Fig. 1 · Structure
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5-(4-Carboxyphenyl)-10,15,20-triphenylporphyrin
HSV-1/2 Inhibitor
5-(4-Carboxyphenyl)-10,15,20-triphenylporphyrin is a porphyrin compound that targets herpes simplex viruses 1 and 2 (HSV-1/2). It demonstrates potent virucidal activity, achieving inhibition rates of 85% against HSV-1 and 60% against HSV-2, with a maximum noncytotoxic concentration of 5 μg/mL on Vero cells. This compound serves as a valuable tool for studying antiviral mechanisms and can facilitate the synthesis of derivatives with enhanced antiviral efficacy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 95051-10-8 |
| Applications | HSV-1/2 Inhibitor |
| Formula | C45H30N4O2 |
| Molecular Weight | 658.75 |
| SMILES | O=C(C1=CC=C(/C2=C3C=CC(/C(C4=CC=CC=C4)=C5C=C/C(N/5)=C(C6=CC=CC=C6)/C(C=C/7)=NC7=C(C8=CC=CC=C8)/C9=CC=C2N9)=N\3)C=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.