CB 300919

Catalog No.: A11359

CB 300919

CB 300919 Chemical Structure

CAS NO. 289715-28-2

CB 300919 is a potential therapy for ovarian cancer. Preclinical data showed that this quinazoline-based compound CB 300919 has a continuous exposure (96 h) growth inhibition IC50 value of 2 nM in human CH1 ovarian tumor xenograft

Availability: In stock

Package Price Qty
5 mg
$240.00
10 mg
$400.00
25 mg
$780.00
50 mg
$1,280.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

CB 300919 is a potential therapy for ovarian cancer. Preclinical data showed that this quinazoline-based compound CB 300919 has a continuous exposure (96 h) growth inhibition IC50 value of 2 nM in human CH1 ovarian tumor xenograft
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.12 mL 85.6 mL 171.2 mL
0.5 mM 3.42 mL 17.12 mL 34.24 mL
1 mM 1.71 mL 8.56 mL 17.12 mL
5 mM 0.34 mL 1.71 mL 3.42 mL

*The above data is based on the productmolecular weight 584.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11359
CAS No. 289715-28-2
Formula C32H34ClN7O2
M. Wt 584.11
Purity >98%
Synonyms CB300919, CB-300919
SMILES CN1CCN(CC1)CC2=NC3=CC(=C(C=C3C(=O)N2C)CN(CC#C)C4=CC=C(C=C4)C(=O)NCC5=CN=CC=C5)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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