Prochlorperazine dimaleate

Catalog No.: A17405
D2R Antagonist
Prochlorperazine dimaleate is an orally active dopamine D2 receptor (D2R) antagonist. It demonstrates notable anti-cancer activity in vitro against a range of cancer cell lines, with IC50 values of 6.4 μM for NOX1, 4.5 μM for NOX2, and 2.3 μM for NOX5. Additionally, prochlorperazine dimaleate exhibits antedesmosidic activity against the dengue virus (DENV). This compound is valuable for research aimed at understanding and treating conditions such as nausea, vomiting, migraine, and schizophrenia.
Grouped product items
Size Price Stock Qty
25mg
$25.00
In stock
50mg
$35.00
In stock
100mg
$50.00
In stock
500mg
$115.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionProchlorperazine dimaleate is an orally active dopamine D2 receptor (D2R) antagonist. It demonstrates notable anti-cancer activity in vitro against a range of cancer cell lines, with IC50 values of 6.4 μM for NOX1, 4.5 μM for NOX2, and 2.3 μM for NOX5. Additionally, prochlorperazine dimaleate exhibits antedesmosidic activity against the dengue virus (DENV). This compound is valuable for research aimed at understanding and treating conditions such as nausea, vomiting, migraine, and schizophrenia.
Product Information
Catalog NumA17405
FormulaC28H32ClN3O8S
Molecular Weight606.09
CAS Number84-02-6
SMILESO=C(O)/C=C\C(O)=O.CN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(Cl)C=C24)CC1.O=C(O)/C=C\C(O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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