Influenza A NP (383-391) (HLA-B27)

Catalog No.: A52141
Immunostimulant
Influenza A NP (383-391) (HLA-B27) is a peptide sequence that functions as an immunostimulant by targeting CD4+ T helper cells. This epitope is known to enhance the activation and proliferation of CD8+ cytotoxic T lymphocytes (CTLs), thereby promoting robust immune responses. It is applicable in research related to breast cancer and other areas of immunotherapy, facilitating the exploration of T cell-mediated responses in cancer models.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionInfluenza A NP (383-391) (HLA-B27) is a peptide sequence that functions as an immunostimulant by targeting CD4+ T helper cells. This epitope is known to enhance the activation and proliferation of CD8+ cytotoxic T lymphocytes (CTLs), thereby promoting robust immune responses. It is applicable in research related to breast cancer and other areas of immunotherapy, facilitating the exploration of T cell-mediated responses in cancer models.
Product Information
Catalog NumA52141
FormulaC117H172N30O30
Molecular Weight2478.80
CAS Number126779-14-4
SequencePhe-Asn-Asn-Phe-Thr-Val-Ser-Phe-Trp-Leu-Arg-Val-Pro-Lys-Val-Ser-Ala-Ser-His-Leu-Glu
Sequence shorteningFNNFTVSFWLRVPKVSASHLE
SMILESC([C@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=CC=C3)N)=O)CC(N)=O)=O)CC(N)=O)=O)=O)[C@@H](C)O)=O)C(C)C)=O)CO)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CN=CN5)C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)CC(C)C)=O)=O)CO)=O)C)=O)CO)=O)[C@H](C)C)=O)CCCCN)=O)CCC4)C(C)C)=O)CCCNC(=N)N)=O)CC(C)C)=O)C=6C=7C(NC6)=CC=CC7
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