Microbiology

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Items 51-100 of 2061

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Catalog No.
Product Name
Application
Product Information
Citations
  1. Neuraminidase inhibitor

    Laninamivir is a neuraminidase inhibitor which is being researched for the treatment and prophylaxis of Influenzavirus A and Influenzavirus B.
  2. ICA

    SK channel inhibitor

    ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC50 of 2.1 ?M.
  3. HCV Polymerase Inhibitor

    Setrobuvir (ANA-598) is a direct-acting antiviral or DAA, is a non-nucleoside inhibitor of the HCV RNA polymerase
  4. alpha-glucosidase I inhibitor

    Celgosivir is an alpha-glucosidase I inhibitor for the potential treatment of HCV infection.
  5. HSV inhibitor

    ASP2151, is a herpes virus helicase-primase inhibitor. ASP2151 had significantly better anti-HSV activity against herpes simplex keratitis than valacyclovir and acyclovir after systemic or topical use.
  6. HIV-1 RT inhibitor

    Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate.
  7. NNRT inhibitor

    Delavirdine is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT).
  8. helicase primase inhibitor

    BAY 57-1293 is a potent helicase primase inhibitor. BAY 57-1293 inhibits replication of herpes simplex virus (HSV) type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the viral primase-helicase complex.
  9. Transcriptase inhibitor

    Abacavir sulfate is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS.
  10. HIV integrase inhibitor

    MK-2048 is a second generation integrase inhibitor, intended to be used against HIV infection.
  11. HIV Entry Inhibitor

    BMS-806, also known as BMS-378806 , is a type of medicine called an entry inhibitor. Entry inhibitors work by blocking HIV from entering human cells. BMS-378806 (BMS-806) is a small molecule that blocks the binding of host-cell CD4 with viral gp120 protein and therefore inhibits the first steps of HIV-1 infection.
  12. Polymerase inhibitor

    Balapiravir (R1626, RG1626) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479).
  13. NNRT inhibitor

    Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
  14. HSV DNA replication inhibitor

    Fiacitabine is a selective inhibitior of DNA replication of herpes simplex virus(HSV) with IC50 values of 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively.
  15. HIV-1 integrase inhibitor

    HIV-1 integrase inhibitor is uesful for anti-HIV.
  16. HIV-1 integrase inhibitor

    HIV-1 integrase inhibitor 2, in the treatment of human immunodeficiency virus (HIV) infection.
  17. NS3 protease inhibitor

    Narlaprevir is a potent, selective, orally bioavailable NS3 protease inhibitor(Ki=6 nM; EC90=40 nM)
  18. HIV-1 inhibitor

    NBD-557 is a potentially HIV-1 inhibitor.
  19. HCV Polymerase Inhibitor

    HCV-796 is a selectively inhibitor of hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase.
  20. influenza virus neuraminidase inhibitor

    Oseltamivir acid (GS 4071), the active metabolite of Oseltamivir phosphate, is an orally bioavailable, potent and selective inhibitor of influenza virus neuraminidase (IC50=2 nM) with activity against both influenza A and B viruses.
  21. HCV RNA polymerase inhibitor

    PSI-6206 is the deaminated derivative of PSI-6130, which is a potent inhibitor of hepatitis C virus (HCV) replication in the subgenomic HCV reolicon system.
  22. influenza virus neuraminidase (NA) inhibitor

    Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes.
  23. HCV NS5B polymerase inhibitor

    Mericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication.
  24. HCV replication inhibitor

    R-1479 is a specific inhibitor of HCV replication in the HCV subgenomic replicon system (IC50=1.28 μM).
  25. NNRT inhibitor

    Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
  26. PC-PLC inhibitor

    SPK-601 (LMV-601) is an inhibitor of the phosphatidylcholine-specific phospholipase C (PC-PLC). SPK-601 also can be used as an antimicrobial agent.
  27. HIV Protease Inhibitor

    Saquinavir mesylate is an HIV Protease Inhibitor used in antiretroviral therapy.
  28. HCV NS3/4A protease inhibitor

    Simeprevir is a potent inhibitor of HCV NS3/4A protease (Ki = 0.36 nM) and viral replication (replicon EC50 = 7.8 nM).
  29. NS5B polymerase inhibitor

    Tegobuvir (GS-9190 is a non-nucleoside NS5B polymerase inhibitor.
  30. RSV fusion inhibitor

    TMC353121 is a potent RSV fusion inhibitor in vitro, Antiviral agents and a novel candidate for RSV disease treatment.
  31. HCV NS3/4A protease inhibitor

    Vaniprevir is a non-covalent competitive inhibitor of the hepatitis C virus (HCV) NS3/4A protease.
  32. HIV protease inhibitor

    Darunavir Ethanolate (Prezista) is an HIV protease inhibitor.
  33. NNRT inhibitor

    MIV-150 is a nonnucleoside reverse transcriptase (NNRT) inhibitor, blocking HIV-1 and HIV-2 infections, with an EC50<1 nM against HIV-1/HIV-2MN.
  34. HCV NS3/4A protease inhibitor

    Voxilaprevir (GS-9857) is a fluorinated macrocyclic hepatitis C virus (HCV) nonstructural protein (NS) 3/4A protease inhibitor with potent in vitro antiviral activity against genotypes 1-6 HCV and broad coverage of NS3/4A protease polymorphisms. GS-9857 improves coverage against commonly encountered NS3 resistance-associated variants (RAVs).
  35. bacterial receptor QseC inhibitor

    LED209 is a potent small molecule inhibitor of bacterial receptor QseC, is a potent prodrug that is highly selective for QseC.
  36. HCV NS5B polymerase inhibitor

    Deleobuvir (BI207127) was a non-nucleoside hepatitis C virus NS5B polymerase inhibitor for the treatment of hepatitis C

  37. CCR5 entry inhibitor

    Aplaviroc is a CCR5 entry inhibitor developed for the treatment of HIV infection.
  38. HCV NS3 inhibitor

    GS-9451 is a potent macrocyclic HCV NS3 PI that achieved a median maximal change in HCV RNA of 3.6 log10 IU/mL (range, -4.7 log10 to -3.1 log10 IU/mL) following 3-day monotherapy in treatment-nave patients with HCV genotype 1 infection during phase I.
  39. HIV protease inhibitor

    PNU-103017 is an HIV protease inhibitor.
  40. CCR2/CCR5 inhibitor

    Cenicriviroc is an experimental drug candidate for the treatment of HIV infection.Cenicriviroc is an inhibitor of CCR2 and CCR5 receptors, allowing it to function as an entry inhibitor which prevents the virus from entering into a human cell.
  41. Influenza virus inhibitor

    JNJ4796 is an oral active fusion inhibitor of influenza virus, neutralizing influenza A group 1 viruses by inhibiting hemagglutinin (HA)-mediated fusion.
  42. HCV NS3/4a inhibitor

    MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants.
  43. beta-lactamase inhibitor

    Durlobactam, also known as ETX2514, is a beta-lactamase inhibitor drug candidate.
  44. nucleotide analog HCV inhibitor

    PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977). Sofosbuvir (PSI-7977) is a selective and highly active nucleotide analog inhibitor of HCV.
  45. HCV NS5A inhibitor

    MK 8742, also known as Elbasvir, is a HCV NS5A inhibitor, which is an all-oral, interferon-free regimen for the treatment of HCV infection.
  46. HIV Integrase Inhibitor

    GSK1265744 (GSK744) is a potential inhibitor of HIV integrase with IC50 value of 3 nM
  47. HCV NS3/4A protease inhibitor

    GS-9451, a novel hepatitis C virus (HCV) nonstructural 3/4a (NS3/4a) protease inhibitor, is highly active in patients infected with HCV genotype 1 (GT 1).
  48. HCV Protease Inhibitor

    Faldaprevir is a hepatitis C virus protease inhibitor.
  49. HIV-1 attachment inhibitor

    BMS-626529 is a potent HIV-1 attachment inhibitor. BMS-663068 is also the phosphonooxymethyl prodrug of BMS-626529 that targets HIV-1 gp120 and prevents its binding to CD4(+) T cells.
  50. 1,3-beta-D-glucan synthesis inhibitor

    Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis.

Items 51-100 of 2061

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