Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
PD117588 is a quinolone antibacterial agent targeting a wide spectrum of bacterial infections. It demonstrates potent activity against both Gram-positive and Gram-negative bacteria, notably showing effectiveness against methicillin-resistant Staphylococcus aureus, coagulase-negative Staphylococci, and Enterococci. Additionally, PD117588 exhibits considerable efficacy against various Gram-negative bacilli, offering a competitive minimum inhibitory concentration compared to other quinolone antibiotics, including imipenem and ceftazidime. This compound is suitable for research applications in antimicrobial resistance and antibiotic development. -
Antibiotic
TANDEM (Des-N-tetramethyltriostin A) is a synthetic antibiotic that primarily inhibits the proliferation of tumor cells. This compound demonstrates significant anticancer activity across various cancer cell lines in vitro, making it a valuable tool for cancer research. TANDEM can be utilized in combination with chemotherapeutic agents to enhance their inhibitory effects. Its mechanism of action involves disruption of cell proliferation and survival pathways, effectively targeting malignant cells during treatment. -
Antibiotic
L-Azatyrosine is an antitumor antibiotic that targets transformed cells by restoring normal phenotypic behavior in those bearing oncogenic Ras genes. Isolated from the bacterium Streptomyces chibaensis, L-Azatyrosine exhibits significant biological activity in cancer research, making it a valuable tool for studying tumor biology and therapeutic interventions. Its unique properties can assist in elucidating the molecular mechanisms underlying oncogenesis and potential treatment strategies. -
Antibiotic
Kapurimycin A3 is an antibiotic with antitumor and antibacterial properties, primarily targeting DNA. Its mechanism involves DNA binding and inducing strand breakage, making it effective in disrupting cellular processes in both bacterial and cancer cells. This compound is isolated from the naturally occurring bacterium Streptomyces, offering a valuable tool for research in cancer therapeutics and antimicrobial studies. -
Antibacterial/Antimalarial
1,2,3,4-Tetrahydronorharman-1-one is a manzamine alkaloid that exhibits antibacterial and antimalarial properties. This compound is derived from an Indonesian sponge and has potential applications in the study of infectious and tropical parasitic diseases. Its unique structural features may offer insights into the development of new therapeutic strategies against challenging pathogens. -
Antitumor Antibiotic
Sarubicin A is an antitumor antibiotic that exhibits potent activity against various Gram-positive and Gram-negative bacteria. Its primary mechanism involves inhibition of bacterial protein synthesis, contributing to its antimicrobial properties. Additionally, Sarubicin A demonstrates significant antitumor activity, making it a valuable reagent for cancer research and the investigation of antibiotic resistance mechanisms. -
Macrocyclic Antibiotic
Soralimixin is a synthetic macrocyclic peptide antibiotic derived from polymyxins, designed for intravenous administration. This compound exhibits potent antibacterial activity against drug-resistant Gram-negative pathogens, making it a valuable tool for studying difficult-to-treat infections. Soralimixin's unique mechanism of action enhances therapeutic options in the fight against antibiotic-resistant bacterial strains, facilitating various research applications in infectious disease. -
β-lactamase Inhibitor
Enmetazobactam iodide is an extended-spectrum β-lactamase inhibitor that targets various β-lactamase enzymes produced by resistant Gram-negative bacteria. This compound effectively enhances the efficacy of β-lactam antibiotics, making it a valuable tool in combating antibiotic resistance. Research applications include studying antibiotic resistance mechanisms and developing novel therapeutic strategies against multidrug-resistant infections. -
Antibacterial Agents
Cefetamet pivoxyl is a cephalosporin antibiotic that targets bacterial cell wall synthesis. It exhibits potent antibacterial activity against a range of enteropathogens, specifically Gram-negative bacteria, with the exception of Pseudomonas aeruginosa, as well as Legionella pneumophila. This compound is primarily utilized in research related to antibacterial efficacy and the development of new antimicrobial therapies. -
Glycopeptide Antibiotic
Balhimycin is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to the D-alanine-D-alanine termini of precursor units. This compound exhibits potent antibacterial activity against strains of staphylococci and various anaerobic bacteria, making it valuable in the study of antibiotic resistance and infection management. Its application extends to research focused on the mechanisms of antibacterial action and the development of novel therapeutic agents. -
Antibacterial Agent
Carumonam is a sulfonated monocyclic β-lactam antibiotic that specifically targets penicillin-binding proteins (PBPs). It demonstrates potent antibacterial activity against Enterobacteriaceae, Pseudomonas aeruginosa, and Haemophilus influenzae, while exhibiting limited to no inhibitory effect on Streptococcus pneumoniae and Staphylococcus aureus. Additionally, Carumonam is resistant to beta-lactamase-mediated hydrolysis, making it a valuable compound for research on antibiotic resistance and infection control studies. -
Antibiotic
Miloxacin is an orally active bacteriostatic agent that primarily targets Gram-negative bacteria. It exhibits antibacterial properties that are comparable to those of Oxolinic acid and Nalidixic acid. Miloxacin is utilized in research applications focusing on the mechanisms of antibiotic action and the development of resistance in bacterial populations. -
Antibiotic/Antitumor Agent
Acetomycin is an antibiotic with potent antitumor activity. It effectively inhibits the growth of CT-8 human colon adenocarcinoma cells with an IC50 of 1.5 μg/mL and L1210 murine leukemia cells with an IC50 of 2.2 μg/mL. This compound can be isolated from the actinomycete WP-2661 and is valuable for research in cancer biology and antibiotic studies. -
Antibiotic
AA-57 is an acidic lipophilic antibiotic derived from the fermentation broth of Actinomycetes strain AA-57, isolated from soil samples in Koriyama City, Fukushima Prefecture, Japan. This compound demonstrates potent antibacterial activity against a diverse range of microorganisms, including Gram-positive, Gram-negative, and acid-fast bacteria. AA-57 is utilized in research focused on antibiotic development and microbial resistance, providing a valuable tool for studying bacterial pathogenesis and therapeutic interventions. -
Antibiotic
OCA 983 is an orally active tetrahydrofuranyl 1β-methylcarbapenem antibiotic that primarily targets bacterial cell wall synthesis. It demonstrates potent inhibitory activity against both class A and class C β-lactamases, making it effective against resistant bacterial strains. This compound possesses a broad antibacterial spectrum and is relevant for research applications involving infectious diseases and antibiotic resistance mechanisms. -
Antitumour Antibiotic
Anthramycin is a potent antitumor antibiotic belonging to the pyrolobenzodiazepine (PBD) family. It exhibits significant cytotoxicity against various cancer cell lines, making it valuable for cancer research. Additionally, Anthramycin has been identified as a strong antagonist of cholecystokinin in the central nervous system of murine models, highlighting its potential in neurobiological studies. This compound is essential for investigations into its mechanisms of action in both cancer therapy and neuropharmacology. -
Antibacterial Agent
Pseudomonic acid C is an antibacterial agent that targets bacterial cell wall synthesis through inhibition of isoleucyl-tRNA synthetase. This compound exhibits potent antibacterial activity against various Gram-positive bacteria, making it a valuable tool for research in microbiology and antibiotic development. Its mechanism offers insights into bacterial resistance and the potential for novel therapeutic strategies. -
Antibiotic
Teicoplanin A2-4 is an antibiotic that targets Gram-positive bacteria, exhibiting potent activity against both aerobic and anaerobic strains. It disrupts cell wall synthesis, leading to bacterial cell lysis. This compound is widely used in research related to bacterial infections and in the study of antibiotic resistance mechanisms. -
Antibiotic
Tetracycline 10-O-ß-D-galactopyranoside is an antibiotic that targets bacterial protein synthesis by inhibiting the 30S ribosomal subunit. This compound exhibits broad-spectrum antimicrobial activity, making it effective against a variety of gram-positive and gram-negative bacteria. It is commonly utilized in molecular biology research for gene expression studies and the development of antibiotic resistance models. -
Antibacterial Agent
Pipemidic acid trihydrate is an antibacterial agent that targets DNA gyrase to exert its effects. This compound demonstrates activity against a range of gram-negative bacteria, including Pseudomonas aeruginosa, as well as certain gram-positive bacteria. It is suitable for research focused on intestinal, urinary, and biliary tract infections, providing a valuable tool for studying bacterial resistance and therapeutic interventions. -
Fluoroquinolone Antibiotic
DC-756 is a fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, crucial enzymes for DNA replication. It exhibits potent antibacterial activity against both Gram-positive and Gram-negative pathogens, demonstrating a 16-fold improvement in minimum inhibitory concentration (MIC) against Ofloxacin-resistant strains compared to Trovafloxacin. Additionally, DC-756 is well-absorbed orally in animal models and exhibits good photostability, making it a valuable reagent for studying bacterial resistance mechanisms and developing novel therapeutic strategies. -
Fluoroquinolone Antibiotic
Tosufloxacin hydrochloride is a fluoroquinolone antibiotic that exhibits broad-spectrum antibacterial activity against both gram-positive and gram-negative bacteria. It functions by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for DNA replication and transcription. This compound is utilized in research applications involving the study of bacterial infections and the development of antibiotic resistance mechanisms. -
Antibiotic
Kazusamycin B is an antibiotic derived from the fermentation broth of Streptomyces sp. No. 81-484. It is known to inhibit cell proliferation and effectively arrests the cell cycle at the G1 phase. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Antibiotic
CB-182804 is a polypeptide antibiotic targeting Gram-negative pathogenic bacteria. It exhibits potent inhibitory activity against a range of pathogens, including Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa, with MIC50 values of 2 μg/mL. This compound is primarily utilized in research focused on refractory infections caused by multidrug-resistant Gram-negative bacteria, providing a valuable tool in the study of antimicrobial resistance and treatment strategies. -
Antibiotic
Zelkovamycin is a cyclic peptide antibiotic that targets bacterial cell growth. It demonstrates potent antimicrobial activity against a range of pathogens, including Xanthomonas oryzae, Pyricularia oryzae, Staphylococcus aureus, and Achromobacter laidlawii, with inhibitory effects observed at concentrations from 0.01 to 300 μg/mL. This compound is valuable for research applications focused on antibiotic resistance and bacterial pathogenesis. -
Antibacterial Agent
Antibacterial Agent 104 is a potent antibacterial compound primarily targeting bacterial pathogens. Demonstrating excellent in vitro antibacterial activity, it also exhibits significant efficacy in vivo against methicillin-resistant Staphylococcus aureus (MRSA). This compound is valuable for research focused on developing treatments for bacterial infections and studying antibiotic resistance mechanisms. -
Bacterial Inhibitor
MT0703 is an aminothiazolyl glycyl cephalosporin that targets bacterial pathogens, exhibiting potent anti-Pseudomonas activity. This compound is studied for its potential in understanding bacterial resistance mechanisms and developing novel therapeutic strategies. Its structure, featuring a 1,5-dihydroxy-4-pyridone-2-carbonyl group, enhances its efficacy against a range of bacterial infections. -
Polyene-Like Antibiotic
Monazomycin is a polyene-like antibiotic produced by the actinobacterium Streptomyces. It exhibits potent antimicrobial activity against a range of pathogenic fungi and can be utilized in research applications focused on antifungal mechanisms. Its unique molecular structure and weight of approximately 1200 Daltons facilitate studies in antibiotic action and resistance. Monazomycin is valuable for elucidating cell membrane interactions and understanding the therapeutic potential of polyene antibiotics. -
Antibiotic
Cefpodoxime sodium is a broad-spectrum antibiotic that targets bacterial cell wall synthesis, effectively inhibiting the growth of both gram-positive and gram-negative bacteria. This compound demonstrates significant antibacterial activity, making it suitable for research applications in conditions such as acute otitis media, sinusitis, and tonsillopharyngitis. Cefpodoxime sodium serves as an important tool in microbiological studies and antibiotic resistance research. -
Antibiotic
Ranbezolid hydrochloride is an oxazolidinone antibiotic that targets the bacterial 50S ribosomal subunit, exhibiting an IC50 of 17 μM against bacterial ribosomes. This compound effectively combats Gram-positive and Gram-negative anaerobes, including strains such as Staphylococcus aureus, Staphylococcus epidermidis, and Bacteroides fragilis. Ranbezolid disrupts cell wall and lipid synthesis, demonstrating rapid bactericidal effects and significant reductions in bacterial load. It is particularly valuable for research involving antibiotics against anaerobic bacterial infections. -
Antibiotic
Cephalochromin is an antibiotic that acts as a specific inhibitor of bacterial fatty acid synthase (FabI). It demonstrates potent inhibitory activity against Staphylococcus aureus and Escherichia coli, with IC50 values of 1.9 µM and 1.8 µM, respectively. Additionally, Cephalochromin is effective against gram-positive methicillin-resistant Staphylococcus aureus (MRSA) and quinolone-resistant S. aureus (QRSA), exhibiting minimum inhibitory concentrations (MIC) in the range of 2-8 µg/mL. This compound is useful in research focused on antibiotic resistance and fatty acid biosynthesis in bacteria. -
Fluoroquinolone Antibiotic
Tosufloxacin tosylate is a fluoroquinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA synthesis. This compound exhibits a broad spectrum of antibacterial activity against both gram-positive and gram-negative microorganisms. It is suitable for research applications involving the study of bacterial infections and the mechanisms of antibiotic resistance. -
Antibiotic
Cefuracetime is a cephalosporin antibiotic that inhibits cell wall synthesis by binding to penicillin-binding proteins. It demonstrates significant antibacterial activity against a range of Gram-positive and Gram-negative pathogens. Cefuracetime is utilized primarily in research applications focused on understanding antibiotic resistance mechanisms and evaluating the efficacy of antibiotic compounds. -
Antibiotic
Josamycin propionate is a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. It exhibits potent antibacterial activity against a range of Gram-positive and some Gram-negative bacteria. This compound is utilized in microbiological studies and clinical research focusing on antibiotic resistance and the efficacy of novel therapeutic agents. -
Antibiotic
TMA-230 is a penem antibiotic with oral bioavailability, primarily targeting bacterial infections. It exhibits potent antibacterial activity, making it valuable for research focused on combating infection. TMA-230 is suitable for studies exploring the mechanisms of antibiotic resistance and the development of new therapeutic strategies against resistant pathogens. -
Antibacterial
GT-1 is a siderophore-linked cephalosporin with notable antibacterial activity. It demonstrates efficacy against clinically significant isolates, including Pseudomonas aeruginosa, Klebsiella oxytoca, Proteus species, Serratia marcescens, and Enterobacter aerogenes. This compound is valuable for research applications focusing on antibiotic resistance and the development of novel antibacterial therapies. -
Antibiotic
Efrotomycin is an orally active antibiotic derived from Streptomyces lactamdurans. It exhibits selective antibacterial activity, although studies indicate it has an insignificant effect on Salmonella typhimurium in terms of quantity, duration, shedding rate, and antimicrobial susceptibility in infected swine. This compound is primarily utilized in research focused on antibiotic efficacy and microbial resistance mechanisms. -
Antibiotic
Kijimicin is a polyether antibiotic that exerts its antibacterial effects by inhibiting protein synthesis in susceptible microorganisms. It is particularly effective against a range of Gram-positive bacteria and some Gram-negative strains, contributing to its utility in antimicrobial research. Kijimicin's ability to combat bacterial infections makes it valuable for studies focused on antibiotic resistance and the development of new therapeutic strategies. -
Antitumor Antibiotic
LL-C 10037α is an antitumor antibiotic derived from the bacterium Streptomyces. This compound has demonstrated significant cytotoxic activity against various cancer cell lines, making it a valuable tool in cancer research. Its unique mechanism of action can assist in exploring therapeutic strategies for tumor treatment and understanding the underlying cellular processes in oncology. -
Antibiotic
Ruboxyl is an anthracycline antibiotic that exhibits significant antitumor activity. It effectively inhibits colorectal cancer liver metastasis by 84% in murine models, suppresses B16 melanoma growth, and enhances survival rates in mice with L1210 and L5178Y leukemia. This compound is useful for exploring mechanisms of tumor biology and developing potential therapeutic strategies for various cancers. -
Antibiotic
Mycinamicin I is a macrolide antibiotic that exerts its antimicrobial activity by inhibiting bacterial protein synthesis. It targets the 50S ribosomal subunit, effectively disrupting the translation process in susceptible bacteria. Mycinamicin I is utilized in research applications focused on antibiotic resistance, bacterial genetics, and the development of novel antimicrobial therapies. -
Antibiotic
Leucomycin A1 is an antibiotic derived from the leucomycin complex produced by Streptomyces kitasatoensis. It exhibits potent antibacterial activity against various Gram-positive bacteria, making it a valuable reagent for microbiological research. Its mechanism of action involves inhibition of protein synthesis, thus providing insights for studies related to antimicrobial resistance and the development of new therapeutic agents. -
Carbapenem Antibiotic
DU-6681 is a carbapenem antibiotic characterized by its broad-spectrum and potent in vitro antibacterial activity against a wide range of gram-positive and gram-negative bacteria. This compound serves as the active parent of DZ-2640 and is valuable for antibacterial research, particularly in studies investigating resistance patterns and efficacy against pathogenic strains. Its robust pharmacological profile makes it an important tool for further exploration in antibiotic development and microbiology. -
Antibiotic
Cefuzonam sodium is a second-generation cephalosporin antibiotic that exhibits antimicrobial activity against Staphylococcus aureus, particularly strains resistant to third-generation cephalosporins. Its primary application includes the prevention of postoperative infections, notably following cesarean deliveries. This compound is valuable in clinical settings for managing bacterial infections where resistance is a concern. -
Antibiotic
Actiphenol is an antibiotic that primarily targets coxsackievirus B3 and influenza A virus, demonstrating IC50 values of 14.37 µg/mL and 34.4 µg/mL, respectively. This compound is an aromatic ketone with weak inhibition activity on eukaryotic translation, sourced from Streptomyces species. Actiphenol serves as a key intermediate in the synthesis of Cycloheximide, making it a valuable reagent in various research applications, including studies on viral infections and translation dynamics. -
Antibiotic
Saccharocarcin B is a macrocyclic lactone antibiotic that primarily targets Gram-positive bacteria, demonstrating significant activity against Micrococcus luteus and Staphylococcus aureus, as well as against the Gram-negative bacterium Chlamydia trachomatis. Its unique structural properties enable it to disrupt essential bacterial processes, making it a valuable reagent for antimicrobial research. Saccharocarcin B is useful in studies focusing on antibiotic resistance and the development of new therapeutic strategies against bacterial infections. -
Antibiotic
6"-Deamino-6"-hydroxyneomycin B is an aminoglycosyl antibiotic targeting bacterial protein synthesis. It exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria, making it a valuable compound for microbiological studies. Additionally, it serves as an important intermediate in the biosynthesis of neomycin, facilitating research into antibiotic production and modification. -
Antibiotic
Kidamycin is a polymyxin antibiotic known for its antimicrobial properties. It exhibits effective antibacterial activity against a range of Gram-negative bacteria, making it valuable in research applications focused on antibiotic resistance and infectious disease. Its unique chemical structure allows for the exploration of mechanisms of action in microbiological studies. -
Antibiotic
Nafcillin sodium is a β-lactam antibiotic effective in inhibiting β-lactamase enzymes. This agent demonstrates significant antibacterial activity against penicillinase-producing staphylococci, making it valuable for studying staphylococcal infections and antibiotic resistance mechanisms in microbial research. Its applications extend to investigating therapeutic options in treating resistant bacterial infections. -
Antibiotic
Ferrocin B is an iron-containing cyclic decapeptide antibiotic that targets Gram-negative bacteria, exhibiting potent antibacterial activity, especially against Pseudomonas aeruginosa. It demonstrates a half effective dose (ED50) of 0.593 mg/kg in a murine infection model against P. aeruginosa. Ferrocin B is an important tool for research in anti-infective therapies and may contribute to the development of novel antimicrobial strategies.
