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Publications citing Adooq Products
Sinomenine (Cucoline) Citations (1)
- Zheng Sun,et al. Sinomenine inhibits the growth of melanoma by enhancement of autophagy via PI3K/AKT/mTOR inhibition, Drug Des Devel Ther, 2018, 12: 2413-2421 30122899
Chemical Information
| Catalog Num | A10846 |
|---|---|
| Actions | N/A |
| M. Wt | 329.4 |
| Formula | C19H23NO4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 115-53-7 |
| Synonyms | Cucoline, Kukoline, Coculine, Sabianine A |
| SMILES code | CN1CC[[email protected]@]23CC(=O)C(=C[[email protected]@H]2[[email protected]@H]1CC4=C3C(=C(C=C4)OC)O)OC |
| Chemical Name | No |
Description |
Sinomenine(Cucoline) is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis. | ||||||||||
Targets |
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| Solubility (25°C)* | In vitro | DMSO | 66 mg/mL (200.37 mM) |
|---|---|---|---|
| Water | 66 mg/mL (200.37 mM) | ||
| Ethanol | 8 mg/mL (24.28 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.36 mL | 151.79 mL | 303.58mL |
| 0.5 mM | 6.07 mL | 30.36 mL | 60.72 mL |
| 1 mM | 3.04 mL | 15.18 mL | 30.36 mL |
| 5 mM | 0.61 mL | 3.04 mL | 6.07 mL |
*The above data is based on the productmolecular weight 329.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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