SARS-CoV-2-IN-113

Catalog No.: A42377
SARS-CoV-2 Inhibitor
SARS-CoV-2-IN-113 is a sulfonohydrazide derivative designed to inhibit SARS-CoV-2 infection, demonstrating an IC50 of 8.320 μM. This compound exerts significant antiviral activity by blocking viral entry and replication, while also downregulating the expression of key genes and proteins such as Spike, ACE-2, and RdRp. With its high selectivity and low cytotoxicity, SARS-CoV-2-IN-113 serves as a valuable tool for research in the field of SARS-CoV-2 biology and therapeutic development.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSARS-CoV-2-IN-113 is a sulfonohydrazide derivative designed to inhibit SARS-CoV-2 infection, demonstrating an IC50 of 8.320 μM. This compound exerts significant antiviral activity by blocking viral entry and replication, while also downregulating the expression of key genes and proteins such as Spike, ACE-2, and RdRp. With its high selectivity and low cytotoxicity, SARS-CoV-2-IN-113 serves as a valuable tool for research in the field of SARS-CoV-2 biology and therapeutic development.
Product Information
Catalog NumA42377
FormulaC14H14N2O5S
Molecular Weight322.34
CAS Number455304-63-9
SMILESCC1=CC=C(C=C1)S(=O)(N/N=C/C2=C(C(O)=C(C=C2)O)O)=O
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