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CB 300919 is a potential therapy for ovarian cancer. Preclinical data showed that this quinazoline-based compound CB 300919 has a continuous exposure (96 h) growth inhibition IC50 value of 2 nM in human CH1 ovarian tumor xenograft
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.12 mL | 85.6 mL | 171.2 mL |
| 0.5 mM | 3.42 mL | 17.12 mL | 34.24 mL |
| 1 mM | 1.71 mL | 8.56 mL | 17.12 mL |
| 5 mM | 0.34 mL | 1.71 mL | 3.42 mL |
*The above data is based on the productmolecular weight 584.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11359 |
|---|---|
| CAS No. | 289715-28-2 |
| Formula | C32H34ClN7O2 |
| M. Wt | 584.11 |
| Purity | >98% |
| Synonyms | CB300919, CB-300919 |
| SMILES | CN1CCN(CC1)CC2=NC3=CC(=C(C=C3C(=O)N2C)CN(CC#C)C4=CC=C(C=C4)C(=O)NCC5=CN=CC=C5)Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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