Sinomenine (Cucoline)

Catalog No.: A10846

Sinomenine (Cucoline)

Sinomenine (Cucoline) Chemical Structure

CAS NO. 115-53-7

Sinomenine(Cucoline) is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis.

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200 mg

Regular Price: $60.00

Special Price $48.00

500 mg

Regular Price: $120.00

Special Price $96.00

10mM * 1mL in DMSO

Regular Price: $60.00

Special Price $48.00

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Zheng Sun, .et al. Sinomenine inhibits the growth of melanoma by enhancement of autophagy via PI3K/AKT/mTOR inhibition, Drug Des Devel Ther, 2018, 12: 2413-2421 PMID: 30122899

Biological Activity

Sinomenine(Cucoline) is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis.
Targets
In vitro DMSO 63 mg/mL (191.26 mM)
Water Warmed: 63 mg/mL (191.26 mM)
Ethanol 7 mg/mL (21.25 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.36 mL 151.79 mL 303.58 mL
0.5 mM 6.07 mL 30.36 mL 60.72 mL
1 mM 3.04 mL 15.18 mL 30.36 mL
5 mM 0.61 mL 3.04 mL 6.07 mL

*The above data is based on the productmolecular weight 329.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10846
CAS No. 115-53-7
Formula C19H23NO4
M. Wt 329.4
Purity >98%
Synonyms Cucoline, Kukoline, Coculine, Sabianine A
SMILES CN1CC[[email protected]@]23CC(=O)C(=C[[email protected]@H]2[[email protected]@H]1CC4=C3C(=C(C=C4)OC)O)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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