Catalog No.
Product Name
Application
Product Information
Citations
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Antibiotic
Fluoroquinolonic acid is a bacteriostatic antibiotic that primarily targets bacterial DNA gyrase and topoisomerase IV. This compound demonstrates broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, making it useful in various microbiological studies. Its ability to inhibit bacterial growth positions it as a valuable reagent for research applications in antibiotic resistance and pathogen profiling. -
Lipopeptide Antibiotic
Globomycin is a lipopeptide antibiotic that acts as an irreversible inhibitor of signal peptidase II (LspA). By binding to the peptidase, Globomycin disrupts the processing of prolipoproteins, demonstrating significant antibacterial activity against the mollicute Spiroplasma melliferum with a minimum inhibitory concentration (MIC) of 6.25-12.5 μM. This compound is valuable for research applications focused on bacterial protein processing and antibiotic resistance mechanisms. -
Antibiotic
AMOZ-d5 is a deuterated form of AMOZ, a tissue-bound metabolite of the synthetic nitrofuran antibiotic Furaltadone. This compound exhibits potent antibacterial activity and is primarily utilized in research to study the pharmacokinetics and metabolism of nitrofuran antibiotics. Its stable isotopic labeling allows for detailed analytical investigations in various biological samples. -
Chloramphenicol-Like Antibiotic
Azidamfenicol is a chloramphenicol-like antibiotic that functions by inhibiting ribosomal peptidyltransferase with a Ki value of 22 μM. This broad-spectrum agent exhibits significant antibacterial activity, making it useful in studying bacterial protein synthesis. Additionally, Azidamfenicol serves as a click chemistry reagent due to the presence of an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, DBCO, or BCN groups. This dual functionality allows for versatile applications in chemical biology and bioconjugation strategies. -
Antibiotic
Mellein is an antibiotic derived from the culture fluids of Aspergillus species. This compound exhibits potent antibacterial activity, making it valuable in studying microbial resistance and the mechanisms of action of antibiotics. Its application extends to various fields of microbiological research and drug development, providing insights into potential therapeutic uses. -
Antibiotic
Cefalonium is a first-generation β-lactam cephalosporin antibiotic targeting bacterial cell wall synthesis. It exhibits potent activity against Gram-positive bacteria, particularly staphylococci, making it a valuable tool for studying bovine mastitis. This compound is essential for research applications focused on bacterial infections and antibiotic resistance mechanisms in veterinary medicine. -
Antibiotic
Ulifloxacin is a broad-spectrum quinolone antibiotic that targets bacterial DNA gyrase and topoisomerase IV, inhibiting bacterial DNA replication and transcription. It demonstrates potent antibacterial activity against a variety of Gram-positive and Gram-negative pathogens. Due to its efficacy, Ulifloxacin is utilized in research applications focused on infectious diseases and the development of novel antibacterial therapies. -
HIV-1 Inhibitor
Formycin A is a purine nucleoside antibiotic that acts as a potent inhibitor of human immunodeficiency virus type 1 (HIV-1), exhibiting an EC50 of 10 μM. This compound demonstrates notable antiviral and antitumor activities, making it a valuable tool for research in virology and cancer biology. Its efficacy against HIV-1 makes it a relevant candidate for studies aimed at developing antiviral therapies. -
β-lactam Antibiotic
Azidocillin is a semi-synthetic β-lactam antibiotic that exhibits oral bioavailability and retains its antibacterial activity against various pathogens. Featuring an azide group, Azidocillin serves as both a therapeutic agent and a versatile click chemistry reagent, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition reactions with alkyne-containing compounds. It may also undergo strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN groups. This compound is valuable for investigating osteitis resulting from dental procedures, otitis media, enterococcal septicemia, and other bacterial infections. -
Antibiotic Agent
Metronidazole acetic acid is a metabolite of metronidazole that exhibits mutagenic activity in bacterial systems. As a nitroimidazole antibiotic, it is effective against anaerobic bacteria and protozoa, making it valuable for research in antimicrobial resistance and infectious disease models. Its unique properties allow for exploration of mutagenesis and metabolism in microbial contexts, supporting various biochemical studies. -
Antibiotic
Penicillin G benzathine tetrahydrate is a beta-lactam antibiotic that functions by inhibiting bacterial cell wall synthesis. It possesses potent activity against a wide range of Gram-positive bacteria, making it effective in treating various bacterial infections, including rheumatic fever and syphilis. This compound is commonly utilized in clinical and research settings to study antibiotic resistance and the pharmacokinetics of penicillin derivatives. -
Antibiotic
Aurachin SS is an antibiotic compound derived from the natural product isolated from Streptomyces sp. NA04227. It exhibits significant antibacterial activity, making it a valuable tool for research into microbial resistance and the development of new antimicrobial strategies. This compound is suitable for investigations in microbiology and therapeutic applications targeting bacterial infections. -
Macrolide Antibiotic
Erythromycylamine is a macrolide antibiotic that primarily targets bacterial ribosomes, inhibiting protein synthesis. It exhibits significant antibacterial activity against a range of Gram-positive cocci and Moraxella catarrhalis. This reagent is valuable for research applications focusing on bacterial resistance, antibiotic efficacy studies, and the mechanisms of action of macrolide antibiotics. -
Antibacterial Agent
SABA1 is an antibacterial agent that exhibits significant activity against Pseudomonas aeruginosa and Escherichia coli. With an IC50 of 4.0 µM against E. coli ACC, SABA1 is a valuable tool for researching bacterial infections and antimicrobial resistance in various biological studies. -
Glycopeptide Antibiotic
Chloroorienticin A is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis by targeting the transglycosylation activity in gram-positive bacteria. This compound demonstrates potent antibacterial activity against staphylococci and streptococci, making it a valuable tool for research on antibiotic resistance and bacterial pathogenesis. Its efficacy in inhibiting the growth of these pathogens supports its use in studying the mechanisms of antibiotic action and resistance development in clinical strains. -
Antibiotic
Benapenem is a carbapenem antibiotic that functions by inhibiting bacterial cell wall synthesis through its action on penicillin-binding proteins. This broad-spectrum β-lactam agent is effective against both Gram-positive and Gram-negative bacteria, making it suitable for treating various bacterial infections. Its applications extend to research on antibiotic resistance and the development of novel antimicrobial therapies. -
Antibacterial Agent
Mafenide is a sulfonamide-type antimicrobial agent that primarily targets bacterial nucleotide synthesis. It exhibits potent antibacterial activity against a broad spectrum of pathogens, including both Gram-positive and Gram-negative bacteria, such as Pseudomonas aeruginosa. Mafenide is commonly utilized in research related to wound healing and the treatment of burn injuries, due to its effective antimicrobial properties. -
Glycopeptide Antibiotic
Phleomycin D1 is a glycopeptide antibiotic that targets DNA. It exerts its biological activity by binding to and cleaving DNA, leading to cell death. Additionally, Phleomycin D1 induces cell cycle arrest at the S phase, making it a valuable reagent for research applications in cancer biology and molecular genetics. -
Antibacterial Agent
Gepotidacin mesylate hydrate is an orally active antibiotic that functions as a bacterial type II topoisomerase inhibitor. It interferes with bacterial DNA replication by obstructing topoisomerase enzymes, specifically targeting topoisomerase IV and the B subunit of DNA gyrase. This compound is primarily used in research applications investigating antibacterial mechanisms and the development of novel antimicrobial agents. -
Antibiotic
Actinorhodin is a redox-active microbial secondary metabolite known for its potent antibacterial properties. This blue-pigmented compound functions as a bacteriostatic antibiotic, displaying significant activity against Gram-positive bacteria. Actinorhodin's pH-responsive nature enhances its utility in various research applications, particularly in studies focused on microbial resistance and antibiotic efficacy. -
Cephalosporin Antibiotic
Ceftaroline fosamil (inner) is a cephalosporin antibiotic that acts as an N-phosphono proagent effective against methicillin-resistant Staphylococcus aureus (MRSA). This reagent demonstrates significant antibacterial activity, making it a valuable tool in the study of MRSA infections and antibiotic resistance mechanisms. Its application extends to research aimed at developing new therapeutic strategies for combating resistant bacterial strains. -
Stable Isotope
Rifampicin-d3 is a deuterated derivative of Rifampicin, a potent broad-spectrum antibiotic primarily targeting bacterial infections. It exhibits antimicrobial activity and has been shown to possess anti-influenza virus properties. This stable isotope is valuable for pharmacokinetic studies, mechanism of action investigations, and metabolic research in the field of infectious diseases. -
Antibiotic Agent
Oxytetracycline calcium is a broad-spectrum antibiotic that targets bacterial protein synthesis. It effectively inhibits the binding of aminoacyl-tRNA to the mRNA-ribosomal complex, demonstrating potent activity against both Gram-negative and Gram-positive bacteria. Additionally, Oxytetracycline calcium exhibits antiviral properties, specifically against herpes simplex virus type 1 (HSV-1). This compound is widely utilized in microbiological research and for studying bacterial resistance mechanisms. -
Ephalosporin Antibiotic
Cephapirin is a cephalosporin antibiotic that exhibits broad-spectrum antimicrobial activity by inhibiting bacterial cell wall synthesis. This compound is effective against both Gram-positive and some Gram-negative bacteria, making it valuable in various clinical applications. It is commonly used in research to study antibiotic resistance and evaluate the efficacy of antimicrobial agents. -
Antibiotic
Contezolid acefosamil sodium is an orally active oxazolidinone antibiotic targeting resistant Gram-positive bacteria. It demonstrates significant efficacy in treating complicated skin and soft tissue infections (cSSTI). Notably, this compound exhibits a reduced risk of myelosuppression and minimizes monoamine oxidase inhibition, enhancing its safety profile in clinical applications. -
Antibiotic
Nafcillin is a β-lactam antibiotic that functions as a reversible inhibitor of β-lactamase. It demonstrates potent bactericidal activity against penicillin-resistant strains, particularly Staphylococcus aureus. Nafcillin is commonly utilized in research focused on staphylococcal infections, contributing to the understanding and treatment of resistant bacterial strains. -
Antibiotic
Mycaminosyltylonolide is a potent antibiotic that targets bacterial pathogens. It exhibits significant antibacterial activity by inhibiting luciferase synthesis, disrupting essential bacterial processes. This compound is valuable for research applications focused on antibacterial mechanisms and the development of new therapeutic strategies against resistant bacterial strains. -
Calcium Ionophore Antibiotic, Methanogenic Bacteria Inhibitor
Chlortetracycline is a calcium ionophore antibiotic that primarily targets bacterial protein synthesis by inhibiting the binding of aminoacyl-tRNA to ribosomes. This compound demonstrates potent bactericidal activity and serves as a selective inhibitor of methanogenic bacteria. Chlortetracycline is widely utilized in research applications involving antibiotic resistance studies and metabolic pathway investigations in anaerobic organisms. -
Antibiotic
Carbomycin B is a macrolide antibiotic that primarily targets bacterial ribosomes, inhibiting protein synthesis. Its potent antibacterial activity makes it effective against a variety of Gram-positive bacteria. Carbomycin B is commonly utilized in microbiological research to study antibiotic resistance mechanisms and explore new therapeutic strategies. -
Bacterial Inhibitor
Cefamandole is a semi-synthetic second-generation cephalosporin antibiotic that functions as a bacterial inhibitor by disrupting cell wall synthesis. It exhibits broad-spectrum antimicrobial activity against various Gram-positive cocci and several Gram-negative bacilli, while maintaining resistance to hydrolysis by certain β-lactamases. Although effective in many contexts, it shows limited efficacy against species such as Pseudomonas, Proteus vulgaris, and Providencia stuartii. Cefamandole is primarily excreted in the urine in its active form and is utilized in research applications focused on bacterial infections, although its penetration across the blood-brain barrier is minimal. -
Antifungal Peptide
Pezadeftide is a potent antifungal peptide that targets fungal cells by inducing a rapid mitochondrial response. This mechanism leads to hyperpolarization of the mitochondrial membrane, disrupting cellular function and contributing to antifungal activity. Pezadeftide is valuable for studying antifungal resistance and developing therapeutic strategies against fungal infections. -
Antibacterial Agent
Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent that inhibits dihydropteroate synthase, thereby blocking folic acid synthesis. Its antibacterial properties make it useful in various applications, including blood kinetic studies and research focused on microbial resistance mechanisms. This compound is valuable for scientists investigating the effects of folate metabolism and the therapeutic potential of sulfonamides. -
Antibiotic
Nitrofurantoin sodium is a potent, orally active antibiotic targeting bacterial infections. It exhibits broad-spectrum antibacterial activity, making it particularly effective against urinary tract infections (UTIs), including cystitis and pyelonephritis. This reagent is valuable for research applications focusing on UTI treatment and mechanisms of bacterial resistance. -
Antibiotic
Oleandomycin phosphate is a macrolide antibiotic that exhibits similar structural characteristics to Erythromycin. It functions by inhibiting protein synthesis, specifically by interfering with the translation of activated amino acids into nascent peptide chains at the ribosomal site. This compound demonstrates significant antimicrobial activity, making it useful in various research applications related to bacterial infections and antibiotic resistance studies. -
Antibiotic
4-Epitetracycline hydrochloride is a reversible epimer of Tetracycline, functioning as an antibiotic with notable antibacterial activity. This compound has applications in microbiological research for studying bacterial resistance and the mechanisms of action of tetracycline antibiotics. Its ability to interconvert with Tetracycline in natural settings enhances its relevance in antibiotic studies. -
Antibiotic
Bacitracin A is an antibiotic that targets gram-positive bacteria by inhibiting bacterial cell wall biosynthesis. It forms a complex with long-chain polyisoprenyl pyrophosphates in the presence of metal ions, facilitating the dephosphorylation of the lipid carrier intermediate Css-bactoprenyl pyrophosphate. This mechanism of action underscores its utility in microbiological research and studies involving bacterial infections. -
Trinem Antibiotic
Sanfetrinem is a β-lactamase-stable antibiotic targeting bacterial cell walls. It exhibits broad-spectrum antimicrobial activity against both Gram-positive and Gram-negative bacteria. This compound is valuable in research applications focused on studying bacterial resistance mechanisms and evaluating new antibacterial therapies. -
Bacterial Inhibitor
Cinnamycin is a tetracyclic peptide antibiotic that specifically targets phosphatidylethanolamine (PE). Its primary mechanism involves disrupting bacterial membrane integrity, leading to inhibition of growth in Gram-positive bacteria. Cinnamycin is commonly utilized in microbiological research to study antibiotic resistance and bacterial membrane dynamics. -
Tetracycline Antibiotic
Demecycline, a tetracycline antibiotic, functions by inhibiting bacterial protein synthesis through binding to the 30S ribosomal subunit. It exhibits antibacterial activity against a range of infections, particularly pneumonia and other respiratory tract infections. This compound is widely utilized in research to study antibiotic resistance mechanisms and the pharmacodynamics of tetracycline-class antibiotics. -
Antibiotic
Blasticidin A is a tetraamide acid derivative antibiotic that selectively inhibits aflatoxin production by targeting fungal systems. It demonstrates antimicrobial activity against yeast, making it a valuable tool for studying yeast biology and antifungal mechanisms. Additionally, Blasticidin A is useful in research focused on aflatoxin contamination and the pathogenicity of Aspergillus species. -
Antibiotic
ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. This compound effectively degrades SaFtsZ and inhibits bacterial cell division, demonstrating potent antistaphylococcal activity against S. aureus 8325-4 and MRSA strains, with a minimum inhibitory concentration (MIC) ranging from 0.063 to 256 μg/mL. Additionally, ZG297 has shown efficacy in anti-infectious applications in mouse models, making it a valuable tool for research in antibiotic development. -
Antibiotic
Ormetoprim is an antibiotic that targets bacterial infections in veterinary applications. It is primarily employed in aquaculture and poultry industries to prevent disease transmission in freshwater environments and to enhance growth efficiency in livestock. This compound is essential for maintaining animal health and optimizing production in agricultural settings. -
Antibiotic
Clinafloxacin hydrochloride is a potent fluoroquinolone antibiotic that targets DNA gyrase and topoisomerase IV, effectively inhibiting bacterial DNA replication. It demonstrates broad-spectrum antimicrobial activity against both gram-positive and gram-negative bacteria, as well as anaerobic pathogens in vitro. With IC50 values of 0.92 µg/ml and 1.62 µg/ml against S. aureus, this compound is useful for research applications aimed at understanding antibiotic resistance and developing novel antimicrobial therapies. -
Fluoroquinolone Antibiotic
Grepafloxacin is a fluoroquinolone antibiotic that exhibits potent antibacterial activity against community-acquired respiratory pathogens, particularly Streptococcus pneumoniae. With its high tissue penetration, Grepafloxacin demonstrates an advantageous pharmacodynamic profile, making it valuable for research involving respiratory infections and antibiotic resistance mechanisms. -
Antibacterial Agent
Pisiferic acid is an antibacterial agent that exhibits inhibitory activity against both Gram-negative and Gram-positive bacteria, including Proteus vulgaris, Staphylococcus aureus, and Bacillus subtilis. It serves as a valuable tool for research on bacterial infections, allowing for the exploration of mechanisms of antibacterial resistance and the development of new therapeutic strategies. -
Antibacterial Agent
Dup-721 is an orally active broad-spectrum antibacterial agent that exhibits significant efficacy against a range of both clinically susceptible and resistant bacterial strains, with particular activity against Mycobacterium tuberculosis. This compound is valuable for research applications aimed at understanding bacterial resistance mechanisms and developing novel therapeutic strategies for tuberculosis and other bacterial infections. -
Nucleoside Antibiotic
Psicofuranine is a nucleoside antibiotic that primarily inhibits xanthosine 5'-phosphate aminase and selectively targets GMP synthase. This compound disrupts the growth of parasites, demonstrating dose-dependent inhibitory effects on Plasmodium falciparum. Psicofuranine is a valuable tool for research applications in parasitology and antimicrobial drug development. -
Antibiotic
Cefquinome is a broad-spectrum cephem antibiotic that targets bacterial cell wall synthesis, exhibiting efficacy against a range of Gram-positive and Gram-negative bacteria. Its spectrum of activity includes important pathogens such as Staphylococci, Streptococci, Pseudomonas, and Enterobacteriaceae. Cefquinome is utilized in microbiological research to study antibiotic resistance mechanisms and the effectiveness of therapeutic interventions. -
Carbapenem Antibiotic Combination
Imipenem and cilastatin sodium is a broad-spectrum carbapenem antibiotic combination effective against a wide range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem, the active antibiotic, exhibits rapid bactericidal activity, while cilastatin acts as a renal dehydropeptidase inhibitor, preventing the renal metabolism of imipenem and enhancing its urinary concentration. This combination is commonly utilized in research settings to study antibiotic efficacy and resistance mechanisms. -
Antibiotic
Valnivudine, a nucleoside analogue, exhibits antiviral activity primarily against varicella-zoster virus (VZV). It serves as a proagent to the bicyclic nucleoside analog CF-1743, demonstrating significant efficacy in the treatment of herpes zoster. Following oral administration, Valnivudine is rapidly and extensively converted to CF-1743 in vivo, enhancing its therapeutic potential in clinical applications focused on herpesvirus infections.
