells and K562 human chronic myelogenous leukemia cells, both with an IC50 of 2.0 μg/mL, making it a valuable tool for cancer research and antifungal studies. -
Antibacterial Agent
ML370 is an antibacterial agent that functions by inhibiting the activity of the Vibrio cholerae LuxO kinase. This inhibition disrupts bacterial signaling, thereby impeding the growth and virulence of cholera pathogens. ML370 is suitable for research applications focused on infectious diseases, particularly in studies related to cholera and other Vibrio species. -
Anti-Bacterial Agent
Emerimicin III is an anti-bacterial agent primarily targeted against Gram-positive bacteria. This compound exhibits potent inhibitory effects, making it a valuable tool in research focused on bacterial infections and resistance mechanisms. Its unique structure and activity profile facilitate studies into novel therapeutic approaches for combatting Gram-positive pathogens.
