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$0.00 - Zheng Sun, .et al. Sinomenine inhibits the growth of melanoma by enhancement of autophagy via PI3K/AKT/mTOR inhibition, Drug Des Devel Ther, 2018, 12: 2413-2421 PMID: 30122899
Biological Activity
Sinomenine(Cucoline) is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis.
Targets
| In vitro | DMSO | 66 mg/mL (200.37 mM) | |
| Water | 66 mg/mL (200.37 mM) | ||
| Ethanol | 8 mg/mL (24.28 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.36 mL | 151.79 mL | 303.58 mL |
| 0.5 mM | 6.07 mL | 30.36 mL | 60.72 mL |
| 1 mM | 3.04 mL | 15.18 mL | 30.36 mL |
| 5 mM | 0.61 mL | 3.04 mL | 6.07 mL |
*The above data is based on the productmolecular weight 329.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10846 |
|---|---|
| M. Wt | 329.4 |
| Formula | C19H23NO4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 115-53-7 |
| Synonyms | Cucoline, Kukoline, Coculine, Sabianine A |
| SMILES | CN1CC[[email protected]@]23CC(=O)C(=C[[email protected]@H]2[[email protected]@H]1CC4=C3C(=C(C=C4)OC)O)OC |
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