4-O-Methylepisappanol is a potent neuraminidase inhibitor derived from the heartwood of Caesalpinia sappan. It effectively inhibits neuraminidase activity in various strains of influenza viruses, demonstrating IC50 values of 42.8 µM for A/Chicken/Korea/MS96/96 [H9N2] and 63.2 µM for both A/PR/8/34 [H1N1] and A/Hong Kong/8/68 [H3N2]. This compound is valuable for studying viral pathogenesis and developing antiviral therapies targeting influenza neuraminidase.
4-O-Methylepisappanol is a potent neuraminidase inhibitor derived from the heartwood of Caesalpinia sappan. It effectively inhibits neuraminidase activity in various strains of influenza viruses, demonstrating IC50 values of 42.8 µM for A/Chicken/Korea/MS96/96 [H9N2] and 63.2 µM for both A/PR/8/34 [H1N1] and A/Hong Kong/8/68 [H3N2]. This compound is valuable for studying viral pathogenesis and developing antiviral therapies targeting influenza neuraminidase.
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