Catalog No.
Product Name
Application
Product Information
Citations
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Fungal Inhibitor
Kakuol is a naturally derived compound that acts as a fungal inhibitor, targeting fungal cell growth and proliferation. Exhibiting potent antifungal activity, Kakuol is valuable for research applications involving the investigation of fungal infections and the development of antifungal therapies. Its mechanism of action provides insights into novel approaches for combating fungal pathogens. -
SDH Inhibitor
SDH-IN-2 is a potent inhibitor of succinate dehydrogenase (SDH) with an IC50 value of 0.55 μg/mL, demonstrating strong antifungal activity against phytopathogenic fungi, with an average EC50 range of 3.82-9.81 μg/mL. This compound also features an alkyne group, enabling its application in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its dual role as an SDH inhibitor and antifungal agent makes SDH-IN-2 a valuable tool for biochemical research and drug development studies focused on metabolic pathways and fungal diseases. -
Fungal Inhibitor
SCH 51048 is a potent fungal inhibitor that generates active metabolites with demonstrated antifungal properties. Research studies have shown that these metabolites exhibit enhanced activity, making SCH 51048 a valuable compound for investigating antifungal mechanisms and evaluating therapeutic options in fungal infections. This compound serves as a useful tool in the study of fungal biology and the development of new antifungal agents. -
Antifungal Agent
4',7-Dimethoxyisoflavone is a naturally occurring isoflavone derived from the leaves of Albizzia lebbeck, exhibiting significant antifungal properties. This compound has been shown to inhibit the growth of various fungal pathogens, making it a valuable reagent for research in antifungal drug development and related studies. Its potential applications extend to investigations focused on the mechanisms of fungal resistance and the exploration of new therapeutic strategies. -
Analogue of Pyrazine-2-carboxamide
Pyrazine-2-amidoxime is a structural analogue of pyrazine-2-carboxamide, primarily targeting microbial organisms. It exhibits significant antimicrobial activity, effectively killing and inhibiting the growth of Candida albicans, a common fungal pathogen, as well as various Gram-positive bacteria. This compound is valuable for research applications focused on antifungal and antibacterial therapies. -
olysaccharide Copolymer
L-Triguluronic acid is a linear polysaccharide copolymer consisting of three L-guluronic acid units. It serves as a precursor to alginate, a class of unbranched polyanionic polysaccharides that exhibits significant biological activities. This compound is particularly useful in research focused on the development of delivery systems for anti-fungal agents, aiding in the exploration of innovative therapeutic strategies. -
Anti-fungal Agent
Rubropunctamine is an antifungal agent derived from the red Monascus pigment. It demonstrates notable antibacterial activity alongside its efficacy against various yeast and filamentous fungi strains. Additionally, Rubropunctamine has been associated with potential embryotoxic and teratogenic effects, highlighting its relevance in toxicological research and the study of fungal infections. -
Antifungal Agent
ME1111 is an antifungal agent that targets succinate dehydrogenase in Trichophyton species. It exhibits significant efficacy against dermatophytes, making it a valuable tool for the study of fungal infections. Additionally, ME1111 demonstrates excellent penetration into human nails, facilitating research applications focused on onychomycosis and related conditions. -
Fungicide
Fenpropidin is a piperidine-based fungicide that primarily targets a variety of fungal pathogens in cereal crops. It exhibits significant antifungal activity against several human pathogenic yeasts and filamentous fungi, making it valuable in both agricultural and medical research applications. This compound is essential for studying fungal resistance mechanisms and evaluating antifungal efficacy. -
Fungal Inhibitor
Picropodophyllone is an aryltetralin lignan that functions as a fungal inhibitor. This compound exhibits significant antifungal activity, making it a valuable tool for research applications in mycology and the study of fungal pathogenesis. Its isolation from the leaves of Podophyllum hexandrum underlines its natural origin and potential therapeutic implications in combating fungal infections. -
Fungal Inhibitor
L-4-Oxalysine hydrochloride is a naturally occurring compound that acts as a fungal inhibitor. Traditionally isolated from the culture media of Streptomyces roseovirdofuscus, this reagent demonstrates significant antitumor activity. It is utilized in research studies focused on fungal pathogenesis and potential therapeutic applications in oncology. -
Bacteriostat
Sulfometuron-methyl is a potent inhibitor of the enzyme acetolactate synthase (ALS), primarily targeting this pathway to exert its herbicidal effects. In addition to its herbicidal applications, sulfometuron-methyl demonstrates significant antibacterial and antifungal properties, effectively inhibiting the activity of Salmonella typhimurium ALS II and Escherichia coli ALS III. This compound is valuable for research in fields related to microbial resistance and herbicide mechanisms. -
Fungicide Agent
Pyribencarb is a benzylcarbamate-class fungicide that functions primarily as a Qo inhibitor of cytochrome b. It demonstrates strong efficacy against various plant pathogenic fungi, particularly Botrytis cinerea and Sclerotinia sclerotiorum. This compound is valuable for research applications aimed at understanding plant-fungal interactions and developing fungal disease management strategies in agriculture. -
Antifungal Agent
Isorhapontin is an antifungal agent that targets Trichoderma cellobiohydrolase I (CBH I), exhibiting an inhibitory constant (Ki) of 57.2 μM. Additionally, Isorhapontin effectively inhibits the activity of Trichoderma endoglucanase I. This compound is valuable for research into antifungal mechanisms and enzyme activity modulation. -
Antifungal Agent
Stilbamidine dihydrochloride is a diamidine compound that functions as an antifungal agent. It exhibits efficacy against a variety of fungal infections through its inhibitory action on fungal cell growth and replication. This reagent is primarily utilized in research applications aimed at elucidating antifungal mechanisms and developing potential therapeutic strategies against fungal pathogens. -
Antifungal Agent
Macrocarpal I is a phloroglucinol-derived sesquiterpenoid that exhibits potent antifungal activity. It demonstrates significant efficacy against Candida glabrata, with an IC50 value of 0.75 μg/mL. Isolated from the juvenile leaves of Eucalyptus maideni, Macrocarpal I serves as a valuable tool for research on fungal infections and the development of antifungal therapies. -
Fungicide
Diclobutrazol is a systemic fungicide that targets fungal phytopathogens, exhibiting strong activity against rusts and powdery mildews. It is utilized in agricultural research for its effectiveness in controlling a variety of crop diseases, making it an essential tool for studying plant-pathogen interactions and developing disease management strategies in crop production. -
Antibiotic
Bikaverin is a natural antibiotic compound derived from various fungal species, known for its distinctive reddish pigment. This reagent exhibits effective antimicrobial activity, specifically targeting certain protozoa and fungi. It is commonly used in research applications focused on the exploration of microbial resistance and the development of novel antimicrobial therapies. -
Fungal Inhibitor
Exalamide is a potent antifungal agent targeting fungal growth through the inhibition of specific enzymes involved in cellular processes. This compound exhibits significant biological activity against a range of fungal pathogens, making it a valuable tool for research on fungal infections and related diseases. Its application is suited for studies focused on antifungal mechanisms and the development of new therapeutic strategies. -
Antibacterial Agent
Deacylketoconazole is an orally active metabolite of ketoconazole, primarily functioning as an antibacterial agent. This compound demonstrates notable antifungal and antibacterial activities, making it relevant in the study of infectious diseases. Additionally, deacylketoconazole exhibits cytotoxic effects in rat hepatocytes, providing insights into its potential impact on liver function. It serves as a valuable tool in research focused on antimicrobial efficacy and cellular toxicity. -
Monoterpene alcohol
Fenchyl alcohol is a monoterpene alcohol known for its antifungal properties. It effectively inhibits the formation of biofilms and hyphae in Candida albicans, making it valuable for studies on fungal infections. Additionally, Fenchyl alcohol demonstrates a significant inhibitory effect on rumen microbial activity in ruminants such as sheep and deer, aiding research in gastrointestinal microbiology. -
Fungal Inhibitor
2-Butylbenzo[d]isothiazol-3(2H)-one is a fungal inhibitor that displays significant antibacterial and antifungal activity. This compound is utilized in agricultural applications to safeguard crops against pathogenic fungi, making it an essential ingredient in pesticides. Additionally, it is incorporated into coatings to deter mold and algae growth. Its preservative properties also make it valuable in personal care formulations, helping to extend product shelf life. -
Antifungal Agent
Sulbentine is an azole antifungal agent that exhibits both fungistatic and fungicidal activities. It serves as a locally acting antimycotic in vivo, making it valuable for treating a range of fungal infections. Sulbentine is commonly utilized in research applications focused on antifungal mechanisms and drug efficacy studies. -
Fungal Inhibitor
2-Ethylnaphthalene is an alkyl-substituted polyaromatic compound that serves as a fungal inhibitor. It has been shown to negatively correlate with the abundance of Glomus species within arbuscular mycorrhizal fungi communities. This property makes 2-Ethylnaphthalene a valuable reagent for investigating fungal interactions and dynamics in various biological research applications. -
SDHI
Penflufen is a potent succinate dehydrogenase inhibitor (SDHI) that targets the mitochondrial respiratory chain. This compound demonstrates broad-spectrum antifungal activity, effectively combating a variety of fungal diseases such as potato black scurf, wheat sharp eyespot, rice sheath blight, and root rot in peanuts. Penflufen is valuable for research applications in plant pathology and agricultural disease management. -
Antifungal Agent
Antifungal agent 18 is an antifungal agent that acts by disrupting fungal cell wall integrity through targeting the unfolded protein response (UPR), calcineurin, and MAPK pathways. It exhibits broad-spectrum antifungal activity against major human fungal pathogens, demonstrating efficacy in both in vitro and in vivo studies. This compound is suitable for research involving invasive fungal pathogens and cutaneous dermatophytes, providing valuable insight into fungal pathogenesis and potential therapeutic interventions. -
Antifungal Agent
4,6-Dimethoxysalicylaldehyde is an antifungal agent that exhibits significant activity against Candida albicans and moderate activity against Saccharomyces cerevisiae. This compound is utilized in research focusing on antifungal mechanisms and potential therapeutic applications for fungal infections. Its unique structure and activity profile make it a valuable tool for studying the efficacy of antifungal treatments. -
Antiacid/Antiulcer Agent
Magnesium silicate primarily acts as an antacid and antiulcer agent. This compound, comprised of magnesium oxide and silicon dioxide, offers effective relief from gastric discomfort and acidity. Additionally, magnesium silicate serves various research applications, including the development of food additives and the exploration of its piezoelectric properties. Its diverse capabilities also extend to use as a deodorant, decolorizing agent, and antifungal agent in biological systems. -
SARS-CoV-2 Inhibitor
SARS-CoV-2-IN-113 is a sulfonohydrazide derivative designed to inhibit SARS-CoV-2 infection, demonstrating an IC50 of 8.320 μM. This compound exerts significant antiviral activity by blocking viral entry and replication, while also downregulating the expression of key genes and proteins such as Spike, ACE-2, and RdRp. With its high selectivity and low cytotoxicity, SARS-CoV-2-IN-113 serves as a valuable tool for research in the field of SARS-CoV-2 biology and therapeutic development. -
Bacterial Inhibitor
N-Butanoyl-L-homoserine lactone (C4-HSL) is a bacterial inhibitor that functions as a signaling molecule in quorum sensing. This compound demonstrates significant antibacterial activity and effectively disrupts biofilm formation, particularly in Pseudomonas aeruginosa. Research applications include studying bacterial communication and developing strategies to combat antibiotic-resistant infections through targeted inhibition of quorum sensing pathways. -
Bacterial Inhibitor
2-Ethyl-6-methylphenol is an alkylphenol with significant antibacterial properties. This compound has demonstrated efficacy in inhibiting bacterial growth and exhibits potential insecticidal activity, making it a valuable tool in microbiological research and pest control studies. Its role as a bacterial inhibitor can facilitate investigations into microbial resistance and the development of novel antimicrobial agents. -
Antibacterial Agent
4-Chloro-2-methylphenol is an antibacterial agent that effectively inhibits bacterial growth through disruption of cell membrane integrity. Its broad-spectrum antimicrobial activity makes it suitable for use in various pharmaceutical applications, particularly as a preservative and excipient in formulations. This compound is also valuable in research settings focused on studying antibacterial mechanisms and developing new antimicrobial therapies. -
Anti-bacterial Agent
Perillene is a natural compound derived from essential oils, primarily recognized for its antibacterial properties. It exhibits significant antibacterial activity against various pathogens, making it a valuable reagent for research in microbial inhibition and infection prevention. Additionally, perillene has been investigated for its potential antitumor effects, contributing to studies focused on cancer therapeutics and natural product research. -
Antibacterial agent
Gypsogenic acid is a triterpenoid acid with established antibacterial properties, primarily targeting oral bacterial pathogens. It has demonstrated effective minimum inhibitory concentration (MIC) values ranging from 50 to 200 μg/mL against Enterococcus faecalis, Streptococcus salivarius, Streptococcus haematococcus, Streptococcus mutans, and Streptococcus sobrinus. Additionally, Gypsogenic acid has been shown to induce blood cortisone cleavage in isolated mice, with an IC50 of 56.6 μM, making it a promising candidate for further research in antibacterial and trypanoidal applications. -
Antibacterial Agent
Antibacterial agent 265 is a potent antibacterial compound targeting various bacterial strains. It exhibits significant activity against both gram-positive organisms such as Staphylococcus aureus, Micrococcus luteus, and Bacillus subtilis, as well as gram-negative bacteria including Escherichia coli, Pseudomonas aeruginosa, and Flavobacterium devorans. This compound is valuable for research applications related to infection control, antimicrobial resistance, and the development of new antibacterial therapies. -
Bacterial Inhibitor
Upleganan is a polymyxin analogue that functions as a bacterial inhibitor, exhibiting antibiotic activity against multidrug-resistant Gram-negative pathogens. It demonstrates significant efficacy, with minimum inhibitory concentration (MIC) values of 0.125 mg/L against Pseudomonas aeruginosa Pa14 and Acinetobacter baumannii NCTC13301. Upleganan is valuable for research applications focusing on antibiotic resistance and the development of novel antibacterial therapies. -
Bacterial Inhibitor
Gepotidacin (S enantiomer) is a potent bacterial inhibitor that targets bacterial DNA replication and transcription processes. This compound exhibits effective antimicrobial activity against a range of gram-positive and gram-negative bacteria, making it valuable for research in infectious disease models. Its mechanism of action involves inhibition of bacterial topoisomerase, contributing to its bactericidal effects. Gepotidacin (S enantiomer) is primarily applied in studies focused on antibiotic resistance and the development of new therapeutic strategies. -
Antibiotic Adjuvant
PA3552-IN-1 is an antibiotic adjuvant that enhances the efficacy of Polymyxin B against multidrug-resistant Pseudomonas aeruginosa, specifically the DK2 strain. By reducing the expression of the PA3552 gene, PA3552-IN-1 restores bacterial sensitivity, making it a valuable tool for overcoming antimicrobial resistance. This compound is relevant for research applications aimed at developing strategies for treating resistant bacterial infections. -
Metabolite
9-Methylstreptimidone is a microbial metabolite primarily derived from Streptomyces sp. S-885, exhibiting notable antifungal and antiviral properties. It demonstrates activity against various fungal species, including S. sake, S. fragilis, R. rubra, T. rubra, and C. albidus, with minimum inhibitory concentrations (MICs) ranging from 4 to 20 μg/mL. Additionally, 9-Methylstreptimidone has effective antiviral activity against poliovirus, vesicular stomatitis virus (VSV), and Newcastle disease virus (NDV) in vitro (MIC=0.02 μg/mL for all). In vivo studies indicate that this compound enhances survival in mouse models challenged with influenza A2 (H2N2) and C. albicans when administered prior to infection. -
Bacterial Inhibitor
Griselimycin is a cyclic lipopeptide that functions as a bacterial inhibitor by specifically binding to the sliding clamp of bacterial DNA polymerase, while exhibiting no interaction with human proliferating cell nuclear antigen (PCNA). This compound demonstrates potent antibacterial activity against Mycobacterium tuberculosis, including drug-resistant strains, and various Gram-negative bacteria. Griselimycin is useful in research applications focused on bacterial DNA replication and the development of new antibacterial therapeutics. -
Anti-Candida Agent
Antibacterial Agent 27 is a potent anti-Candida agent that targets the growth and proliferation of Candida species. This compound exhibits significant antifungal activity, making it a valuable tool for research in fungal infections and therapeutic development. Its efficacy against a range of Candida strains supports investigations into potential treatments for candidiasis and related diseases. -
Antibacterial Drug
N-(3-Hydroxytetradecanoyl)-DL-homoserine lactone is a member of the N-Acyl homoserine lactone (AHL) family derived from V. alginolyticus strains. This compound demonstrates significant antibacterial activity and plays a crucial role in biofilm formation. Its unique properties make it valuable for studying bacterial communication and quorum sensing mechanisms in various research applications. -
β-lactamase Inhibitor
FPI-1523 is a potent β-lactamase inhibitor targeting CTX-M-15 and OXA-48, exhibiting dissociation constants (Kd) of 4 nM and 34 nM, respectively. Additionally, it inhibits penicillin-binding protein 2 (PBP2) with an IC50 of 3.2 μM. FPI-1523 demonstrates significant antimicrobial activity, making it a valuable reagent for research in antibiotic resistance and bacterial infection studies. -
Beta-lactamase Inhibitor
BLI-489 is a potent beta-lactamase inhibitor that effectively targets class A, class C (AmpC), and class D beta-lactamase producing pathogens. When used in combination with Piperacillin, BLI-489 enhances antimicrobial activity, providing a therapeutic strategy against infections caused by resistant bacteria. This compound is essential for research aimed at understanding and overcoming beta-lactam resistance mechanisms in clinical pathogens. -
Antibacterial Agent
IPrAgCl is an antibacterial agent with demonstrated antiproliferative activity. It exhibits an IC50 of 30 nM against the MCF7 cell line and 35 nM against the KB cancer cell line. Additionally, IPrAgCl induces apoptosis in the HL60 cell line through the translocation of apoptosis-inducing factor from the mitochondria to the nucleus, making it a valuable tool for research in cancer and antibacterial studies. -
Sulfonamide Antibiotic
Sulfadimethoxine-d4 is a deuterium-labeled sulfonamide antibiotic, derived from sulfadimethoxine. This compound exhibits broad-spectrum antimicrobial activity and is utilized in the treatment of various infections, including respiratory, urinary tract, enteric, and soft tissue infections. Sulfadimethoxine-d4 serves as a valuable tool in pharmacokinetic studies and metabolic research involving sulfonamide antibiotics. -
Antibacterial Agent
Macrocarpal A, a potent antibacterial agent derived from the leaves of Eucalyptus macrocarpa, exhibits significant antimicrobial activity. It effectively inhibits the growth of Bacillus subtilis PCI219 with a minimum inhibitory concentration (MIC) of below 0.2 µM, and Staphylococcus aureus FDA209P, with an MIC of 0.4 µM. This compound is valuable for research applications focused on antibacterial efficacy and the development of antimicrobial agents. -
Bacterial Inhibitor
Ganoderol A is a terpenoid derived from Ganoderma lucidum that acts as a bacterial inhibitor. It demonstrates antimicrobial properties and plays a role in inhibiting the cholesterol synthesis pathway. Additionally, Ganoderol A exhibits significant anti-inflammatory effects and provides protection against ultraviolet A (UVA) damage, making it valuable for research in microbial resistance and skin protection strategies. -
Antibacterial Agent
4-Heptyloxyphenol functions as an antibacterial agent, exhibiting significant activity against periodontal pathogens such as Porphyromonas gingivalis, Streptococcus artemidis, and Streptococcus sobrinus, with minimum inhibitory concentrations (MIC) of 0.10, 0.21, and 0.14 mM, respectively. This compound is useful in scientific research focused on oral microbiology and the development of novel antibacterial therapies targeting oral pathogens. -
Antibacterial Agent
Antibacterial Agent 26 is a potent antibacterial compound targeting a wide range of bacterial pathogens. With strong activity against both Gram-positive and Gram-negative bacteria, it is suitable for various research applications including studies on antimicrobial resistance and drug efficacy. This compound is valuable for researchers investigating novel antibacterial strategies and mechanisms of action.
