Streptozotocin (Zanosar)

Name: Streptozotocin (Zanosar)
SKU: A10868
Price: 60 USD
Rating: 5 (10 reviews)

Catalog No.: A10868

O-GlcNAcase inhibitor

Adooq's Streptozotocin (Zanosar) has been cited by 10 publications

Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.

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Grouped product items
Product Name	Price	Stock
Streptozotocin 500mg	$100.00	In stock
Streptozotocin 1g	$170.00	In stock
*Streptozotocin (Zanosar) 10mM 1mL in DMSO**	$60.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

WARNING: Attention California Residents: This product can expose you to chemicals including Streptozotocin (Zanosar) , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's Streptozotocin (Zanosar) has been cited by 10 publications

Zhen Liang, .et al. , Nat Metab, 2023, Jan;5(1):29-40 PMID: 36624157

Alemayehu Toma, .et al. , J Exp Pharmacol, 2022, 14: 309-316 PMID: 36317069

Andressa Braga, .et al. , Braz J Pharm Sci, 2022, 58: e19674

Yuanyuan Du, .et al. , Nat Med, 2022, Feb;28(2):272-282 PMID: 35115708

Karemah A. Alatawi, .et al. , Saudi Journal of Biological Sciences, 2021, 25 June

D.H. Mhya, .et al. , Asian J Exp Biol Sci, 2019, 12 (2): 164-172

Stanley I. R. Okoduwa, .et al. , J Diabetol, 2017, 8(3): 74-85

Stanley I. R. Okoduwa, .et al. , Medicines (Basel), 2017, Dec; 4(4): 73 PMID: 29019956

Stanley I. R. Okoduwa, .et al. , PLoS One, 2017, 12(1): e0170971 PMID: 28129400

Stanley I. R. Okoduwa, .et al. , World J Diabetes, 2016, Dec 15; 7(20): 605-614 PMID: 28031778

Biological Activity

Discription	Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.

Product Information

Catalog Num	A10868
Formula	C8H15N3O7
Molecular Weight	265.2
CAS Number	18883-66-4
SMILES	CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@@H]1O)CO)O)O)N=O
Synonyms	Streptozocin, Zanosar, STZ
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	51 mg/mL (192.29 mM)
	Water	51 mg/mL (192.29 mM)
	Ethanol	Insoluble
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	37.71 mL	188.54 mL	377.07 mL
0.5 mM	7.54 mL	37.71 mL	75.41 mL
1 mM	3.77 mL	18.85 mL	37.71 mL
5 mM	0.75 mL	3.77 mL	7.54 mL

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