Catalog No.
Product Name
Application
Product Information
Citations
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Anti-Fungal Agent
Saricandin is an antifungal agent that primarily targets glucan synthase, exhibiting an ID50 of 242.0 μg/mL. It demonstrates weak antifungal activity, making it a potential candidate for the study of fungal cell wall synthesis and the development of novel antifungal strategies. Research applications include exploring the role of glucan synthase in fungal biology and assessing the efficacy of compound combinations in antifungal treatments. -
Anti-Fungal Agent
Elizabethin is an antifungal agent that exerts its activity by inhibiting fungal growth. This compound is effective against a variety of fungal pathogens, making it a valuable tool for studying antifungal mechanisms and developing new therapeutic strategies. Its applications extend to research in mycology and infectious disease, providing insights into fungal biology and resistance mechanisms. -
Antimicrobial Agent
Enniatin F functions primarily as an antimicrobial agent with notable insecticidal and antifungal properties. This compound inhibits acyl-CoA, cholesterol acyltransferase (ACAT), making it relevant for research applications focused on lipid metabolism and antimicrobial studies. Its diverse biological activities position it as a valuable tool in understanding mechanisms of action against various microbial and pest challenges. -
Anti-Fungal Agent
Mathemycin B is an anti-fungal agent that exhibits significant inhibitory effects on pathogenic fungi. This compound effectively inhibits the growth of Phytophthora infestans JO8 in vitro, with a minimum inhibitory concentration (MIC) of 7.8 μg/mL. Mathemycin B is useful for research applications focused on fungal pathogenesis and therapeutic development against fungal infections. -
Antibiotic
Antibiotic AB023b is a macrocyclic pentaene antibiotic that targets fungal pathogens. It demonstrates potent antifungal activity against Candida albicans and various plant pathogenic fungi, including Botrytis cinerea, Fusarium moniliforme, and Pythium ultimum. This compound is valuable in research applications focused on understanding antifungal mechanisms and developing new treatments for fungal infections. -
Anti-Fungal Agent
Neoenactin B1 is a potent anti-fungal agent that exhibits significant activity against both yeast-like and filamentous fungal strains. Its biological efficacy makes it a valuable tool for research aimed at understanding fungal pathogenesis and developing therapeutic strategies against fungal infections. Neoenactin B1 is suitable for use in studies exploring drug resistance and the mechanisms of fungal growth inhibition. -
Chitin Deacetylase Inhibitor
CDA-IN-5 is a chitin deacetylase inhibitor with a Ki value of 27.5 μM against PstCDA. This compound exhibits antifungal activity, effectively inhibiting the growth of pathogens such as Rhizoctonia solani, Pyricularia oryzae, and Botrytis cinerea. CDA-IN-5 demonstrates moderate efficacy in controlling rice sheath blight, making it a valuable tool for research in agricultural plant pathology and fungal disease management. -
Inhibitor of Uredospore Germination
Methyl 3,4-dimethoxycinnamate is a potent inhibitor of uredospore germination, targeting fungal spores to impede their growth and development. In addition to its antifungal properties, it also suppresses global DNA methylation in Hep3B cells, making it a valuable reagent for research on epigenetic modifications. This compound is suitable for studies in plant pathology and epigenetics, facilitating further investigation into its biological roles and potential applications. -
Antifungal Agent
Chamaejasmenin D is a potent antifungal agent that targets cellular mitosis. It exhibits significant activity against various fungal pathogens by inhibiting their growth and proliferation. This compound is valuable for research applications focused on antifungal drug development and understanding fungal resistance mechanisms. -
Antibiotic
4-Methoxy-p-toluquinone is a quinone antibiotic that primarily targets bacterial and fungal pathogens. Isolated from fungi such as Coprinus siniilis and Lentinus degener, it exhibits notable antibacterial, mycobacterial, and antifungal activity, although its efficacy is limited against Gram-negative bacteria. Additionally, it may be inactivated in serum, which should be considered in experimental contexts. This compound is valuable for research applications in antibiotic susceptibility and the study of fungal infections. -
Antifungal Antibiotic
Adustin is an antifungal antibiotic that acts as a translation inhibitor. It demonstrates effective inhibition of protein synthesis in a cell-free rabbit reticulocyte lysate system, with an IC50 value of 0.34 μM. This compound is primarily used in research applications focused on investigating fungal infections and the mechanisms of action of antifungal agents. -
Antibiotic
Dechlorogriseofulvin is an antibiotic that targets a range of plant pathogenic fungi. It demonstrates significant inhibitory activity against Botrytis cinerea, Rhizoctonia solani, Pythium ultimum, and Sclerotinia sclerotiorum, with minimum inhibitory concentrations (MIC) of 40.0 µg/ml, 43.9 µg/ml, 81.7 µg/ml, and 28.5 µg/ml, respectively. This compound is valuable for research applications related to plant pathology and fungal resistance studies. -
SDH Inhibitor
SDH-IN-29 is a selective inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 of 0.0709 μM. This compound demonstrates broad-spectrum antifungal activity, with EC50 values of 0.356 μg/mL for Fusarium graminearum, 0.798 μg/mL for Sclerotinia sclerotiorum, and 0.146 μg/mL for Rhizoctonia solani. SDH-IN-29 also shows moderate to significant protective effects against rice blast, wheat scab, and cucumber powdery mildew, making it a valuable tool for agricultural research and fungal disease management. -
Antibiotic
Mollisin is a quinone antibiotic that exhibits potent antifungal activity. It is primarily utilized in research applications focusing on fungal infections and antibiotic resistance mechanisms. This compound can serve as an effective tool for investigating antifungal efficacy and developing new therapeutic strategies against fungal pathogens. -
Antibiotic
Epiderstatin is a glutarimide antibiotic that primarily functions by inhibiting filamentous division induced by epidermal growth factor (EGF) without affecting EGF-receptor kinase activity. Its primary application lies in studying EGF-related cellular processes. While exhibiting only weak antifungal activity, Epiderstatin demonstrates no antibacterial effects, making it less suitable for broader antimicrobial applications. -
Anti-Fungal Agent
Chondramide A is a potent anti-fungal agent that specifically targets various fungal species, including Candida and several yeast types such as Henson yeast and ball-like yeast. It exhibits significant anti-fungal activity but does not affect Gram-positive or Gram-negative bacteria. This compound is valuable for research applications focused on fungal infections and the mechanisms underlying antifungal resistance. -
Antifungal Antibiotic
Phyllosinol is an antifungal antibiotic that targets fungal cell membranes, disrupting their integrity and leading to cell death. This compound exhibits potent antifungal activity against a variety of pathogenic fungi, making it a valuable tool for studying fungal infections. Phyllosinol is utilized in research applications focused on antifungal drug development and mechanisms of antifungal resistance. -
CYP51 Inhibitor
CYP51-IN-32 is a selective inhibitor of CYP51, demonstrating a potent antifungal activity with an IC50 of 0.331 μM against Candida albicans. This compound not only inhibits the growth of Candida albicans by disrupting hyphal formation and biofilm development, but it also releases hydrogen sulfide (H2S), contributing to its antifungal effects. CYP51-IN-32 is suitable for investigating Candida albicans infections and can be formulated into PEG-based nanovesicles for enhanced delivery in research applications. -
Antibacterial/Antifungal Agent
Geninthiocin is a thiopeptide that primarily targets bacterial and fungal pathogens, exhibiting significant antibacterial and antifungal activities. Its mechanism of action includes the inhibition of protein synthesis, making it a valuable tool for studying microbial resistance and potential therapeutic applications. Geninthiocin is used in research to investigate the efficacy of novel antimicrobial agents and to explore the underlying biochemical pathways involved in microbial infections. -
Anti-Fungal Agent
Cladospolide D is an anti-fungal agent derived from the strain of Cladosporium sp. FT-0012. This compound exhibits significant activity against various fungal species, making it a valuable tool in antifungal research. It is primarily utilized in studies aimed at understanding fungal pathogenicity and developing new antifungal therapies. -
Antibiotics
Benanomicin B is an antifungal antibiotic that exhibits notable antibacterial activity against Gram-positive bacteria, specifically Micrococcus luteus and Corynebacterium bovis. This compound serves as a valuable tool in microbiological research, contributing to the study of antibiotic efficacy and resistance mechanisms. Its dual activity against fungal and bacterial pathogens highlights its potential applications in the development of novel antimicrobial therapies. -
Anti-Fungal Agent
Clavamycin C functions as a potent anti-fungal agent, demonstrating strong activity against Candida species. Its antifungal effects can be antagonized by dipeptides or tripeptides, while amino acids do not diminish its efficacy. Notably, Clavamycin C displays no antibacterial activity and does not inhibit β-lactamase enzymes, making it a specific agent for fungal research applications. -
Antibiotic
Serratamolide is a depsipeptide antibiotic with activity against Gram-positive bacteria, mycobacteria, and fungi, although its efficacy may be considered modest. This compound serves as a valuable tool for research into antimicrobial resistance and the mechanisms of action of antibiotic agents. Its diverse biological activities make it suitable for studies focused on developing novel therapeutic strategies against resistant pathogens. -
Anti-Fungal Agent
Cispentacin is an anti-fungal agent that exhibits significant activity against Candida species and other fungi. This compound demonstrates a favorable safety profile, showing no toxicity at doses up to 1 g/kg. It is primarily utilized in research applications focused on the development of treatments for fungal infections. -
Fungal Inhibitor
Prumycin dihydrochloride is an antifungal compound that targets fungal pathogens, specifically demonstrating efficacy against cucumber powdery mildew. This reagent significantly inhibits disease progression while not inducing plant defense gene expression, suggesting its mechanism does not rely on host defensive responses. Additionally, it has shown effectiveness in preventing spore germination of P. fusca, making it valuable for research into fungal pathogenesis and disease management in agriculture. -
Antibiotic
Nystatin A1 is a polyene macrolide antifungal antibiotic derived from Streptomyces noursei. It selectively binds to ergosterol in the fungal cell membrane, resulting in increased membrane permeability and the subsequent leakage of cellular contents. This mechanism effectively inhibits the growth and reproduction of various fungi, making Nystatin A1 an important reagent for antifungal research and studies involving fungal infections. -
Antibiotic
Antibiotic WB is an antibacterial agent with notable antifungal properties, derived from the soil fungus strain 38. This compound exhibits strong inhibitory effects on various pathogenic microorganisms, making it a valuable tool for research in infection control and microbial resistance studies. Its applications extend to evaluating antifungal efficacy and exploring mechanisms of action against resistant strains. -
Antibiotic
Alisamycin is an antibiotic belonging to the manumycin group, primarily targeting Gram-positive bacteria and certain fungi. It exhibits antimicrobial activity and possesses weak antitumor properties, making it useful in various research applications, including studies on bacterial resistance mechanisms and the exploration of its potential therapeutic effects. This compound is valuable for investigations into antibiotic efficacy and the biological pathways underlying its action. -
CYP51 Inhibitor
(Rac)-Ketoconazole is an imidazole antifungal agent that acts as a potent inhibitor of cytochrome P450-dependent 14α-sterol demethylase (CYP51). By disrupting ergosterol synthesis, it induces membrane dysfunction, thereby inhibiting the growth and reproduction of various fungi. This compound is primarily utilized in research relating to fungal infections and the mechanisms of antifungal resistance. -
Antibiotic
Herbarin is a quinone antibiotic that exhibits broad-spectrum antimicrobial activity. It demonstrates effectiveness against Gram-positive and Gram-negative bacteria, as well as the pathogen responsible for Citrus Canker and the fungal pathogen causing potato early blight. Herbarin also shows inhibitory effects on Aspergillus niger and several other fungi, making it a valuable tool for studying bacterial and fungal infections in agricultural and clinical research applications. -
Antifungal Compound
Malvone A is an antifungal compound derived from Malva sylvestris that exhibits significant activity against Verticillium dahliae with an ED50 of 24 µg/mL. This compound serves as a valuable tool for research into the development of anti-infective agents and the study of fungal pathogenesis. Its efficacy against pathogenic fungi makes it a noteworthy candidate for investigations focused on antifungal therapies. -
Fungicide Agent
Tecnazene is a dinitroaromatic fungicide that acts as a plant growth regulator. It effectively inhibits the sprouting of potato tuber buds while demonstrating strong antifungal activity against pathogens responsible for dry rot. Additionally, Tecnazene exhibits acute toxicity in Rattus norvegicus and possesses significant harmful effects on aquatic organisms, including freshwater fish and crustaceans. This compound is primarily utilized in agricultural settings for controlling sprouting and managing dry rot in stored potatoes. -
Antimicrobial Agent
Cyclogregatin is an antimicrobial agent with demonstrated antibacterial and antifungal activity. It effectively inhibits the growth of airy ascites carcinoma with a minimum inhibitory concentration (MIC) of 10 μg/mL. This compound is applicable in research settings focusing on microbial resistance and cancer biology. -
Anti-Fungal Agent
Orchinol is an aromatic derivative with potent antifungal activity. This compound targets fungal cell membrane integrity, disrupting the synthesis of ergosterol and ultimately leading to cell death. Orchinol is utilized in research to explore antifungal mechanisms and develop new therapeutic strategies against fungal infections. -
Antibiotic
Kinamycin B is an antibiotic derived from Streptomyces murayamaensis, primarily targeting fungal pathogens. This compound demonstrates significant antifungal activity, making it a valuable tool for research in microbial resistance and infectious disease studies. Its application extends to exploring the mechanisms of action in antifungal treatments and assessing potential therapeutic developments. -
Antibiotic
Pradimicin Q is an antibiotic that targets bacterial cell membranes. It exhibits cytotoxic effects against human colon HCT-116 cells and murine melanoma B16-F10 cells with IC50 values of 75 μg/mL and 100 μg/mL, respectively. This compound is primarily utilized in research applications focusing on antimicrobial activity and the study of cancer cell response to antibiotic treatment. -
Antibiotic
(E/Z)-Tapinarof (3,5-dihydroxy-4-isopropylstilbene) is a broad-spectrum antibiotic that targets various microbial pathogens. Exhibiting significant antibacterial, antifungal, and anti-nematode activities, (E/Z)-Tapinarof is valuable for research in infectious disease and antibiotic resistance studies. Its diverse biological profile makes it a useful tool for exploring therapeutic strategies against a range of microbial infections. -
Anti-Fungal Agent
Crocacin D is an anti-fungal agent that exhibits significant activity against both yeast and filamentous fungi. This compound demonstrates the ability to inhibit mouse fibroblast cell line L929, indicating its potential cytotoxic effects. Additionally, Crocacin D disrupts the bc1 segment of the electron transport chain in calf heart microsomes, resulting in a redshift of the 569 nm peak in the cytochrome B reduction spectrum, which highlights its role in mitochondrial function studies. -
Antibiotic
Ezomycin A2 is an antifungal antibiotic that targets various phytopathogens. It exhibits significant activity against Sclerotinia sclerotiorum and Botrytis, effectively controlling infections caused by these pathogens, as well as offering protection against candidiasis in crops. Its biological activity makes it a valuable reagent for research applications in plant disease management and crop protection studies. -
Anti-Fungal Agent
Chainin is an anti-fungal agent that exhibits significant activity against yeast and Aspergillus niger. This compound is utilized in research focused on fungal infections and provides valuable insights into the mechanisms of antifungal resistance and therapeutic efficacy. Its effectiveness makes it a critical tool for the study of fungal pathogenesis and potential treatments. -
OSBP Inhibitor
Antifungal agent 107 is an oxysterol-binding protein (OSBP) inhibitor that exhibits antifungal activity. This compound is effective in managing cucumber downy mildew and potato late blight in greenhouse settings, making it a valuable tool for researchers investigating plant pathology and disease control strategies. Its targeted mechanism of action provides a means to explore the role of OSBP in fungal biology. -
Antifungal Agent
Cavipetin C is a diterpene derived from B. cavipes, known for its antifungal properties. This compound effectively inhibits spore formation in Cladosporium cucumericum, making it a valuable tool for studying fungal biology and developing antifungal strategies. Its biological activity supports research in mycology and potential therapeutic applications. -
Antibiotic
Polyoxin G is a nucleoside antifungal antibiotic that primarily targets chitin synthase in fungal cells. It exhibits potent activity against various fungal pathogens, particularly in the management of rice sheath blight. This compound is utilized in agricultural research to develop novel strategies for controlling fungal diseases in crops. -
Macrolide Compound
Dunaimycin A1 is a 24-membered macrolide compound that exhibits immunosuppressive activity. It demonstrates antifungal properties specifically against Aspergillus niger. This compound is valuable for research in the field of autoimmune diseases and can contribute to understanding immune system modulation. -
Antifungal Antibiotic
Pradimicin T1 is an antifungal antibiotic that targets a wide range of filamentous fungi and yeast-like fungi. It exhibits potent antifungal activity, making it a valuable tool in the study of fungal infections and the development of antifungal therapies. Pradimicin T1 is commonly utilized in research applications focusing on fungal biology and mechanisms of resistance. -
Anti-Fungal Agent
Chandrananimycin B acts as an anti-fungal agent with specific activity against Mucor species. In addition, it demonstrates anti-tumor cell effects on various cancer cell lines, including HT29, MFXF 529L, and MCF-7. This compound is valuable for research applications focused on fungal infections and cancer therapeutics. -
Antifungal Agent
NC-1175 hydrochloride is an antifungal agent that targets cell membrane H+-ATPase, disrupting essential ion homeostasis in fungi. This compound demonstrates significant antifungal activity and is employed in research focused on fungal infections and potential therapeutic strategies. Its mechanism may provide insights into treatment options for various fungal diseases. -
Antibacterial Agent
Antibacterial agent 229 is a potent antibacterial compound that targets bacterial membranes and DNA. It exhibits significant antibacterial and antifungal activity by disrupting the integrity of bacterial membranes and intercalating into DNA structures. Furthermore, it inhibits topoisomerase IV with an IC50 value of 10.88 µM, making it a valuable tool for research applications in microbiology and drug development. -
Cer1 Inhibitor
Cs-2d is a selective inhibitor of ceramide synthase 1 (Cer1) with notable potency against C. neoformans. This compound demonstrates significant antifungal activity, effectively inhibiting growth while exhibiting minimal off-target effects on human ceramide synthase 1 (hCerS1). Cs-2d is a valuable tool for research focused on invasive fungal infections, facilitating the study of therapeutic strategies targeting ceramide metabolism. -
Fungal Inhibitor
Griseofulvic acid is a metabolite of the antifungal agent Griseofulvin, acting as a potent fungal inhibitor. It is known to induce protein aggregation and facilitate tubulin polymerization in cell-free assays, making it a valuable tool in the study of fungal biology and cell dynamics. This compound can be utilized in research applications focusing on the mechanisms of antifungal activity and cytoskeletal interactions.
