Prochlorperazine dimaleate is an orally active dopamine D2 receptor (D2R) antagonist. It demonstrates notable anti-cancer activity in vitro against a range of cancer cell lines, with IC50 values of 6.4 μM for NOX1, 4.5 μM for NOX2, and 2.3 μM for NOX5. Additionally, prochlorperazine dimaleate exhibits antedesmosidic activity against the dengue virus (DENV). This compound is valuable for research aimed at understanding and treating conditions such as nausea, vomiting, migraine, and schizophrenia.
Prochlorperazine dimaleate is an orally active dopamine D2 receptor (D2R) antagonist. It demonstrates notable anti-cancer activity in vitro against a range of cancer cell lines, with IC50 values of 6.4 μM for NOX1, 4.5 μM for NOX2, and 2.3 μM for NOX5. Additionally, prochlorperazine dimaleate exhibits antedesmosidic activity against the dengue virus (DENV). This compound is valuable for research aimed at understanding and treating conditions such as nausea, vomiting, migraine, and schizophrenia.
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