GNF179

Catalog No.: A21042

GNF179

GNF179 Chemical Structure

CAS NO. 1261114-01-5

GNF179 is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.

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5 mg

Regular Price: $378.00

Special Price $302.40

10 mg

Regular Price: $651.00

Special Price $520.80

50 mg

Regular Price: $1,932.00

Special Price $1,545.60

100 mg

Regular Price: $3,864.00

Special Price $3,091.20

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Biological Activity

GNF179 is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.37 mL 116.85 mL 233.7 mL
0.5 mM 4.67 mL 23.37 mL 46.74 mL
1 mM 2.34 mL 11.68 mL 23.37 mL
5 mM 0.47 mL 2.34 mL 4.67 mL

*The above data is based on the productmolecular weight 427.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21042
CAS No. 1261114-01-5
Formula C22H23ClFN5O
M. Wt 427.9
Purity >98%
Synonyms GNF-179, GNF 179
SMILES CC1(C)C2=NC(C3=CC=C(F)C=C3)=C(NC4=CC=C(Cl)C=C4)N2CCN1C(CN)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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