FPI-1523 is a potent β-lactamase inhibitor targeting CTX-M-15 and OXA-48, exhibiting dissociation constants (Kd) of 4 nM and 34 nM, respectively. Additionally, it inhibits penicillin-binding protein 2 (PBP2) with an IC50 of 3.2 μM. FPI-1523 demonstrates significant antimicrobial activity, making it a valuable reagent for research in antibiotic resistance and bacterial infection studies.
FPI-1523 is a potent β-lactamase inhibitor targeting CTX-M-15 and OXA-48, exhibiting dissociation constants (Kd) of 4 nM and 34 nM, respectively. Additionally, it inhibits penicillin-binding protein 2 (PBP2) with an IC50 of 3.2 μM. FPI-1523 demonstrates significant antimicrobial activity, making it a valuable reagent for research in antibiotic resistance and bacterial infection studies.
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