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Biological Activity
Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes.
| In vitro | DMSO | 0.18 mg/mL (0.47 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.15 mL | 130.74 mL | 261.47 mL |
| 0.5 mM | 5.23 mL | 26.15 mL | 52.29 mL |
| 1 mM | 2.61 mL | 13.07 mL | 26.15 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.23 mL |
*The above data is based on the productmolecular weight 382.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11531 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1041434-82-5 |
| Formula | C15H34N4O7 |
| M. Wt | 382.45 |
| Purity | >98% |
| Synonyms | RWJ 270201 trihydrate, RWJ270201, RWJ-270201; BCX 1812 trihydrate, BCX1812, BCX-1812 |
| SMILES | O[[email protected]]1[[email protected]]([[email protected]](C(CC)CC)NC(C)=O)([H])[[email protected]](NC(N)=N)C[[email protected]@H]1C(O)=O.[H]O.[H]O.[H]O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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