8-Hydroxyquinoline is a lipophilic metal chelator primarily utilized as a fungicide. It demonstrates antimicrobial activity with a minimum inhibitory concentration (MIC) range of 27.56-55.11 μM against clinical isolates of Neisseria gonorrhoeae. The compound is capable of binding copper, facilitating its transport into cells, and has been observed to induce an increase in micronucleated polychromatic erythrocytes, with additional effects on hair depigmentation in murine models. This reagent is valuable for research in metal ion interactions and fungal pathology.
8-Hydroxyquinoline is a lipophilic metal chelator primarily utilized as a fungicide. It demonstrates antimicrobial activity with a minimum inhibitory concentration (MIC) range of 27.56-55.11 μM against clinical isolates of Neisseria gonorrhoeae. The compound is capable of binding copper, facilitating its transport into cells, and has been observed to induce an increase in micronucleated polychromatic erythrocytes, with additional effects on hair depigmentation in murine models. This reagent is valuable for research in metal ion interactions and fungal pathology.
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