Sinomenine (Cucoline)

Catalog No.: A10846

Sinomenine (Cucoline)

Sinomenine (Cucoline) Chemical Structure

CAS NO. 115-53-7

Sinomenine(Cucoline) is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis.

Availability: In stock

Package Price Qty
200 mg
$60.00
500 mg
$120.00
10mM * 1mL in DMSO
$60.00
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  • Zheng Sun, .et al. Sinomenine inhibits the growth of melanoma by enhancement of autophagy via PI3K/AKT/mTOR inhibition, Drug Des Devel Ther, 2018, 12: 2413-2421 PMID: 30122899

Biological Activity

Sinomenine(Cucoline) is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis.
Targets
In vitro DMSO 66 mg/mL (200.37 mM)
Water 66 mg/mL (200.37 mM)
Ethanol 8 mg/mL (24.28 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.36 mL 151.79 mL 303.58 mL
0.5 mM 6.07 mL 30.36 mL 60.72 mL
1 mM 3.04 mL 15.18 mL 30.36 mL
5 mM 0.61 mL 3.04 mL 6.07 mL

*The above data is based on the productmolecular weight 329.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10846
M. Wt 329.4
Formula C19H23NO4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 115-53-7
Synonyms Cucoline, Kukoline, Coculine, Sabianine A
SMILES CN1CC[[email protected]@]23CC(=O)C(=C[[email protected]@H]2[[email protected]@H]1CC4=C3C(=C(C=C4)OC)O)OC

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