Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Puromycin is an aminoglycoside antibiotic that functions as a protein synthesis inhibitor through its action on bacterial ribosomes. By mimicking aminoacyl-tRNA, puromycin interferes with the elongation step of translation, leading to the premature termination of peptide chains. This compound is widely utilized in molecular biology studies, particularly in selection and maintenance of genetically modified cells, as well as in cancer research to elucidate apoptosis pathways. -
HIV Inhibitor
Oxindole, also known as Indolin-2-one, functions as an HIV inhibitor. This compound is of significant interest in the development of kinase inhibitors, with 2-indolinone derivatives serving as promising lead compounds in various therapeutic applications. Its selective biological activity makes it a valuable reagent for research focused on HIV treatment and other related pathways in viral infections. -
Anti-HSV Agent
Adipic acid (Hexanedioic acid) primarily functions as an anti-HSV agent, exhibiting effective antiviral activity against HSV-1. This compound is characterized by its low toxicity, making it suitable for applications as a food additive and gelling agent. Additionally, adipic acid serves as an important intermediate in the synthesis of lubricants, artificial resins, and plastics, highlighting its versatility in chemical research and industrial applications. -
Bacterial Inhibitor
3,5,4'-Tribromosalicylanilide is a bacterial inhibitor that exhibits potent antituberculosis activity. This compound effectively inhibits the growth of Mycobacterium tuberculosis and Mycobacterium abscessus, demonstrating its potential in combating mycobacterial infections. Additionally, it influences gene expression, suggesting its utility in research focused on antibiotic resistance and microbial gene regulation. -
HIV-1 Inhibitor
Thiamine disulfide is an oxidized dimer of vitamin B1 that serves as a potent inhibitor of HIV-1. Its primary mechanism involves the suppression of HIV-1 transactivator (Tat) activity, which is crucial for viral replication and pathogenesis. This compound is valuable in research applications focused on HIV-1-related studies and the development of antiviral strategies. -
CCR5 Receptor Antagonist
Fuscin is a fungal metabolite that acts as a CCR5 receptor antagonist, exhibiting notable anti-HIV activity. Additionally, it has been identified as an inhibitor of respiration and oxidative phosphorylation, as well as a disruptor of mitochondrial SH-dependent transport-linked functions. This compound serves as a valuable tool in research related to HIV infection and mitochondrial function. -
RXRα Activator
2,4-Di-tert-butylphenol (2,4-DTBP) is a potent RXRα activator and a ligand for human estrogen receptors, exhibiting significant anti-inflammatory and antioxidant properties. This compound has the capacity to induce apoptosis in tumor cells and can activate various RXRα-associated pathways, including LXRα/RXRα and PPARγ/RXRα. Additionally, 2,4-DTBP demonstrates antiviral and antifungal activities while also showing potential to mitigate Aβ-induced neurotoxicity. It serves as a valuable intermediate for synthesizing antioxidants, UV stabilizers, and is utilized in pharmaceutical and fragrance manufacturing. -
Antibacterial Antibiotic
Cephaloridine is a broad-spectrum antibacterial antibiotic that targets bacterial cell wall synthesis. It demonstrates potent activity against a variety of Gram-positive and Gram-negative bacteria. This compound is primarily utilized in research applications focused on understanding antibiotic resistance mechanisms and the pharmacological aspects of cephalosporins. Care should be taken regarding its dose-related nephrotoxicity in experimental settings. -
Antibacterial Agent
Sulfamerazine sodium salt is a sulfonamide antibiotic that targets bacterial dihydropteroate synthase, inhibiting folate synthesis essential for bacterial growth. This compound demonstrates effective antibacterial activity against a range of Gram-positive and Gram-negative pathogens. It is widely utilized in research for studying bacterial infections and the mechanisms of antibiotic resistance. -
Antibacterial Agents and Synergist
Conimine is a steroidal alkaloid with significant antibacterial properties, specifically targeting bacteria such as methicillin-sensitive and methicillin-resistant Staphylococcus aureus. Isolated from the seeds of Holarrhena antidysenteriaca, Conimine not only exhibits intrinsic antibacterial activity but also acts as a potentiator. When used in combination with Penicillin or Vancomycin, Conimine enhances the antibacterial efficacy against both strains of Staphylococcus aureus, making it a valuable reagent for research in antibiotic synergy and resistance studies. -
Antibacterial Agent
Glenthmycin E, an antibacterial agent derived from the Australian sheep pasture bacterium Streptomyces sp. CMB-PB041, exhibits inhibitory activity against a range of bacterial strains while demonstrating no detectable cytotoxicity to eukaryotic cells, including fungal and human carcinoma cells. This compound is pertinent for research focused on bacterial infections and offers potential applications in the development of novel antibacterial therapies. -
Secondary Metabolite
3-Phenylphenol is a secondary metabolite that targets specific gene expression in microbial systems. It has been shown to induce the hbp gene cluster in Pseudomonas sp. strain P1B16, enhancing metabolic pathways of interest. Additionally, 3-Phenylphenol interacts with the Sge1 transcription factor in Fusarium oxysporum f. sp. cubense, disrupting virulence regulation and offering insights into plant pathogen interactions. This compound is valuable for research focused on banana fusarium wilt and other related fungal pathogenic studies. -
Valine-derived Analogue
Isobutyl heptanoate is a valine-derived analogue that exhibits potential biological activity. This compound can be isolated from the volatile metabolites of Aspergillus clavatus NRRL1. Its role in biochemical studies may extend to investigating metabolic pathways and structural biology related to amino acid derivatives. Researchers can utilize isobutyl heptanoate in applications involving metabolic profiling and the exploration of fungal metabolite functionality. -
Drug Isomer
(+)-Mosnodenvir is a drug isomer that acts as an orally active pan-serotype inhibitor of the dengue virus (DENV). It demonstrates potent antiviral activity, with EC50 values ranging from 0.057 to 11 nM across four DENV serotypes. The compound functions by inhibiting the interaction between nonstructural proteins NS3 and NS4B, thereby disrupting viral replication and the synthesis of new viral RNA. (+)-Mosnodenvir has shown significant antiviral efficacy in vitro as well as in animal models, including mice and non-human primates, making it a valuable tool for dengue virus research. -
Bactericide
Poly diallyldimethylammonium chloride is a cationic antimicrobial polymer that acts as a bactericide through its quaternary ammonium side chains. It demonstrates significant microbicidal activity against a range of microorganisms, including bacteria and fungi. This reagent is suited for research applications involving bacterial and fungal infections, such as those caused by E. coli, S. aureus, and C. albicans, making it a valuable tool in the study of antimicrobial resistance and infection control. -
Fungicide
Cyflufenamid is an oxime amide fungicide that targets fungal growth by inhibiting the formation of haustoria, colonies, and spores of Blumeria graminis f. sp. tritici, as well as preventing germ tube elongation in Monilinia fructicola. This compound is valuable for research applications focused on controlling powdery mildew and brown rot, facilitating the study of fungal infection mechanisms and the development of sustainable agricultural practices. -
Antibacterial Agent
Tolyl diiodomethyl sulfone is an organic antibacterial agent that targets bacterial infections. It exhibits significant antibacterial activity without adversely affecting fetal development, as evidenced by studies demonstrating no significant changes in the number of resorbed or dead fetuses, or in the body weight of live fetuses in rat models. This compound is suitable for research applications focusing on the evaluation of antibacterial efficacy and safety profiles in preclinical settings. -
Antibacterial agent
Dimethoxane is an antibacterial agent targeting bacterial growth inhibition. It demonstrates a slow bactericidal effect against a variety of bacterial strains while exhibiting rapid bacteriostatic activity that prevents bacterial replication without causing cell lysis. Additionally, Dimethoxane has been investigated for its role in oncogenesis in animal models. It serves as a low-toxicity preservative in cosmetic applications and effectively controls microbial spoilage in aqueous formulations, emulsions, and suspensions. -
Fungicide
Methfuroxam is a potent fungicide that effectively targets and inhibits key pathogenic fungi, including Colletotrichum salmonicolor, Rhizopus lignosus, and Ganoderma species, which are detrimental to rubber trees and oil palms. Its high level of antifungal activity makes it a valuable tool for research applications aimed at studying plant-pathogen interactions and developing disease management strategies in agriculture. -
Fungicide
Pyrametostrobin is a strobilurin fungicide that targets mitochondrial respiration in fungi. It exhibits broad-spectrum biological activity against various fungal pathogens, including cucumber powdery mildew, blight, rust, and downy mildew. This compound is widely utilized in agricultural research to investigate fungal resistance and the efficacy of fungicides in crop protection. -
Fungicide
Dodemorph is a fungicide that targets ergosterol biosynthesis, disrupting fungal cell membrane integrity. It exhibits effective antifungal activity, making it suitable for studies addressing fungal mildew, particularly in rose cultivation. This reagent can be employed in various research applications focused on plant pathology and disease management in horticultural settings. -
Fungicide
Coumoxystrobin is a methoxyacrylate strobilurin fungicide that targets fungal pathogens. It exhibits potent inhibitory activity against the mycelial growth of Magnaporthe oryzae, enhancing cell membrane permeability and reducing respiration rates. Additionally, Coumoxystrobin demonstrates protective effects in detached barley leaves against Magnaporthe oryzae and impairs ATP activity in Chlorella vulgaris, leading to algal mortality. This reagent is valuable for research on rice blast disease and other related fungal studies. -
Antibacterial Agent
Dipotassium phosphite functions as an antibacterial agent, targeting the development of Phytophthora infestans. This compound effectively reduces the severity of late blight in field-grown tomato plants, leading to improved overall productivity. Dipotassium phosphite is suitable for research focused on late blight management and plant disease resistance. -
Fungicide
4-Dodecyl-2,6-dimethylmorpholine is a morpholine-based fungicide that primarily targets phytopathogenic fungi, including Oomycetes, Ascomycetes, and Basidiomycetes. This compound exhibits antifungal activity and functions as a plant growth regulator, enhancing the efficacy of acylalanine fungicides when used in combination. It is suitable for research applications focused on plant fungal diseases and the mechanisms underlying phytopathogenic fungal infections. -
Fungicide
(E)-Metominostrobin is a strobilurin fungicide that acts by inhibiting mitochondrial respiration in fungal cells. It demonstrates potent activity against a variety of phytopathogenic fungi, making it effective for use in agricultural applications, particularly in strawberry cultivation. This compound aids in protecting crops from fungal diseases, thereby enhancing yield and crop quality. -
Fungicide
Metconazole is a 14α-demethylation inhibitor (DMI) fungicide that targets fungal ergosterol biosynthesis. This compound effectively inhibits mycelial growth and conidial germ tube elongation, demonstrating significant antifungal activity. Additionally, Metconazole has been shown to reduce antioxidant enzyme activities and is particularly effective in decreasing the incidence of Fusarium crown rot in wheat, making it valuable for agricultural research and crop protection studies. -
Phytopathogenic Fungi Inhibitoir
Antifungal agent 157 is a heterocyclic pyridazine compound that targets phytopathogenic fungi. It demonstrates effective inhibitory activity against various fungal strains responsible for plant diseases. This agent is valuable for research focused on controlling fungal infestations in agricultural settings, aiding in the development of strategies for plant disease management. -
Phytopathogenic Fungal Inhibtor
Antifungal agent 156 is a heterocyclic pyridazine compound that acts as a phytopathogenic fungal inhibitor. It exhibits significant antifungal activity, making it suitable for research involving phytopathogenic fungal infections. This reagent can be utilized to explore mechanisms of fungal pathogenesis and to develop new strategies for fungal disease management in agricultural settings. - Propiosyringone is a natural compound resulting from the degradation of Eucalyptus globulus wood by wood-decaying fungi. It serves as a signaling molecule in various biological systems and plays a role in plant-microbe interactions. Research applications include studies on plant immunity, microbial symbiosis, and the effects of fungal metabolites on plant growth and development.
- Bisdionin F is a compound that enhances the antibacterial function of macrophages by inhibiting arginase activity induced by Candida albicans. This action effectively restores nitric oxide production, thereby reinforcing the macrophages' innate immune response. Bisdionin F is relevant for research focused on innate immunity, macrophage activation, and fungal infections.
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Antifungal Inhibitor
Hunnemanine is a protoberberine-type isoquinoline alkaloid that acts as a potent antifungal inhibitor. At a concentration of 1000 ppm, it effectively prevents the spore germination of various phytopathogenic fungi, including Alternaria brassicae, Helminthosporium pennisetti, and Fusarium lini. This compound is valuable for research on the infection mechanisms of phytopathogenic fungi and the development of related control strategies. -
Antibiotic
Kanosamine (3-Amino-3-deoxyglucose) is an antibiotic that targets Saccharomyces cerevisiae and human pathogenic fungi such as Candida albicans. It exhibits antifungal activity by inhibiting cell wall synthesis and blocking the activity of GlcN-6-P synthase, with phosphorylated kanosamine-6-phosphate accumulating in the cytoplasm. This compound is valuable for research applications focused on fungal pathogens and mechanisms of antibiotic action. -
Bacterial Inhibitor
Benzoyleneurea is a bacterial inhibitor that demonstrates significant anti-bacterial activity. This compound serves as a valuable scaffold for the development of novel protein geranylgeranyltransferase-I (PGGTase-I) inhibitors, making it a useful tool in antibiotic research and drug discovery aimed at combating bacterial infections. -
Bacterial Inhibitor
Tenuazonic acid is a mycotoxin belonging to the tetramic acids family, functioning primarily as an inhibitor of bacterial protein biosynthesis by promoting the suppression of new protein release on ribosomes. It exhibits acute toxicity, with oral LD50 values ranging between 81-186 mg/kg in rodents. Tenuazonic acid also acts as a photosystem II inhibitor by preventing electron transport beyond the primary quinone receptor (QA) through its interaction with the D1 protein. Furthermore, this compound has demonstrated antiviral activity against various viruses, including measles and respiratory viruses, and exhibits potential inhibitory effects on skin cancer. -
Antibacterial Agent
Angustifoline, an alkaloid derived from Lupinus angustifolius L., functions as an antibacterial agent. This compound demonstrates significant antimicrobial activity, exhibiting bacteriostatic effects against a range of bacteria, including Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Bacillus thuringiensis. Angustifoline is valuable for research applications focusing on bacterial infections and the development of antibacterial treatments. -
Antibiotic
2-Thiophenecarboxaldehyde is an antibiotic compound that demonstrates significant antibacterial and nematicidal properties. Its biological activity makes it a valuable reagent for research applications focused on antimicrobial mechanisms and nematode pest control. -
Fungal Pigment
Cycloleucomelone is a secondary metabolite functioning as a fungal pigment. It exhibits unique biochemical properties that make it a valuable tool for studies in mycology, particularly in understanding pigment biosynthesis and its role in fungal biology. Research applications include investigating the ecological functions of fungal pigments and their potential interactions with other biological systems. -
Antifungal Agent
(+) -Isocorypalmine is an alkaloid derived from Corydalis cava, functioning primarily as an antifungal agent. This compound exhibits significant antifungal activity, making it a valuable tool for researchers studying fungal infections and potential therapeutic interventions. Its mechanism of action involves disrupting fungal cell integrity, which can be crucial for the development of new antifungal strategies. -
Lanosterol Synthase Inhibitor
Lanopylin A2 is a potent inhibitor of lanosterol synthase (EC 5.4.99.7), demonstrating an IC50 of 18 μM. Its primary mechanism targets the biosynthetic pathway of sterols, making it a valuable tool for studying cholesterol biosynthesis and related metabolic processes. Lanopylin A2 is particularly useful in research involving fungal biochemistry and the development of antifungal therapies. -
HCV Inhibitor
Roseoside is a potent inhibitor targeting the HCV NS5A/B replicase, demonstrating an IC50 of 20 μM. This compound effectively interferes with HCV RNA replication in vitro and exhibits antibacterial properties against both Gram-positive and Gram-negative bacteria, as well as antifungal activity against Candida albicans. Roseoside serves as a valuable research tool for investigating bacterial infections, candidiasis, and Hepatitis A and C virus mechanisms, while demonstrating no cytotoxic effects in human systems. -
Fungicide/Bactericide
Phenazine oxide is a potent fungicide and bactericide, primarily acting on microbial targets to inhibit growth and proliferation. This compound demonstrates significant efficacy in controlling various fungal and bacterial pathogens. It is commonly applied in agricultural research and wood preservation studies, providing a valuable tool for investigating microbial resistance and enhancing plant health. -
Anti-Bacterial Agent
Cephalosporin C is a β-lactam antibiotic primarily effective against Gram-positive and select Gram-negative bacteria. It exhibits stability to penicillinase, thereby enhancing its antimicrobial efficacy. The hydrolysis of Cephalosporin C allows for the production of 7-amino-cephalosporanic acid (7-ACA), a crucial precursor for the synthesis of semi-synthetic cephalosporins. This compound is widely utilized in the development of new antibacterial agents and in the study of antibiotic resistance mechanisms.
