Influenza virus-IN-4 is a potent inhibitor of the influenza virus neuraminidase, exhibiting IC50 values of 3.4 µM, 0.094 µM, 0.79 µM, and 0.077 µM against H5N1, H5N2, H5N6, and H5N8, respectively. This compound demonstrates effective NA-inhibitory activity, contributing to its role in antiviral research. Additionally, Influenza virus-IN-4 exhibits low cytotoxicity, with a CC50 greater than 200 µM, and displays no significant toxicity at doses of 1500 mg/kg in murine models. Its safety profile and efficacy in inhibiting neuraminidase make it a valuable tool for studying influenza virus pathogenesis and developing therapeutic strategies.
Influenza virus-IN-4 is a potent inhibitor of the influenza virus neuraminidase, exhibiting IC50 values of 3.4 µM, 0.094 µM, 0.79 µM, and 0.077 µM against H5N1, H5N2, H5N6, and H5N8, respectively. This compound demonstrates effective NA-inhibitory activity, contributing to its role in antiviral research. Additionally, Influenza virus-IN-4 exhibits low cytotoxicity, with a CC50 greater than 200 µM, and displays no significant toxicity at doses of 1500 mg/kg in murine models. Its safety profile and efficacy in inhibiting neuraminidase make it a valuable tool for studying influenza virus pathogenesis and developing therapeutic strategies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
