Neuraminidase-IN-18 is a potent neuraminidase inhibitor designed to target the neuraminidase enzyme in influenza viruses. It exhibits significant inhibitory activity against H5N1 neuraminidase, with IC50 values of 0.14 μM for the wild-type strain and 0.27 μM for the H5N1-H274Y mutant. This compound effectively inhibits influenza virus replication at the cellular level, making it a valuable tool for research in antiviral drug development and the study of influenza pathogenicity.
Neuraminidase-IN-18 is a potent neuraminidase inhibitor designed to target the neuraminidase enzyme in influenza viruses. It exhibits significant inhibitory activity against H5N1 neuraminidase, with IC50 values of 0.14 μM for the wild-type strain and 0.27 μM for the H5N1-H274Y mutant. This compound effectively inhibits influenza virus replication at the cellular level, making it a valuable tool for research in antiviral drug development and the study of influenza pathogenicity.
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