AdipoRon

Catalog No.: A13768

AdipoR1 and AdipoR2 agonist

AdipoRon

AdipoRon Chemical Structure

CAS NO. 924416-43-3

AdipoRon is a novel small-molecule AdipoR agonist; binds to both AdipoR1(Kd= 1.8 uM) and AdipoR2(Kd=3.1 uM). IC50 value: 1.8/3.1 uM(AdipoR1/2, Kd)

Availability: In stock

Package Price Qty
10 mg
$50.00
25 mg
$100.00
50 mg
$160.00
100 mg
$280.00
10mM * 1mL in DMSO
$80.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Uchida T, .et al. The Neuroprotective Effect of the Adiponectin Receptor Agonist AdipoRon on Glutamate-Induced Cell Death in Rat Primary Retinal Ganglion Cells, J Ocul Pharmacol Ther, 2019, Aug 28 PMID: 31460821

Biological Activity

AdipoRon is a novel small-molecule AdipoR agonist; binds to both AdipoR1(Kd= 1.8 uM) and AdipoR2(Kd=3.1 uM). IC50 value: 1.8/3.1 uM(AdipoR1/2, Kd)
Targets
AdipoR1 AdipoR2
1.8 μM(Kd)3.1 μM(Kd)
In vitro DMSO 77 mg/mL (179.69 mM)
Water Insoluble
Ethanol 45 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.34 mL 116.68 mL 233.36 mL
0.5 mM 4.67 mL 23.34 mL 46.67 mL
1 mM 2.33 mL 11.67 mL 23.34 mL
5 mM 0.47 mL 2.33 mL 4.67 mL

*The above data is based on the productmolecular weight 428.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13768
Actions Agonist
CAS No. 924416-43-3
Formula C27H28N2O3
M. Wt 428.52
Solubility DMSO
Purity >98%
SMILES C1CN(CCC1NC(=O)COC2=CC=C(C=C2)C(=O)C3=CC=CC=C3)CC4=CC=CC=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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