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- Stanley I. R. Okoduwa,et al. Validation of the antidiabetic effects of Vernonia amygdalina delile leaf fractions in fortified diet-fed streptozotocin-treated rat model of type-2 diabetes, J Diabetol, 2017, 8(3): 74-85
- Stanley I. R. Okoduwa,et al. Anti-Diabetic Potential of Ocimum gratissimum Leaf Fractions in Fortified Diet-Fed Streptozotocin Treated Rat Model of Type-2 Diabetes, Medicines (Basel), 2017, Dec; 4(4): 73 29019956
- Stanley I. R. Okoduwa,et al. Appropriate Insulin Level in Selecting Fortified Diet-Fed, Streptozotocin-Treated Rat Model of Type 2 Diabetes for Anti-Diabetic Studies, PLoS One, 2017, 12(1): e0170971 28129400
- Stanley I. R. Okoduwa,et al. Evaluation of extraction protocols for anti-diabetic phytochemical substances from medicinal plants, World J Diabetes, 2016, Dec 15; 7(20): 605-614 28031778
|Storage||at -20°C 3 years Powder|
|Synonyms||Streptozocin, Zanosar, STZ|
|SMILES code||CN(C(=O)N[[email protected]@H]1[[email protected]]([[email protected]@H]([[email protected]](O[[email protected]@H]1O)CO)O)O)N=O|
|Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro.|
|Solubility (25°C) *||In vitro||DMSO||53 mg/mL (199.83 mM)|
|Water||53 mg/mL (199.83 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
|In vivo||Saline||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||37.71 mL||188.54 mL||377.07mL|
|0.5 mM||7.54 mL||37.71 mL||75.41 mL|
|1 mM||3.77 mL||18.85 mL||37.71 mL|
|5 mM||0.75 mL||3.77 mL||7.54 mL|
*The above data is based on the productmolecular weight 265.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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